Analysis notes
- Updated 4/23 with new weights, only included Stage 2
results, and harmonized y-axis
- Reference timepoint is fixed at 158 days for Stage 1, and 124 days
for Stage 2, which is the minimum timepoint for the latest COVID-19
endpoint across both vaccine and placebo arms.
- Adjusted for standardized_risk_score.
- Showing estimates with pointwise confidence intervals. Both raw
results and results assuming monotonicity are shown. For the VE scaled
graphs, only included graphs assuming monotonicity.
- CIs for risk in graphs are bounded between 0 and 1. CIs for VE in
graphs are bounded above by 1.
Stage 2
IgG Spike Index
Vaccine
Unscaled (not monotone)

| 3.32 |
2100 |
0.00522 |
0.00105 |
3.17e-03 |
0.00727 |
| 3.42 |
2650 |
0.00594 |
0.00134 |
3.32e-03 |
0.00855 |
| 3.52 |
3340 |
0.00594 |
0.00134 |
3.32e-03 |
0.00855 |
| 3.62 |
4200 |
0.00594 |
0.00134 |
3.32e-03 |
0.00855 |
| 3.72 |
5290 |
0.00599 |
0.00136 |
3.33e-03 |
0.00865 |
| 3.82 |
6660 |
0.00599 |
0.00136 |
3.33e-03 |
0.00866 |
| 3.92 |
8380 |
0.00600 |
0.00136 |
3.33e-03 |
0.00866 |
| 4.02 |
10500 |
0.00606 |
0.00139 |
3.34e-03 |
0.00878 |
| 4.12 |
13300 |
0.00606 |
0.00139 |
3.34e-03 |
0.00878 |
| 4.22 |
16700 |
0.00609 |
0.00138 |
3.39e-03 |
0.00880 |
| 4.32 |
21000 |
0.00609 |
0.00138 |
3.39e-03 |
0.00880 |
| 4.42 |
26500 |
0.00609 |
0.00138 |
3.39e-03 |
0.00879 |
| 4.52 |
33400 |
0.00619 |
0.00139 |
3.46e-03 |
0.00892 |
| 4.62 |
42000 |
0.00631 |
0.00143 |
3.51e-03 |
0.00911 |
| 4.72 |
52900 |
0.00633 |
0.00143 |
3.53e-03 |
0.00913 |
| 4.82 |
66600 |
0.00634 |
0.00144 |
3.53e-03 |
0.00916 |
| 4.92 |
83800 |
0.00679 |
0.00155 |
3.74e-03 |
0.00983 |
| 5.02 |
105000 |
0.00657 |
0.00153 |
3.57e-03 |
0.00957 |
| 5.12 |
133000 |
0.00669 |
0.00160 |
3.56e-03 |
0.00983 |
| 5.22 |
167000 |
0.00724 |
0.00180 |
3.72e-03 |
0.01080 |
| 5.32 |
210000 |
0.00641 |
0.00186 |
2.77e-03 |
0.01000 |
| 5.42 |
265000 |
0.00567 |
0.00193 |
1.89e-03 |
0.00946 |
| 5.52 |
334000 |
0.00588 |
0.00206 |
1.85e-03 |
0.00991 |
| 5.62 |
420000 |
0.00294 |
0.00145 |
9.26e-05 |
0.00578 |
| 5.72 |
529000 |
0.00243 |
0.00157 |
-6.56e-04 |
0.00551 |
Unscaled (monotone)

| 3.32 |
2100 |
0.0000 |
0.00619 |
0.00105 |
4.14e-03 |
0.00824 |
| 3.42 |
2650 |
0.0117 |
0.00619 |
0.00134 |
3.57e-03 |
0.00881 |
| 3.52 |
3340 |
0.0117 |
0.00619 |
0.00134 |
3.57e-03 |
0.00881 |
| 3.62 |
4200 |
0.0117 |
0.00619 |
0.00134 |
3.57e-03 |
0.00881 |
| 3.72 |
5290 |
0.0175 |
0.00619 |
0.00136 |
3.53e-03 |
0.00885 |
| 3.82 |
6660 |
0.0180 |
0.00619 |
0.00136 |
3.52e-03 |
0.00885 |
| 3.92 |
8380 |
0.0186 |
0.00619 |
0.00136 |
3.52e-03 |
0.00885 |
| 4.02 |
10500 |
0.0244 |
0.00619 |
0.00139 |
3.47e-03 |
0.00891 |
| 4.12 |
13300 |
0.0244 |
0.00619 |
0.00139 |
3.47e-03 |
0.00891 |
| 4.22 |
16700 |
0.0371 |
0.00619 |
0.00138 |
3.48e-03 |
0.00889 |
| 4.32 |
21000 |
0.0371 |
0.00619 |
0.00138 |
3.48e-03 |
0.00889 |
| 4.42 |
26500 |
0.0377 |
0.00619 |
0.00138 |
3.49e-03 |
0.00889 |
| 4.52 |
33400 |
0.0542 |
0.00619 |
0.00139 |
3.46e-03 |
0.00892 |
| 4.62 |
42000 |
0.0738 |
0.00619 |
0.00143 |
3.39e-03 |
0.00898 |
| 4.72 |
52900 |
0.0802 |
0.00619 |
0.00143 |
3.38e-03 |
0.00899 |
| 4.82 |
66600 |
0.0818 |
0.00619 |
0.00144 |
3.37e-03 |
0.00900 |
| 4.92 |
83800 |
0.1550 |
0.00619 |
0.00155 |
3.14e-03 |
0.00923 |
| 5.02 |
105000 |
0.1700 |
0.00619 |
0.00153 |
3.19e-03 |
0.00919 |
| 5.12 |
133000 |
0.2090 |
0.00619 |
0.00160 |
3.05e-03 |
0.00933 |
| 5.22 |
167000 |
0.2660 |
0.00619 |
0.00180 |
2.67e-03 |
0.00971 |
| 5.32 |
210000 |
0.3650 |
0.00619 |
0.00186 |
2.55e-03 |
0.00983 |
| 5.42 |
265000 |
0.4840 |
0.00577 |
0.00193 |
1.99e-03 |
0.00955 |
| 5.52 |
334000 |
0.6300 |
0.00577 |
0.00206 |
1.74e-03 |
0.00980 |
| 5.62 |
420000 |
0.7200 |
0.00294 |
0.00145 |
9.26e-05 |
0.00578 |
| 5.72 |
529000 |
0.8660 |
0.00243 |
0.00157 |
-6.56e-04 |
0.00551 |
VE scale (1 minus risk / placebo risk) (monotone)

| 3.32 |
2100 |
0.314 |
0.157 |
0.00595 |
0.622 |
| 3.42 |
2650 |
0.314 |
0.182 |
-0.04310 |
0.671 |
| 3.52 |
3340 |
0.314 |
0.182 |
-0.04310 |
0.671 |
| 3.62 |
4200 |
0.314 |
0.182 |
-0.04310 |
0.671 |
| 3.72 |
5290 |
0.314 |
0.184 |
-0.04680 |
0.674 |
| 3.82 |
6660 |
0.314 |
0.184 |
-0.04720 |
0.675 |
| 3.92 |
8380 |
0.314 |
0.184 |
-0.04750 |
0.675 |
| 4.02 |
10500 |
0.314 |
0.187 |
-0.05240 |
0.680 |
| 4.12 |
13300 |
0.314 |
0.187 |
-0.05240 |
0.680 |
| 4.22 |
16700 |
0.314 |
0.186 |
-0.05100 |
0.679 |
| 4.32 |
21000 |
0.314 |
0.186 |
-0.05100 |
0.679 |
| 4.42 |
26500 |
0.314 |
0.186 |
-0.05080 |
0.678 |
| 4.52 |
33400 |
0.314 |
0.187 |
-0.05330 |
0.681 |
| 4.62 |
42000 |
0.314 |
0.190 |
-0.05940 |
0.687 |
| 4.72 |
52900 |
0.314 |
0.191 |
-0.06010 |
0.688 |
| 4.82 |
66600 |
0.314 |
0.191 |
-0.06090 |
0.689 |
| 4.92 |
83800 |
0.314 |
0.202 |
-0.08260 |
0.710 |
| 5.02 |
105000 |
0.314 |
0.200 |
-0.07830 |
0.706 |
| 5.12 |
133000 |
0.314 |
0.207 |
-0.09140 |
0.719 |
| 5.22 |
167000 |
0.314 |
0.226 |
-0.12800 |
0.756 |
| 5.32 |
210000 |
0.314 |
0.232 |
-0.14000 |
0.768 |
| 5.42 |
265000 |
0.360 |
0.236 |
-0.10200 |
0.822 |
| 5.52 |
334000 |
0.360 |
0.249 |
-0.12700 |
0.847 |
| 5.62 |
420000 |
0.674 |
0.169 |
0.34400 |
1.000 |
| 5.72 |
529000 |
0.731 |
0.179 |
0.37900 |
1.080 |
Placebo
Not monotone

| 2.4 |
252 |
0.00902 |
0.001390 |
0.006290 |
0.01170 |
| 2.5 |
317 |
0.00952 |
0.001960 |
0.005670 |
0.01340 |
| 2.6 |
399 |
0.00952 |
0.001960 |
0.005670 |
0.01340 |
| 2.7 |
503 |
0.00952 |
0.001960 |
0.005670 |
0.01340 |
| 2.8 |
633 |
0.00924 |
0.001930 |
0.005470 |
0.01300 |
| 2.9 |
796 |
0.00925 |
0.001930 |
0.005470 |
0.01300 |
| 3.0 |
1000 |
0.00932 |
0.001940 |
0.005510 |
0.01310 |
| 3.1 |
1260 |
0.00949 |
0.001980 |
0.005610 |
0.01340 |
| 3.2 |
1590 |
0.00894 |
0.001910 |
0.005200 |
0.01270 |
| 3.3 |
2000 |
0.00867 |
0.001870 |
0.004990 |
0.01230 |
| 3.4 |
2520 |
0.00833 |
0.001860 |
0.004690 |
0.01200 |
| 3.5 |
3170 |
0.00814 |
0.001840 |
0.004530 |
0.01180 |
| 3.6 |
3990 |
0.00822 |
0.001860 |
0.004570 |
0.01190 |
| 3.7 |
5030 |
0.00706 |
0.001700 |
0.003730 |
0.01040 |
| 3.8 |
6330 |
0.00660 |
0.001640 |
0.003380 |
0.00981 |
| 3.9 |
7960 |
0.00582 |
0.001580 |
0.002730 |
0.00891 |
| 4.0 |
10000 |
0.00597 |
0.001630 |
0.002780 |
0.00917 |
| 4.1 |
12600 |
0.00449 |
0.001410 |
0.001730 |
0.00725 |
| 4.2 |
15900 |
0.00416 |
0.001430 |
0.001350 |
0.00696 |
| 4.3 |
20000 |
0.00371 |
0.001340 |
0.001090 |
0.00633 |
| 4.4 |
25200 |
0.00314 |
0.001270 |
0.000653 |
0.00563 |
| 4.5 |
31700 |
0.00263 |
0.001140 |
0.000389 |
0.00486 |
| 4.6 |
39900 |
0.00284 |
0.001250 |
0.000383 |
0.00529 |
| 4.7 |
50300 |
0.00209 |
0.001160 |
-0.000188 |
0.00436 |
| 4.8 |
63300 |
0.00149 |
0.000941 |
-0.000357 |
0.00333 |
Monotone

| 2.4 |
252 |
0.0000 |
0.00939 |
0.001390 |
0.006660 |
0.01210 |
| 2.5 |
317 |
0.0153 |
0.00939 |
0.001960 |
0.005540 |
0.01320 |
| 2.6 |
399 |
0.0153 |
0.00939 |
0.001960 |
0.005540 |
0.01320 |
| 2.7 |
503 |
0.0153 |
0.00939 |
0.001960 |
0.005540 |
0.01320 |
| 2.8 |
633 |
0.0161 |
0.00932 |
0.001930 |
0.005550 |
0.01310 |
| 2.9 |
796 |
0.0166 |
0.00932 |
0.001930 |
0.005550 |
0.01310 |
| 3.0 |
1000 |
0.0216 |
0.00932 |
0.001940 |
0.005520 |
0.01310 |
| 3.1 |
1260 |
0.0488 |
0.00932 |
0.001980 |
0.005440 |
0.01320 |
| 3.2 |
1590 |
0.0518 |
0.00894 |
0.001910 |
0.005200 |
0.01270 |
| 3.3 |
2000 |
0.0546 |
0.00867 |
0.001870 |
0.004990 |
0.01230 |
| 3.4 |
2520 |
0.0884 |
0.00833 |
0.001860 |
0.004690 |
0.01200 |
| 3.5 |
3170 |
0.1130 |
0.00818 |
0.001840 |
0.004570 |
0.01180 |
| 3.6 |
3990 |
0.1190 |
0.00818 |
0.001860 |
0.004530 |
0.01180 |
| 3.7 |
5030 |
0.1220 |
0.00706 |
0.001700 |
0.003730 |
0.01040 |
| 3.8 |
6330 |
0.1740 |
0.00660 |
0.001640 |
0.003380 |
0.00981 |
| 3.9 |
7960 |
0.2180 |
0.00590 |
0.001580 |
0.002800 |
0.00899 |
| 4.0 |
10000 |
0.2460 |
0.00590 |
0.001630 |
0.002700 |
0.00909 |
| 4.1 |
12600 |
0.3120 |
0.00449 |
0.001410 |
0.001730 |
0.00725 |
| 4.2 |
15900 |
0.3770 |
0.00416 |
0.001430 |
0.001350 |
0.00696 |
| 4.3 |
20000 |
0.4060 |
0.00371 |
0.001340 |
0.001090 |
0.00633 |
| 4.4 |
25200 |
0.4490 |
0.00314 |
0.001270 |
0.000653 |
0.00563 |
| 4.5 |
31700 |
0.4770 |
0.00273 |
0.001140 |
0.000494 |
0.00497 |
| 4.6 |
39900 |
0.5440 |
0.00273 |
0.001250 |
0.000277 |
0.00519 |
| 4.7 |
50300 |
0.5930 |
0.00209 |
0.001160 |
-0.000188 |
0.00436 |
| 4.8 |
63300 |
0.6110 |
0.00149 |
0.000941 |
-0.000357 |
0.00333 |
Vaccine (change)
Unscaled (not monotone)

| -1.0300 |
0.093 |
0.00584 |
0.00131 |
0.003280 |
0.00841 |
| -0.9320 |
0.117 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.8320 |
0.147 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.7320 |
0.186 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.6320 |
0.234 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.5320 |
0.294 |
0.00599 |
0.00136 |
0.003320 |
0.00866 |
| -0.4320 |
0.370 |
0.00603 |
0.00138 |
0.003330 |
0.00874 |
| -0.3320 |
0.466 |
0.00608 |
0.00137 |
0.003390 |
0.00876 |
| -0.2320 |
0.587 |
0.00608 |
0.00137 |
0.003390 |
0.00876 |
| -0.1320 |
0.739 |
0.00622 |
0.00141 |
0.003450 |
0.00899 |
| -0.0315 |
0.930 |
0.00622 |
0.00141 |
0.003450 |
0.00899 |
| 0.0685 |
1.170 |
0.00605 |
0.00140 |
0.003300 |
0.00880 |
| 0.1680 |
1.470 |
0.00584 |
0.00137 |
0.003140 |
0.00853 |
| 0.2680 |
1.860 |
0.00597 |
0.00142 |
0.003190 |
0.00875 |
| 0.3680 |
2.340 |
0.00607 |
0.00145 |
0.003220 |
0.00891 |
| 0.4680 |
2.940 |
0.00616 |
0.00147 |
0.003270 |
0.00905 |
| 0.5680 |
3.700 |
0.00615 |
0.00152 |
0.003180 |
0.00913 |
| 0.6680 |
4.660 |
0.00683 |
0.00180 |
0.003310 |
0.01040 |
| 0.7680 |
5.870 |
0.00736 |
0.00206 |
0.003330 |
0.01140 |
| 0.8680 |
7.390 |
0.00758 |
0.00206 |
0.003550 |
0.01160 |
| 0.9680 |
9.300 |
0.00832 |
0.00224 |
0.003920 |
0.01270 |
| 1.0700 |
11.700 |
0.00790 |
0.00217 |
0.003650 |
0.01220 |
| 1.1700 |
14.700 |
0.00738 |
0.00207 |
0.003320 |
0.01140 |
| 1.2700 |
18.600 |
0.00953 |
0.00297 |
0.003710 |
0.01530 |
| 1.3700 |
23.400 |
0.00827 |
0.00257 |
0.003230 |
0.01330 |
| 1.4700 |
29.400 |
0.00821 |
0.00278 |
0.002760 |
0.01370 |
| 1.5700 |
37.000 |
0.00726 |
0.00264 |
0.002090 |
0.01240 |
| 1.6700 |
46.600 |
0.00694 |
0.00283 |
0.001380 |
0.01250 |
| 1.7700 |
58.700 |
0.00775 |
0.00340 |
0.001090 |
0.01440 |
| 1.8700 |
73.900 |
0.00791 |
0.00365 |
0.000755 |
0.01510 |
| 1.9700 |
93.000 |
0.00865 |
0.00413 |
0.000566 |
0.01670 |
| 2.0700 |
117.000 |
0.01160 |
0.00573 |
0.000404 |
0.02290 |
| 2.1700 |
147.000 |
0.01030 |
0.00749 |
-0.004340 |
0.02500 |
Unscaled (monotone)

| -1.0300 |
0.093 |
0.00000 |
0.00662 |
0.00131 |
4.05e-03 |
0.00918 |
| -0.9320 |
0.117 |
0.00692 |
0.00662 |
0.00133 |
4.01e-03 |
0.00922 |
| -0.8320 |
0.147 |
0.00692 |
0.00662 |
0.00133 |
4.01e-03 |
0.00922 |
| -0.7320 |
0.186 |
0.00692 |
0.00662 |
0.00133 |
4.01e-03 |
0.00922 |
| -0.6320 |
0.234 |
0.00692 |
0.00662 |
0.00133 |
4.01e-03 |
0.00922 |
| -0.5320 |
0.294 |
0.01380 |
0.00662 |
0.00136 |
3.95e-03 |
0.00929 |
| -0.4320 |
0.370 |
0.01970 |
0.00662 |
0.00138 |
3.91e-03 |
0.00932 |
| -0.3320 |
0.466 |
0.03510 |
0.00662 |
0.00137 |
3.93e-03 |
0.00930 |
| -0.2320 |
0.587 |
0.03560 |
0.00662 |
0.00137 |
3.93e-03 |
0.00930 |
| -0.1320 |
0.739 |
0.06170 |
0.00662 |
0.00141 |
3.84e-03 |
0.00939 |
| -0.0315 |
0.930 |
0.06230 |
0.00662 |
0.00141 |
3.84e-03 |
0.00939 |
| 0.0685 |
1.170 |
0.08610 |
0.00662 |
0.00140 |
3.87e-03 |
0.00936 |
| 0.1680 |
1.470 |
0.09910 |
0.00662 |
0.00137 |
3.92e-03 |
0.00931 |
| 0.2680 |
1.860 |
0.11900 |
0.00662 |
0.00142 |
3.84e-03 |
0.00939 |
| 0.3680 |
2.340 |
0.13300 |
0.00662 |
0.00145 |
3.77e-03 |
0.00946 |
| 0.4680 |
2.940 |
0.15300 |
0.00662 |
0.00147 |
3.73e-03 |
0.00951 |
| 0.5680 |
3.700 |
0.19200 |
0.00662 |
0.00152 |
3.64e-03 |
0.00959 |
| 0.6680 |
4.660 |
0.24300 |
0.00662 |
0.00180 |
3.09e-03 |
0.01010 |
| 0.7680 |
5.870 |
0.28300 |
0.00662 |
0.00206 |
2.59e-03 |
0.01060 |
| 0.8680 |
7.390 |
0.32700 |
0.00662 |
0.00206 |
2.58e-03 |
0.01060 |
| 0.9680 |
9.300 |
0.34400 |
0.00662 |
0.00224 |
2.22e-03 |
0.01100 |
| 1.0700 |
11.700 |
0.35100 |
0.00662 |
0.00217 |
2.37e-03 |
0.01090 |
| 1.1700 |
14.700 |
0.40300 |
0.00662 |
0.00207 |
2.55e-03 |
0.01070 |
| 1.2700 |
18.600 |
0.47200 |
0.00662 |
0.00297 |
8.01e-04 |
0.01240 |
| 1.3700 |
23.400 |
0.50500 |
0.00662 |
0.00257 |
1.57e-03 |
0.01170 |
| 1.4700 |
29.400 |
0.59000 |
0.00662 |
0.00278 |
1.16e-03 |
0.01210 |
| 1.5700 |
37.000 |
0.61500 |
0.00662 |
0.00264 |
1.44e-03 |
0.01180 |
| 1.6700 |
46.600 |
0.65600 |
0.00662 |
0.00283 |
1.06e-03 |
0.01220 |
| 1.7700 |
58.700 |
0.71500 |
0.00662 |
0.00340 |
-5.07e-05 |
0.01330 |
| 1.8700 |
73.900 |
0.76200 |
0.00662 |
0.00365 |
-5.38e-04 |
0.01380 |
| 1.9700 |
93.000 |
0.79900 |
0.00662 |
0.00413 |
-1.47e-03 |
0.01470 |
| 2.0700 |
117.000 |
0.83000 |
0.00662 |
0.00573 |
-4.61e-03 |
0.01780 |
| 2.1700 |
147.000 |
0.90000 |
0.00662 |
0.00749 |
-8.06e-03 |
0.02130 |
VE scale (1 minus risk / placebo risk) (monotone)

| -1.0300 |
0.093 |
0.266 |
0.180 |
-0.0862 |
0.619 |
| -0.9320 |
0.117 |
0.266 |
0.183 |
-0.0921 |
0.625 |
| -0.8320 |
0.147 |
0.266 |
0.183 |
-0.0921 |
0.625 |
| -0.7320 |
0.186 |
0.266 |
0.183 |
-0.0921 |
0.625 |
| -0.6320 |
0.234 |
0.266 |
0.183 |
-0.0921 |
0.625 |
| -0.5320 |
0.294 |
0.266 |
0.187 |
-0.1010 |
0.634 |
| -0.4320 |
0.370 |
0.266 |
0.190 |
-0.1050 |
0.638 |
| -0.3320 |
0.466 |
0.266 |
0.188 |
-0.1030 |
0.636 |
| -0.2320 |
0.587 |
0.266 |
0.188 |
-0.1030 |
0.635 |
| -0.1320 |
0.739 |
0.266 |
0.195 |
-0.1150 |
0.648 |
| -0.0315 |
0.930 |
0.266 |
0.195 |
-0.1150 |
0.648 |
| 0.0685 |
1.170 |
0.266 |
0.193 |
-0.1110 |
0.644 |
| 0.1680 |
1.470 |
0.266 |
0.189 |
-0.1040 |
0.636 |
| 0.2680 |
1.860 |
0.266 |
0.195 |
-0.1160 |
0.648 |
| 0.3680 |
2.340 |
0.266 |
0.199 |
-0.1250 |
0.657 |
| 0.4680 |
2.940 |
0.266 |
0.203 |
-0.1310 |
0.664 |
| 0.5680 |
3.700 |
0.266 |
0.209 |
-0.1430 |
0.675 |
| 0.6680 |
4.660 |
0.266 |
0.247 |
-0.2180 |
0.751 |
| 0.7680 |
5.870 |
0.266 |
0.283 |
-0.2880 |
0.820 |
| 0.8680 |
7.390 |
0.266 |
0.283 |
-0.2880 |
0.821 |
| 0.9680 |
9.300 |
0.266 |
0.309 |
-0.3390 |
0.871 |
| 1.0700 |
11.700 |
0.266 |
0.298 |
-0.3180 |
0.851 |
| 1.1700 |
14.700 |
0.266 |
0.285 |
-0.2930 |
0.825 |
| 1.2700 |
18.600 |
0.266 |
0.408 |
-0.5330 |
1.070 |
| 1.3700 |
23.400 |
0.266 |
0.354 |
-0.4280 |
0.960 |
| 1.4700 |
29.400 |
0.266 |
0.383 |
-0.4840 |
1.020 |
| 1.5700 |
37.000 |
0.266 |
0.363 |
-0.4460 |
0.979 |
| 1.6700 |
46.600 |
0.266 |
0.390 |
-0.4970 |
1.030 |
| 1.7700 |
58.700 |
0.266 |
0.468 |
-0.6510 |
1.180 |
| 1.8700 |
73.900 |
0.266 |
0.502 |
-0.7180 |
1.250 |
| 1.9700 |
93.000 |
0.266 |
0.568 |
-0.8460 |
1.380 |
| 2.0700 |
117.000 |
0.266 |
0.788 |
-1.2800 |
1.810 |
| 2.1700 |
147.000 |
0.266 |
1.030 |
-1.7500 |
2.280 |
IgG Spike Beta
Vaccine
Unscaled (not monotone)

| 3.15 |
1400 |
0.00522 |
0.00105 |
0.003170 |
0.00727 |
| 3.25 |
1760 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.35 |
2210 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.45 |
2790 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.55 |
3510 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.65 |
4420 |
0.00599 |
0.00136 |
0.003330 |
0.00865 |
| 3.75 |
5560 |
0.00599 |
0.00136 |
0.003330 |
0.00866 |
| 3.85 |
7000 |
0.00599 |
0.00136 |
0.003330 |
0.00866 |
| 3.95 |
8810 |
0.00601 |
0.00136 |
0.003360 |
0.00867 |
| 4.05 |
11100 |
0.00610 |
0.00139 |
0.003370 |
0.00882 |
| 4.15 |
14000 |
0.00617 |
0.00142 |
0.003380 |
0.00896 |
| 4.25 |
17600 |
0.00626 |
0.00145 |
0.003420 |
0.00911 |
| 4.35 |
22100 |
0.00630 |
0.00145 |
0.003460 |
0.00915 |
| 4.45 |
27900 |
0.00630 |
0.00145 |
0.003470 |
0.00914 |
| 4.55 |
35100 |
0.00635 |
0.00143 |
0.003540 |
0.00916 |
| 4.65 |
44200 |
0.00643 |
0.00145 |
0.003590 |
0.00928 |
| 4.75 |
55600 |
0.00657 |
0.00149 |
0.003660 |
0.00949 |
| 4.85 |
70000 |
0.00708 |
0.00163 |
0.003890 |
0.01030 |
| 4.95 |
88100 |
0.00687 |
0.00161 |
0.003720 |
0.01000 |
| 5.05 |
111000 |
0.00706 |
0.00167 |
0.003790 |
0.01030 |
| 5.15 |
140000 |
0.00733 |
0.00183 |
0.003740 |
0.01090 |
| 5.25 |
176000 |
0.00603 |
0.00170 |
0.002700 |
0.00937 |
| 5.35 |
221000 |
0.00712 |
0.00217 |
0.002880 |
0.01140 |
| 5.45 |
279000 |
0.00523 |
0.00189 |
0.001520 |
0.00893 |
| 5.55 |
351000 |
0.00467 |
0.00221 |
0.000337 |
0.00900 |
| 5.65 |
442000 |
0.00211 |
0.00129 |
-0.000428 |
0.00464 |
Unscaled (monotone)

| 3.15 |
1400 |
0.0000 |
0.00628 |
0.00105 |
0.004230 |
0.00833 |
| 3.25 |
1760 |
0.0117 |
0.00628 |
0.00134 |
0.003660 |
0.00889 |
| 3.35 |
2210 |
0.0117 |
0.00628 |
0.00134 |
0.003660 |
0.00889 |
| 3.45 |
2790 |
0.0117 |
0.00628 |
0.00134 |
0.003660 |
0.00889 |
| 3.55 |
3510 |
0.0117 |
0.00628 |
0.00134 |
0.003660 |
0.00889 |
| 3.65 |
4420 |
0.0175 |
0.00628 |
0.00136 |
0.003620 |
0.00893 |
| 3.75 |
5560 |
0.0180 |
0.00628 |
0.00136 |
0.003610 |
0.00894 |
| 3.85 |
7000 |
0.0180 |
0.00628 |
0.00136 |
0.003610 |
0.00894 |
| 3.95 |
8810 |
0.0255 |
0.00628 |
0.00136 |
0.003620 |
0.00894 |
| 4.05 |
11100 |
0.0324 |
0.00628 |
0.00139 |
0.003550 |
0.00900 |
| 4.15 |
14000 |
0.0393 |
0.00628 |
0.00142 |
0.003490 |
0.00906 |
| 4.25 |
17600 |
0.0515 |
0.00628 |
0.00145 |
0.003430 |
0.00912 |
| 4.35 |
22100 |
0.0637 |
0.00628 |
0.00145 |
0.003430 |
0.00912 |
| 4.45 |
27900 |
0.0648 |
0.00628 |
0.00145 |
0.003440 |
0.00912 |
| 4.55 |
35100 |
0.0865 |
0.00628 |
0.00143 |
0.003470 |
0.00909 |
| 4.65 |
44200 |
0.1050 |
0.00628 |
0.00145 |
0.003430 |
0.00912 |
| 4.75 |
55600 |
0.1310 |
0.00628 |
0.00149 |
0.003360 |
0.00919 |
| 4.85 |
70000 |
0.1770 |
0.00628 |
0.00163 |
0.003090 |
0.00947 |
| 4.95 |
88100 |
0.1910 |
0.00628 |
0.00161 |
0.003130 |
0.00942 |
| 5.05 |
111000 |
0.2110 |
0.00628 |
0.00167 |
0.003010 |
0.00955 |
| 5.15 |
140000 |
0.2690 |
0.00628 |
0.00183 |
0.002690 |
0.00987 |
| 5.25 |
176000 |
0.3230 |
0.00628 |
0.00170 |
0.002940 |
0.00961 |
| 5.35 |
221000 |
0.5070 |
0.00628 |
0.00217 |
0.002030 |
0.01050 |
| 5.45 |
279000 |
0.6150 |
0.00523 |
0.00189 |
0.001520 |
0.00893 |
| 5.55 |
351000 |
0.6950 |
0.00467 |
0.00221 |
0.000337 |
0.00900 |
| 5.65 |
442000 |
0.8090 |
0.00211 |
0.00129 |
-0.000428 |
0.00464 |
VE scale (1 minus risk / placebo risk) (monotone)

| 3.15 |
1400 |
0.304 |
0.158 |
-0.00589 |
0.614 |
| 3.25 |
1760 |
0.304 |
0.183 |
-0.05460 |
0.663 |
| 3.35 |
2210 |
0.304 |
0.183 |
-0.05460 |
0.663 |
| 3.45 |
2790 |
0.304 |
0.183 |
-0.05460 |
0.663 |
| 3.55 |
3510 |
0.304 |
0.183 |
-0.05460 |
0.663 |
| 3.65 |
4420 |
0.304 |
0.185 |
-0.05830 |
0.666 |
| 3.75 |
5560 |
0.304 |
0.185 |
-0.05870 |
0.667 |
| 3.85 |
7000 |
0.304 |
0.185 |
-0.05870 |
0.667 |
| 3.95 |
8810 |
0.304 |
0.185 |
-0.05840 |
0.666 |
| 4.05 |
11100 |
0.304 |
0.188 |
-0.06400 |
0.672 |
| 4.15 |
14000 |
0.304 |
0.191 |
-0.07010 |
0.678 |
| 4.25 |
17600 |
0.304 |
0.194 |
-0.07550 |
0.683 |
| 4.35 |
22100 |
0.304 |
0.193 |
-0.07510 |
0.683 |
| 4.45 |
27900 |
0.304 |
0.193 |
-0.07480 |
0.683 |
| 4.55 |
35100 |
0.304 |
0.192 |
-0.07220 |
0.680 |
| 4.65 |
44200 |
0.304 |
0.194 |
-0.07550 |
0.683 |
| 4.75 |
55600 |
0.304 |
0.197 |
-0.08200 |
0.690 |
| 4.85 |
70000 |
0.304 |
0.210 |
-0.10800 |
0.716 |
| 4.95 |
88100 |
0.304 |
0.208 |
-0.10400 |
0.712 |
| 5.05 |
111000 |
0.304 |
0.214 |
-0.11500 |
0.723 |
| 5.15 |
140000 |
0.304 |
0.230 |
-0.14600 |
0.754 |
| 5.25 |
176000 |
0.304 |
0.217 |
-0.12200 |
0.730 |
| 5.35 |
221000 |
0.304 |
0.263 |
-0.21200 |
0.820 |
| 5.45 |
279000 |
0.421 |
0.228 |
-0.02640 |
0.867 |
| 5.55 |
351000 |
0.482 |
0.258 |
-0.02270 |
0.988 |
| 5.65 |
442000 |
0.766 |
0.148 |
0.47700 |
1.060 |
Placebo
Not monotone

| 2.4 |
252 |
0.00902 |
0.00139 |
0.006290 |
0.01170 |
| 2.5 |
317 |
0.00918 |
0.00192 |
0.005420 |
0.01290 |
| 2.6 |
399 |
0.00918 |
0.00192 |
0.005420 |
0.01290 |
| 2.7 |
503 |
0.00918 |
0.00192 |
0.005420 |
0.01290 |
| 2.8 |
633 |
0.00918 |
0.00192 |
0.005420 |
0.01290 |
| 2.9 |
796 |
0.00918 |
0.00192 |
0.005430 |
0.01290 |
| 3.0 |
1000 |
0.00923 |
0.00194 |
0.005440 |
0.01300 |
| 3.1 |
1260 |
0.00894 |
0.00191 |
0.005200 |
0.01270 |
| 3.2 |
1590 |
0.00867 |
0.00187 |
0.005000 |
0.01230 |
| 3.3 |
2000 |
0.00784 |
0.00176 |
0.004380 |
0.01130 |
| 3.4 |
2520 |
0.00805 |
0.00182 |
0.004480 |
0.01160 |
| 3.5 |
3170 |
0.00755 |
0.00176 |
0.004100 |
0.01100 |
| 3.6 |
3990 |
0.00684 |
0.00167 |
0.003560 |
0.01010 |
| 3.7 |
5030 |
0.00717 |
0.00175 |
0.003730 |
0.01060 |
| 3.8 |
6330 |
0.00710 |
0.00178 |
0.003620 |
0.01060 |
| 3.9 |
7960 |
0.00488 |
0.00144 |
0.002060 |
0.00770 |
| 4.0 |
10000 |
0.00418 |
0.00135 |
0.001540 |
0.00682 |
| 4.1 |
12600 |
0.00464 |
0.00153 |
0.001650 |
0.00763 |
| 4.2 |
15900 |
0.00355 |
0.00135 |
0.000909 |
0.00620 |
| 4.3 |
20000 |
0.00318 |
0.00129 |
0.000657 |
0.00571 |
| 4.4 |
25200 |
0.00228 |
0.00110 |
0.000129 |
0.00443 |
| 4.5 |
31700 |
0.00185 |
0.00100 |
-0.000112 |
0.00381 |
| 4.6 |
39900 |
0.00196 |
0.00110 |
-0.000195 |
0.00411 |
Monotone

| 2.4 |
252 |
0.00000 |
0.00916 |
0.00139 |
6.43e-03 |
0.01190 |
| 2.5 |
317 |
0.00330 |
0.00916 |
0.00192 |
5.41e-03 |
0.01290 |
| 2.6 |
399 |
0.00330 |
0.00916 |
0.00192 |
5.41e-03 |
0.01290 |
| 2.7 |
503 |
0.00330 |
0.00916 |
0.00192 |
5.41e-03 |
0.01290 |
| 2.8 |
633 |
0.00330 |
0.00916 |
0.00192 |
5.41e-03 |
0.01290 |
| 2.9 |
796 |
0.00380 |
0.00916 |
0.00192 |
5.41e-03 |
0.01290 |
| 3.0 |
1000 |
0.00928 |
0.00916 |
0.00194 |
5.36e-03 |
0.01300 |
| 3.1 |
1260 |
0.04980 |
0.00894 |
0.00191 |
5.20e-03 |
0.01270 |
| 3.2 |
1590 |
0.05260 |
0.00867 |
0.00187 |
5.00e-03 |
0.01230 |
| 3.3 |
2000 |
0.06100 |
0.00794 |
0.00176 |
4.49e-03 |
0.01140 |
| 3.4 |
2520 |
0.09200 |
0.00794 |
0.00182 |
4.37e-03 |
0.01150 |
| 3.5 |
3170 |
0.10200 |
0.00755 |
0.00176 |
4.10e-03 |
0.01100 |
| 3.6 |
3990 |
0.14600 |
0.00704 |
0.00167 |
3.76e-03 |
0.01030 |
| 3.7 |
5030 |
0.18500 |
0.00704 |
0.00175 |
3.60e-03 |
0.01050 |
| 3.8 |
6330 |
0.20900 |
0.00704 |
0.00178 |
3.55e-03 |
0.01050 |
| 3.9 |
7960 |
0.23700 |
0.00488 |
0.00144 |
2.06e-03 |
0.00770 |
| 4.0 |
10000 |
0.32300 |
0.00440 |
0.00135 |
1.77e-03 |
0.00704 |
| 4.1 |
12600 |
0.41900 |
0.00440 |
0.00153 |
1.41e-03 |
0.00740 |
| 4.2 |
15900 |
0.44200 |
0.00355 |
0.00135 |
9.09e-04 |
0.00620 |
| 4.3 |
20000 |
0.45900 |
0.00318 |
0.00129 |
6.57e-04 |
0.00571 |
| 4.4 |
25200 |
0.49700 |
0.00228 |
0.00110 |
1.29e-04 |
0.00443 |
| 4.5 |
31700 |
0.54900 |
0.00190 |
0.00100 |
-5.75e-05 |
0.00386 |
| 4.6 |
39900 |
0.58700 |
0.00190 |
0.00110 |
-2.49e-04 |
0.00406 |
Vaccine (change)
Unscaled (not monotone)

| -1.1500 |
0.0701 |
0.00584 |
0.00131 |
0.003280 |
0.00841 |
| -1.0500 |
0.0882 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.9550 |
0.1110 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.8550 |
0.1400 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.7550 |
0.1760 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.6550 |
0.2220 |
0.00599 |
0.00136 |
0.003320 |
0.00866 |
| -0.5550 |
0.2790 |
0.00599 |
0.00136 |
0.003320 |
0.00866 |
| -0.4550 |
0.3510 |
0.00603 |
0.00138 |
0.003330 |
0.00874 |
| -0.3550 |
0.4420 |
0.00606 |
0.00137 |
0.003380 |
0.00875 |
| -0.2550 |
0.5560 |
0.00606 |
0.00137 |
0.003380 |
0.00875 |
| -0.1550 |
0.7010 |
0.00612 |
0.00139 |
0.003400 |
0.00883 |
| -0.0545 |
0.8820 |
0.00619 |
0.00140 |
0.003450 |
0.00894 |
| 0.0455 |
1.1100 |
0.00622 |
0.00140 |
0.003460 |
0.00897 |
| 0.1450 |
1.4000 |
0.00577 |
0.00136 |
0.003110 |
0.00842 |
| 0.2450 |
1.7600 |
0.00583 |
0.00137 |
0.003140 |
0.00852 |
| 0.3450 |
2.2200 |
0.00595 |
0.00141 |
0.003190 |
0.00871 |
| 0.4450 |
2.7900 |
0.00581 |
0.00141 |
0.003040 |
0.00858 |
| 0.5450 |
3.5100 |
0.00603 |
0.00147 |
0.003140 |
0.00892 |
| 0.6450 |
4.4200 |
0.00635 |
0.00157 |
0.003260 |
0.00943 |
| 0.7450 |
5.5600 |
0.00680 |
0.00177 |
0.003320 |
0.01030 |
| 0.8450 |
7.0100 |
0.00734 |
0.00196 |
0.003500 |
0.01120 |
| 0.9450 |
8.8200 |
0.00717 |
0.00198 |
0.003280 |
0.01110 |
| 1.0500 |
11.1000 |
0.00708 |
0.00205 |
0.003060 |
0.01110 |
| 1.1500 |
14.0000 |
0.00801 |
0.00232 |
0.003470 |
0.01260 |
| 1.2500 |
17.6000 |
0.00772 |
0.00227 |
0.003260 |
0.01220 |
| 1.3500 |
22.2000 |
0.00759 |
0.00231 |
0.003060 |
0.01210 |
| 1.4500 |
27.9000 |
0.00732 |
0.00244 |
0.002540 |
0.01210 |
| 1.5500 |
35.1000 |
0.00525 |
0.00208 |
0.001180 |
0.00932 |
| 1.6500 |
44.2000 |
0.00576 |
0.00230 |
0.001250 |
0.01030 |
| 1.7500 |
55.6000 |
0.00581 |
0.00277 |
0.000378 |
0.01120 |
| 1.8500 |
70.1000 |
0.00632 |
0.00351 |
-0.000559 |
0.01320 |
| 1.9500 |
88.2000 |
0.00711 |
0.00536 |
-0.003400 |
0.01760 |
| 2.0500 |
111.0000 |
0.00686 |
0.00543 |
-0.003780 |
0.01750 |
| 2.1500 |
140.0000 |
0.01220 |
0.00668 |
-0.000879 |
0.02530 |
| 2.2500 |
176.0000 |
0.01350 |
0.00763 |
-0.001490 |
0.02840 |
Unscaled (monotone)

| -1.1500 |
0.0701 |
0.00000 |
0.00635 |
0.00131 |
0.003790 |
0.00892 |
| -1.0500 |
0.0882 |
0.00692 |
0.00635 |
0.00133 |
0.003750 |
0.00896 |
| -0.9550 |
0.1110 |
0.00692 |
0.00635 |
0.00133 |
0.003750 |
0.00896 |
| -0.8550 |
0.1400 |
0.00692 |
0.00635 |
0.00133 |
0.003750 |
0.00896 |
| -0.7550 |
0.1760 |
0.00692 |
0.00635 |
0.00133 |
0.003750 |
0.00896 |
| -0.6550 |
0.2220 |
0.01380 |
0.00635 |
0.00136 |
0.003680 |
0.00902 |
| -0.5550 |
0.2790 |
0.01380 |
0.00635 |
0.00136 |
0.003680 |
0.00902 |
| -0.4550 |
0.3510 |
0.01970 |
0.00635 |
0.00138 |
0.003650 |
0.00906 |
| -0.3550 |
0.4420 |
0.02920 |
0.00635 |
0.00137 |
0.003670 |
0.00904 |
| -0.2550 |
0.5560 |
0.02920 |
0.00635 |
0.00137 |
0.003670 |
0.00904 |
| -0.1550 |
0.7010 |
0.04110 |
0.00635 |
0.00139 |
0.003640 |
0.00907 |
| -0.0545 |
0.8820 |
0.06810 |
0.00635 |
0.00140 |
0.003610 |
0.00910 |
| 0.0455 |
1.1100 |
0.07450 |
0.00635 |
0.00140 |
0.003600 |
0.00911 |
| 0.1450 |
1.4000 |
0.08760 |
0.00635 |
0.00136 |
0.003700 |
0.00901 |
| 0.2450 |
1.7600 |
0.09930 |
0.00635 |
0.00137 |
0.003660 |
0.00904 |
| 0.3450 |
2.2200 |
0.12100 |
0.00635 |
0.00141 |
0.003590 |
0.00912 |
| 0.4450 |
2.7900 |
0.14900 |
0.00635 |
0.00141 |
0.003580 |
0.00912 |
| 0.5450 |
3.5100 |
0.18000 |
0.00635 |
0.00147 |
0.003460 |
0.00924 |
| 0.6450 |
4.4200 |
0.22700 |
0.00635 |
0.00157 |
0.003270 |
0.00944 |
| 0.7450 |
5.5600 |
0.25000 |
0.00635 |
0.00177 |
0.002880 |
0.00983 |
| 0.8450 |
7.0100 |
0.31100 |
0.00635 |
0.00196 |
0.002510 |
0.01020 |
| 0.9450 |
8.8200 |
0.32100 |
0.00635 |
0.00198 |
0.002460 |
0.01020 |
| 1.0500 |
11.1000 |
0.34800 |
0.00635 |
0.00205 |
0.002330 |
0.01040 |
| 1.1500 |
14.0000 |
0.38400 |
0.00635 |
0.00232 |
0.001810 |
0.01090 |
| 1.2500 |
17.6000 |
0.39400 |
0.00635 |
0.00227 |
0.001900 |
0.01080 |
| 1.3500 |
22.2000 |
0.48200 |
0.00635 |
0.00231 |
0.001820 |
0.01090 |
| 1.4500 |
27.9000 |
0.55700 |
0.00635 |
0.00244 |
0.001570 |
0.01110 |
| 1.5500 |
35.1000 |
0.57300 |
0.00635 |
0.00208 |
0.002280 |
0.01040 |
| 1.6500 |
44.2000 |
0.62200 |
0.00635 |
0.00230 |
0.001840 |
0.01090 |
| 1.7500 |
55.6000 |
0.68800 |
0.00635 |
0.00277 |
0.000922 |
0.01180 |
| 1.8500 |
70.1000 |
0.75200 |
0.00635 |
0.00351 |
-0.000523 |
0.01320 |
| 1.9500 |
88.2000 |
0.78700 |
0.00635 |
0.00536 |
-0.004160 |
0.01690 |
| 2.0500 |
111.0000 |
0.84500 |
0.00635 |
0.00543 |
-0.004280 |
0.01700 |
| 2.1500 |
140.0000 |
0.89200 |
0.00635 |
0.00668 |
-0.006740 |
0.01940 |
| 2.2500 |
176.0000 |
0.91300 |
0.00635 |
0.00763 |
-0.008600 |
0.02130 |
VE scale (1 minus risk / placebo risk) (monotone)

| -1.1500 |
0.0701 |
0.295 |
0.177 |
-0.0523 |
0.643 |
| -1.0500 |
0.0882 |
0.295 |
0.180 |
-0.0581 |
0.649 |
| -0.9550 |
0.1110 |
0.295 |
0.180 |
-0.0581 |
0.649 |
| -0.8550 |
0.1400 |
0.295 |
0.180 |
-0.0581 |
0.649 |
| -0.7550 |
0.1760 |
0.295 |
0.180 |
-0.0581 |
0.649 |
| -0.6550 |
0.2220 |
0.295 |
0.185 |
-0.0669 |
0.658 |
| -0.5550 |
0.2790 |
0.295 |
0.185 |
-0.0669 |
0.658 |
| -0.4550 |
0.3510 |
0.295 |
0.187 |
-0.0711 |
0.662 |
| -0.3550 |
0.4420 |
0.295 |
0.186 |
-0.0688 |
0.660 |
| -0.2550 |
0.5560 |
0.295 |
0.186 |
-0.0688 |
0.660 |
| -0.1550 |
0.7010 |
0.295 |
0.188 |
-0.0730 |
0.664 |
| -0.0545 |
0.8820 |
0.295 |
0.190 |
-0.0767 |
0.667 |
| 0.0455 |
1.1100 |
0.295 |
0.191 |
-0.0781 |
0.669 |
| 0.1450 |
1.4000 |
0.295 |
0.184 |
-0.0652 |
0.656 |
| 0.2450 |
1.7600 |
0.295 |
0.186 |
-0.0696 |
0.660 |
| 0.3450 |
2.2200 |
0.295 |
0.191 |
-0.0794 |
0.670 |
| 0.4450 |
2.7900 |
0.295 |
0.192 |
-0.0803 |
0.671 |
| 0.5450 |
3.5100 |
0.295 |
0.200 |
-0.0967 |
0.687 |
| 0.6450 |
4.4200 |
0.295 |
0.214 |
-0.1230 |
0.714 |
| 0.7450 |
5.5600 |
0.295 |
0.240 |
-0.1760 |
0.766 |
| 0.8450 |
7.0100 |
0.295 |
0.266 |
-0.2260 |
0.817 |
| 0.9450 |
8.8200 |
0.295 |
0.269 |
-0.2320 |
0.823 |
| 1.0500 |
11.1000 |
0.295 |
0.279 |
-0.2510 |
0.842 |
| 1.1500 |
14.0000 |
0.295 |
0.315 |
-0.3210 |
0.912 |
| 1.2500 |
17.6000 |
0.295 |
0.308 |
-0.3090 |
0.900 |
| 1.3500 |
22.2000 |
0.295 |
0.314 |
-0.3190 |
0.910 |
| 1.4500 |
27.9000 |
0.295 |
0.331 |
-0.3540 |
0.945 |
| 1.5500 |
35.1000 |
0.295 |
0.282 |
-0.2570 |
0.848 |
| 1.6500 |
44.2000 |
0.295 |
0.312 |
-0.3170 |
0.907 |
| 1.7500 |
55.6000 |
0.295 |
0.376 |
-0.4420 |
1.030 |
| 1.8500 |
70.1000 |
0.295 |
0.476 |
-0.6380 |
1.230 |
| 1.9500 |
88.2000 |
0.295 |
0.727 |
-1.1300 |
1.720 |
| 2.0500 |
111.0000 |
0.295 |
0.736 |
-1.1500 |
1.740 |
| 2.1500 |
140.0000 |
0.295 |
0.906 |
-1.4800 |
2.070 |
| 2.2500 |
176.0000 |
0.295 |
1.030 |
-1.7300 |
2.320 |
IgG Spike Alpha
Vaccine
Unscaled (not monotone)

| 3.31 |
2040 |
0.00522 |
0.00105 |
0.003170 |
0.00727 |
| 3.41 |
2570 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.51 |
3230 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.61 |
4070 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.71 |
5120 |
0.00599 |
0.00136 |
0.003330 |
0.00865 |
| 3.81 |
6440 |
0.00599 |
0.00136 |
0.003330 |
0.00866 |
| 3.91 |
8110 |
0.00600 |
0.00136 |
0.003330 |
0.00866 |
| 4.01 |
10200 |
0.00600 |
0.00136 |
0.003330 |
0.00866 |
| 4.11 |
12900 |
0.00607 |
0.00138 |
0.003370 |
0.00878 |
| 4.21 |
16200 |
0.00609 |
0.00138 |
0.003390 |
0.00880 |
| 4.31 |
20400 |
0.00613 |
0.00139 |
0.003410 |
0.00886 |
| 4.41 |
25700 |
0.00621 |
0.00142 |
0.003420 |
0.00899 |
| 4.51 |
32300 |
0.00631 |
0.00143 |
0.003510 |
0.00911 |
| 4.61 |
40700 |
0.00634 |
0.00143 |
0.003530 |
0.00914 |
| 4.71 |
51200 |
0.00634 |
0.00143 |
0.003530 |
0.00916 |
| 4.81 |
64400 |
0.00661 |
0.00150 |
0.003670 |
0.00955 |
| 4.91 |
81100 |
0.00657 |
0.00153 |
0.003570 |
0.00957 |
| 5.01 |
102000 |
0.00688 |
0.00161 |
0.003720 |
0.01000 |
| 5.11 |
129000 |
0.00691 |
0.00168 |
0.003620 |
0.01020 |
| 5.21 |
162000 |
0.00661 |
0.00177 |
0.003130 |
0.01010 |
| 5.31 |
204000 |
0.00599 |
0.00175 |
0.002550 |
0.00943 |
| 5.41 |
257000 |
0.00475 |
0.00165 |
0.001530 |
0.00798 |
| 5.51 |
323000 |
0.00609 |
0.00235 |
0.001470 |
0.01070 |
| 5.61 |
407000 |
0.00262 |
0.00143 |
-0.000189 |
0.00543 |
Unscaled (monotone)

| 3.31 |
2040 |
0.0000 |
0.00619 |
0.00105 |
0.004140 |
0.00824 |
| 3.41 |
2570 |
0.0117 |
0.00619 |
0.00134 |
0.003570 |
0.00881 |
| 3.51 |
3230 |
0.0117 |
0.00619 |
0.00134 |
0.003570 |
0.00881 |
| 3.61 |
4070 |
0.0117 |
0.00619 |
0.00134 |
0.003570 |
0.00881 |
| 3.71 |
5120 |
0.0175 |
0.00619 |
0.00136 |
0.003530 |
0.00885 |
| 3.81 |
6440 |
0.0180 |
0.00619 |
0.00136 |
0.003530 |
0.00885 |
| 3.91 |
8110 |
0.0186 |
0.00619 |
0.00136 |
0.003520 |
0.00886 |
| 4.01 |
10200 |
0.0186 |
0.00619 |
0.00136 |
0.003520 |
0.00886 |
| 4.11 |
12900 |
0.0302 |
0.00619 |
0.00138 |
0.003480 |
0.00890 |
| 4.21 |
16200 |
0.0371 |
0.00619 |
0.00138 |
0.003480 |
0.00889 |
| 4.31 |
20400 |
0.0404 |
0.00619 |
0.00139 |
0.003460 |
0.00892 |
| 4.41 |
25700 |
0.0468 |
0.00619 |
0.00142 |
0.003400 |
0.00898 |
| 4.51 |
32300 |
0.0744 |
0.00619 |
0.00143 |
0.003390 |
0.00898 |
| 4.61 |
40700 |
0.0813 |
0.00619 |
0.00143 |
0.003380 |
0.00900 |
| 4.71 |
51200 |
0.0823 |
0.00619 |
0.00143 |
0.003380 |
0.00900 |
| 4.81 |
64400 |
0.1330 |
0.00619 |
0.00150 |
0.003250 |
0.00913 |
| 4.91 |
81100 |
0.1700 |
0.00619 |
0.00153 |
0.003190 |
0.00919 |
| 5.01 |
102000 |
0.1870 |
0.00619 |
0.00161 |
0.003020 |
0.00935 |
| 5.11 |
129000 |
0.2340 |
0.00619 |
0.00168 |
0.002900 |
0.00948 |
| 5.21 |
162000 |
0.3110 |
0.00619 |
0.00177 |
0.002710 |
0.00967 |
| 5.31 |
204000 |
0.3850 |
0.00599 |
0.00175 |
0.002550 |
0.00943 |
| 5.41 |
257000 |
0.5450 |
0.00537 |
0.00165 |
0.002150 |
0.00860 |
| 5.51 |
323000 |
0.6820 |
0.00537 |
0.00235 |
0.000760 |
0.00999 |
| 5.61 |
407000 |
0.7650 |
0.00262 |
0.00143 |
-0.000189 |
0.00543 |
VE scale (1 minus risk / placebo risk) (monotone)

| 3.31 |
2040 |
0.314 |
0.157 |
0.00583 |
0.622 |
| 3.41 |
2570 |
0.314 |
0.182 |
-0.04320 |
0.671 |
| 3.51 |
3230 |
0.314 |
0.182 |
-0.04320 |
0.671 |
| 3.61 |
4070 |
0.314 |
0.182 |
-0.04320 |
0.671 |
| 3.71 |
5120 |
0.314 |
0.184 |
-0.04690 |
0.674 |
| 3.81 |
6440 |
0.314 |
0.184 |
-0.04730 |
0.675 |
| 3.91 |
8110 |
0.314 |
0.184 |
-0.04760 |
0.675 |
| 4.01 |
10200 |
0.314 |
0.184 |
-0.04760 |
0.675 |
| 4.11 |
12900 |
0.314 |
0.186 |
-0.05130 |
0.679 |
| 4.21 |
16200 |
0.314 |
0.186 |
-0.05110 |
0.679 |
| 4.31 |
20400 |
0.314 |
0.187 |
-0.05320 |
0.681 |
| 4.41 |
25700 |
0.314 |
0.190 |
-0.05870 |
0.686 |
| 4.51 |
32300 |
0.314 |
0.190 |
-0.05950 |
0.687 |
| 4.61 |
40700 |
0.314 |
0.191 |
-0.06050 |
0.688 |
| 4.71 |
51200 |
0.314 |
0.191 |
-0.06090 |
0.688 |
| 4.81 |
64400 |
0.314 |
0.197 |
-0.07280 |
0.700 |
| 4.91 |
81100 |
0.314 |
0.200 |
-0.07830 |
0.706 |
| 5.01 |
102000 |
0.314 |
0.208 |
-0.09400 |
0.721 |
| 5.11 |
129000 |
0.314 |
0.214 |
-0.10600 |
0.734 |
| 5.21 |
162000 |
0.314 |
0.224 |
-0.12400 |
0.752 |
| 5.31 |
204000 |
0.335 |
0.220 |
-0.09560 |
0.767 |
| 5.41 |
257000 |
0.404 |
0.204 |
0.00359 |
0.805 |
| 5.51 |
323000 |
0.404 |
0.277 |
-0.13800 |
0.947 |
| 5.61 |
407000 |
0.710 |
0.165 |
0.38600 |
1.030 |
Placebo
Not monotone

| 2.4 |
252 |
0.00902 |
0.001390 |
0.006290 |
0.01170 |
| 2.5 |
317 |
0.00924 |
0.001930 |
0.005470 |
0.01300 |
| 2.6 |
399 |
0.00924 |
0.001930 |
0.005470 |
0.01300 |
| 2.7 |
503 |
0.00924 |
0.001930 |
0.005470 |
0.01300 |
| 2.8 |
633 |
0.00924 |
0.001930 |
0.005470 |
0.01300 |
| 2.9 |
796 |
0.00924 |
0.001930 |
0.005470 |
0.01300 |
| 3.0 |
1000 |
0.00930 |
0.001940 |
0.005500 |
0.01310 |
| 3.1 |
1260 |
0.00949 |
0.001980 |
0.005610 |
0.01340 |
| 3.2 |
1590 |
0.00920 |
0.001940 |
0.005400 |
0.01300 |
| 3.3 |
2000 |
0.00894 |
0.001910 |
0.005200 |
0.01270 |
| 3.4 |
2520 |
0.00842 |
0.001840 |
0.004810 |
0.01200 |
| 3.5 |
3170 |
0.00794 |
0.001790 |
0.004430 |
0.01150 |
| 3.6 |
3990 |
0.00789 |
0.001810 |
0.004330 |
0.01140 |
| 3.7 |
5030 |
0.00713 |
0.001710 |
0.003770 |
0.01050 |
| 3.8 |
6330 |
0.00683 |
0.001700 |
0.003500 |
0.01020 |
| 3.9 |
7960 |
0.00637 |
0.001650 |
0.003130 |
0.00961 |
| 4.0 |
10000 |
0.00622 |
0.001710 |
0.002860 |
0.00958 |
| 4.1 |
12600 |
0.00425 |
0.001430 |
0.001440 |
0.00706 |
| 4.2 |
15900 |
0.00424 |
0.001460 |
0.001370 |
0.00711 |
| 4.3 |
20000 |
0.00311 |
0.001250 |
0.000656 |
0.00557 |
| 4.4 |
25200 |
0.00257 |
0.001110 |
0.000396 |
0.00474 |
| 4.5 |
31700 |
0.00281 |
0.001240 |
0.000375 |
0.00524 |
| 4.6 |
39900 |
0.00244 |
0.001190 |
0.000113 |
0.00477 |
| 4.7 |
50300 |
0.00147 |
0.000944 |
-0.000377 |
0.00332 |
Monotone

| 2.4 |
252 |
0.0000 |
0.00925 |
0.001390 |
0.006520 |
0.01200 |
| 2.5 |
317 |
0.0151 |
0.00925 |
0.001930 |
0.005480 |
0.01300 |
| 2.6 |
399 |
0.0151 |
0.00925 |
0.001930 |
0.005480 |
0.01300 |
| 2.7 |
503 |
0.0151 |
0.00925 |
0.001930 |
0.005480 |
0.01300 |
| 2.8 |
633 |
0.0156 |
0.00925 |
0.001930 |
0.005470 |
0.01300 |
| 2.9 |
796 |
0.0156 |
0.00925 |
0.001930 |
0.005470 |
0.01300 |
| 3.0 |
1000 |
0.0206 |
0.00925 |
0.001940 |
0.005450 |
0.01310 |
| 3.1 |
1260 |
0.0488 |
0.00925 |
0.001980 |
0.005370 |
0.01310 |
| 3.2 |
1590 |
0.0491 |
0.00920 |
0.001940 |
0.005400 |
0.01300 |
| 3.3 |
2000 |
0.0524 |
0.00894 |
0.001910 |
0.005200 |
0.01270 |
| 3.4 |
2520 |
0.0604 |
0.00842 |
0.001840 |
0.004810 |
0.01200 |
| 3.5 |
3170 |
0.0854 |
0.00794 |
0.001790 |
0.004430 |
0.01150 |
| 3.6 |
3990 |
0.1170 |
0.00789 |
0.001810 |
0.004330 |
0.01140 |
| 3.7 |
5030 |
0.1460 |
0.00713 |
0.001710 |
0.003770 |
0.01050 |
| 3.8 |
6330 |
0.1870 |
0.00683 |
0.001700 |
0.003500 |
0.01020 |
| 3.9 |
7960 |
0.1980 |
0.00637 |
0.001650 |
0.003130 |
0.00961 |
| 4.0 |
10000 |
0.2730 |
0.00622 |
0.001710 |
0.002860 |
0.00958 |
| 4.1 |
12600 |
0.2980 |
0.00425 |
0.001430 |
0.001440 |
0.00706 |
| 4.2 |
15900 |
0.3970 |
0.00424 |
0.001460 |
0.001370 |
0.00711 |
| 4.3 |
20000 |
0.4410 |
0.00311 |
0.001250 |
0.000656 |
0.00557 |
| 4.4 |
25200 |
0.4630 |
0.00269 |
0.001110 |
0.000515 |
0.00486 |
| 4.5 |
31700 |
0.5350 |
0.00269 |
0.001240 |
0.000256 |
0.00512 |
| 4.6 |
39900 |
0.5530 |
0.00244 |
0.001190 |
0.000113 |
0.00477 |
| 4.7 |
50300 |
0.6200 |
0.00147 |
0.000944 |
-0.000377 |
0.00332 |
Vaccine (change)
Unscaled (not monotone)

| -1.1200 |
0.0757 |
0.00584 |
0.00131 |
3.28e-03 |
0.00841 |
| -1.0200 |
0.0953 |
0.00586 |
0.00131 |
3.29e-03 |
0.00843 |
| -0.9210 |
0.1200 |
0.00592 |
0.00133 |
3.31e-03 |
0.00852 |
| -0.8210 |
0.1510 |
0.00592 |
0.00133 |
3.31e-03 |
0.00852 |
| -0.7210 |
0.1900 |
0.00592 |
0.00133 |
3.31e-03 |
0.00852 |
| -0.6210 |
0.2390 |
0.00593 |
0.00134 |
3.31e-03 |
0.00855 |
| -0.5210 |
0.3010 |
0.00599 |
0.00136 |
3.32e-03 |
0.00866 |
| -0.4210 |
0.3790 |
0.00603 |
0.00138 |
3.33e-03 |
0.00874 |
| -0.3210 |
0.4780 |
0.00606 |
0.00137 |
3.38e-03 |
0.00875 |
| -0.2210 |
0.6010 |
0.00613 |
0.00139 |
3.42e-03 |
0.00885 |
| -0.1210 |
0.7570 |
0.00613 |
0.00139 |
3.42e-03 |
0.00885 |
| -0.0209 |
0.9530 |
0.00592 |
0.00136 |
3.25e-03 |
0.00858 |
| 0.0791 |
1.2000 |
0.00602 |
0.00138 |
3.30e-03 |
0.00873 |
| 0.1790 |
1.5100 |
0.00584 |
0.00138 |
3.15e-03 |
0.00854 |
| 0.2790 |
1.9000 |
0.00593 |
0.00140 |
3.19e-03 |
0.00867 |
| 0.3790 |
2.3900 |
0.00612 |
0.00147 |
3.25e-03 |
0.00900 |
| 0.4790 |
3.0100 |
0.00613 |
0.00152 |
3.15e-03 |
0.00910 |
| 0.5790 |
3.7900 |
0.00587 |
0.00148 |
2.97e-03 |
0.00876 |
| 0.6790 |
4.7800 |
0.00696 |
0.00185 |
3.34e-03 |
0.01060 |
| 0.7790 |
6.0100 |
0.00733 |
0.00197 |
3.46e-03 |
0.01120 |
| 0.8790 |
7.5700 |
0.00769 |
0.00210 |
3.57e-03 |
0.01180 |
| 0.9790 |
9.5300 |
0.00770 |
0.00210 |
3.58e-03 |
0.01180 |
| 1.0800 |
12.0000 |
0.00833 |
0.00234 |
3.75e-03 |
0.01290 |
| 1.1800 |
15.1000 |
0.00856 |
0.00252 |
3.61e-03 |
0.01350 |
| 1.2800 |
19.0000 |
0.00883 |
0.00264 |
3.65e-03 |
0.01400 |
| 1.3800 |
23.9000 |
0.00675 |
0.00253 |
1.80e-03 |
0.01170 |
| 1.4800 |
30.1000 |
0.00654 |
0.00244 |
1.74e-03 |
0.01130 |
| 1.5800 |
37.9000 |
0.00631 |
0.00252 |
1.36e-03 |
0.01130 |
| 1.6800 |
47.8000 |
0.00576 |
0.00294 |
-6.90e-06 |
0.01150 |
| 1.7800 |
60.1000 |
0.00534 |
0.00312 |
-7.68e-04 |
0.01150 |
| 1.8800 |
75.7000 |
0.00680 |
0.00403 |
-1.10e-03 |
0.01470 |
| 1.9800 |
95.3000 |
0.01200 |
0.00607 |
8.69e-05 |
0.02390 |
| 2.0800 |
120.0000 |
0.01880 |
0.01040 |
-1.59e-03 |
0.03910 |
Unscaled (monotone)

| -1.1200 |
0.0757 |
0.00000 |
0.00646 |
0.00131 |
0.003900 |
0.00902 |
| -1.0200 |
0.0953 |
0.00109 |
0.00646 |
0.00131 |
0.003890 |
0.00903 |
| -0.9210 |
0.1200 |
0.00692 |
0.00646 |
0.00133 |
0.003850 |
0.00907 |
| -0.8210 |
0.1510 |
0.00692 |
0.00646 |
0.00133 |
0.003850 |
0.00907 |
| -0.7210 |
0.1900 |
0.00692 |
0.00646 |
0.00133 |
0.003850 |
0.00907 |
| -0.6210 |
0.2390 |
0.00802 |
0.00646 |
0.00134 |
0.003840 |
0.00908 |
| -0.5210 |
0.3010 |
0.01380 |
0.00646 |
0.00136 |
0.003790 |
0.00913 |
| -0.4210 |
0.3790 |
0.01970 |
0.00646 |
0.00138 |
0.003760 |
0.00916 |
| -0.3210 |
0.4780 |
0.02920 |
0.00646 |
0.00137 |
0.003780 |
0.00914 |
| -0.2210 |
0.6010 |
0.04640 |
0.00646 |
0.00139 |
0.003740 |
0.00918 |
| -0.1210 |
0.7570 |
0.04690 |
0.00646 |
0.00139 |
0.003740 |
0.00918 |
| -0.0209 |
0.9530 |
0.06250 |
0.00646 |
0.00136 |
0.003800 |
0.00912 |
| 0.0791 |
1.2000 |
0.08720 |
0.00646 |
0.00138 |
0.003750 |
0.00917 |
| 0.1790 |
1.5100 |
0.10000 |
0.00646 |
0.00138 |
0.003760 |
0.00916 |
| 0.2790 |
1.9000 |
0.11900 |
0.00646 |
0.00140 |
0.003720 |
0.00920 |
| 0.3790 |
2.3900 |
0.14500 |
0.00646 |
0.00147 |
0.003590 |
0.00933 |
| 0.4790 |
3.0100 |
0.18000 |
0.00646 |
0.00152 |
0.003480 |
0.00944 |
| 0.5790 |
3.7900 |
0.19300 |
0.00646 |
0.00148 |
0.003560 |
0.00936 |
| 0.6790 |
4.7800 |
0.25400 |
0.00646 |
0.00185 |
0.002840 |
0.01010 |
| 0.7790 |
6.0100 |
0.30000 |
0.00646 |
0.00197 |
0.002600 |
0.01030 |
| 0.8790 |
7.5700 |
0.33900 |
0.00646 |
0.00210 |
0.002350 |
0.01060 |
| 0.9790 |
9.5300 |
0.34000 |
0.00646 |
0.00210 |
0.002340 |
0.01060 |
| 1.0800 |
12.0000 |
0.38200 |
0.00646 |
0.00234 |
0.001880 |
0.01100 |
| 1.1800 |
15.1000 |
0.44200 |
0.00646 |
0.00252 |
0.001510 |
0.01140 |
| 1.2800 |
19.0000 |
0.50300 |
0.00646 |
0.00264 |
0.001280 |
0.01160 |
| 1.3800 |
23.9000 |
0.58000 |
0.00646 |
0.00253 |
0.001510 |
0.01140 |
| 1.4800 |
30.1000 |
0.61400 |
0.00646 |
0.00244 |
0.001670 |
0.01130 |
| 1.5800 |
37.9000 |
0.63800 |
0.00646 |
0.00252 |
0.001510 |
0.01140 |
| 1.6800 |
47.8000 |
0.69100 |
0.00646 |
0.00294 |
0.000694 |
0.01220 |
| 1.7800 |
60.1000 |
0.76500 |
0.00646 |
0.00312 |
0.000349 |
0.01260 |
| 1.8800 |
75.7000 |
0.80100 |
0.00646 |
0.00403 |
-0.001440 |
0.01440 |
| 1.9800 |
95.3000 |
0.83200 |
0.00646 |
0.00607 |
-0.005440 |
0.01840 |
| 2.0800 |
120.0000 |
0.88400 |
0.00646 |
0.01040 |
-0.013900 |
0.02680 |
VE scale (1 minus risk / placebo risk) (monotone)

| -1.1200 |
0.0757 |
0.284 |
0.178 |
-0.0661 |
0.633 |
| -1.0200 |
0.0953 |
0.284 |
0.179 |
-0.0670 |
0.634 |
| -0.9210 |
0.1200 |
0.284 |
0.181 |
-0.0719 |
0.639 |
| -0.8210 |
0.1510 |
0.284 |
0.181 |
-0.0719 |
0.639 |
| -0.7210 |
0.1900 |
0.284 |
0.181 |
-0.0719 |
0.639 |
| -0.6210 |
0.2390 |
0.284 |
0.182 |
-0.0737 |
0.641 |
| -0.5210 |
0.3010 |
0.284 |
0.186 |
-0.0808 |
0.648 |
| -0.4210 |
0.3790 |
0.284 |
0.188 |
-0.0850 |
0.652 |
| -0.3210 |
0.4780 |
0.284 |
0.187 |
-0.0827 |
0.650 |
| -0.2210 |
0.6010 |
0.284 |
0.189 |
-0.0871 |
0.654 |
| -0.1210 |
0.7570 |
0.284 |
0.189 |
-0.0870 |
0.654 |
| -0.0209 |
0.9530 |
0.284 |
0.185 |
-0.0794 |
0.647 |
| 0.0791 |
1.2000 |
0.284 |
0.189 |
-0.0867 |
0.654 |
| 0.1790 |
1.5100 |
0.284 |
0.188 |
-0.0842 |
0.651 |
| 0.2790 |
1.9000 |
0.284 |
0.191 |
-0.0902 |
0.657 |
| 0.3790 |
2.3900 |
0.284 |
0.200 |
-0.1080 |
0.676 |
| 0.4790 |
3.0100 |
0.284 |
0.207 |
-0.1220 |
0.689 |
| 0.5790 |
3.7900 |
0.284 |
0.202 |
-0.1120 |
0.679 |
| 0.6790 |
4.7800 |
0.284 |
0.252 |
-0.2100 |
0.778 |
| 0.7790 |
6.0100 |
0.284 |
0.269 |
-0.2440 |
0.811 |
| 0.8790 |
7.5700 |
0.284 |
0.286 |
-0.2780 |
0.845 |
| 0.9790 |
9.5300 |
0.284 |
0.287 |
-0.2790 |
0.846 |
| 1.0800 |
12.0000 |
0.284 |
0.319 |
-0.3420 |
0.909 |
| 1.1800 |
15.1000 |
0.284 |
0.344 |
-0.3910 |
0.959 |
| 1.2800 |
19.0000 |
0.284 |
0.361 |
-0.4230 |
0.990 |
| 1.3800 |
23.9000 |
0.284 |
0.345 |
-0.3920 |
0.959 |
| 1.4800 |
30.1000 |
0.284 |
0.334 |
-0.3700 |
0.937 |
| 1.5800 |
37.9000 |
0.284 |
0.344 |
-0.3910 |
0.959 |
| 1.6800 |
47.8000 |
0.284 |
0.401 |
-0.5030 |
1.070 |
| 1.7800 |
60.1000 |
0.284 |
0.425 |
-0.5500 |
1.120 |
| 1.8800 |
75.7000 |
0.284 |
0.550 |
-0.7940 |
1.360 |
| 1.9800 |
95.3000 |
0.284 |
0.828 |
-1.3400 |
1.910 |
| 2.0800 |
120.0000 |
0.284 |
1.420 |
-2.4900 |
3.060 |
IgG Spike Gamma
Vaccine
Unscaled (not monotone)

| 3.18 |
1500 |
0.00522 |
0.00105 |
0.003170 |
0.00727 |
| 3.28 |
1890 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.38 |
2380 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.48 |
3000 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.58 |
3780 |
0.00599 |
0.00136 |
0.003330 |
0.00865 |
| 3.68 |
4750 |
0.00599 |
0.00136 |
0.003330 |
0.00866 |
| 3.78 |
5980 |
0.00600 |
0.00136 |
0.003330 |
0.00866 |
| 3.88 |
7530 |
0.00606 |
0.00139 |
0.003340 |
0.00878 |
| 3.98 |
9480 |
0.00608 |
0.00138 |
0.003370 |
0.00878 |
| 4.08 |
11900 |
0.00611 |
0.00139 |
0.003390 |
0.00883 |
| 4.18 |
15000 |
0.00611 |
0.00139 |
0.003390 |
0.00883 |
| 4.28 |
18900 |
0.00619 |
0.00142 |
0.003410 |
0.00898 |
| 4.38 |
23800 |
0.00630 |
0.00145 |
0.003460 |
0.00914 |
| 4.48 |
30000 |
0.00631 |
0.00143 |
0.003510 |
0.00911 |
| 4.58 |
37800 |
0.00633 |
0.00143 |
0.003530 |
0.00913 |
| 4.68 |
47500 |
0.00634 |
0.00143 |
0.003530 |
0.00916 |
| 4.78 |
59800 |
0.00680 |
0.00156 |
0.003740 |
0.00986 |
| 4.88 |
75300 |
0.00677 |
0.00158 |
0.003670 |
0.00987 |
| 4.98 |
94800 |
0.00700 |
0.00165 |
0.003770 |
0.01020 |
| 5.08 |
119000 |
0.00726 |
0.00182 |
0.003690 |
0.01080 |
| 5.18 |
150000 |
0.00626 |
0.00172 |
0.002900 |
0.00963 |
| 5.28 |
189000 |
0.00542 |
0.00173 |
0.002030 |
0.00881 |
| 5.38 |
238000 |
0.00485 |
0.00180 |
0.001310 |
0.00838 |
| 5.48 |
300000 |
0.00569 |
0.00234 |
0.001100 |
0.01030 |
| 5.58 |
378000 |
0.00265 |
0.00141 |
-0.000118 |
0.00543 |
Unscaled (monotone)

| 3.18 |
1500 |
0.0000 |
0.00622 |
0.00105 |
0.004170 |
0.00827 |
| 3.28 |
1890 |
0.0117 |
0.00622 |
0.00134 |
0.003600 |
0.00884 |
| 3.38 |
2380 |
0.0117 |
0.00622 |
0.00134 |
0.003600 |
0.00884 |
| 3.48 |
3000 |
0.0117 |
0.00622 |
0.00134 |
0.003600 |
0.00884 |
| 3.58 |
3780 |
0.0175 |
0.00622 |
0.00136 |
0.003560 |
0.00888 |
| 3.68 |
4750 |
0.0180 |
0.00622 |
0.00136 |
0.003560 |
0.00888 |
| 3.78 |
5980 |
0.0186 |
0.00622 |
0.00136 |
0.003550 |
0.00889 |
| 3.88 |
7530 |
0.0249 |
0.00622 |
0.00139 |
0.003500 |
0.00894 |
| 3.98 |
9480 |
0.0313 |
0.00622 |
0.00138 |
0.003510 |
0.00893 |
| 4.08 |
11900 |
0.0382 |
0.00622 |
0.00139 |
0.003500 |
0.00894 |
| 4.18 |
15000 |
0.0382 |
0.00622 |
0.00139 |
0.003500 |
0.00894 |
| 4.28 |
18900 |
0.0457 |
0.00622 |
0.00142 |
0.003440 |
0.00900 |
| 4.38 |
23800 |
0.0643 |
0.00622 |
0.00145 |
0.003380 |
0.00906 |
| 4.48 |
30000 |
0.0744 |
0.00622 |
0.00143 |
0.003420 |
0.00902 |
| 4.58 |
37800 |
0.0807 |
0.00622 |
0.00143 |
0.003420 |
0.00902 |
| 4.68 |
47500 |
0.0818 |
0.00622 |
0.00143 |
0.003410 |
0.00903 |
| 4.78 |
59800 |
0.1260 |
0.00622 |
0.00156 |
0.003160 |
0.00928 |
| 4.88 |
75300 |
0.1710 |
0.00622 |
0.00158 |
0.003120 |
0.00932 |
| 4.98 |
94800 |
0.2020 |
0.00622 |
0.00165 |
0.002980 |
0.00946 |
| 5.08 |
119000 |
0.2580 |
0.00622 |
0.00182 |
0.002650 |
0.00979 |
| 5.18 |
150000 |
0.3050 |
0.00622 |
0.00172 |
0.002850 |
0.00958 |
| 5.28 |
189000 |
0.4690 |
0.00542 |
0.00173 |
0.002030 |
0.00881 |
| 5.38 |
238000 |
0.5950 |
0.00485 |
0.00180 |
0.001310 |
0.00838 |
| 5.48 |
300000 |
0.6900 |
0.00485 |
0.00234 |
0.000256 |
0.00944 |
| 5.58 |
378000 |
0.7810 |
0.00265 |
0.00141 |
-0.000118 |
0.00543 |
VE scale (1 minus risk / placebo risk) (monotone)

| 3.18 |
1500 |
0.310 |
0.157 |
0.0017 |
0.619 |
| 3.28 |
1890 |
0.310 |
0.182 |
-0.0472 |
0.668 |
| 3.38 |
2380 |
0.310 |
0.182 |
-0.0472 |
0.668 |
| 3.48 |
3000 |
0.310 |
0.182 |
-0.0472 |
0.668 |
| 3.58 |
3780 |
0.310 |
0.184 |
-0.0509 |
0.672 |
| 3.68 |
4750 |
0.310 |
0.185 |
-0.0513 |
0.672 |
| 3.78 |
5980 |
0.310 |
0.185 |
-0.0517 |
0.672 |
| 3.88 |
7530 |
0.310 |
0.187 |
-0.0564 |
0.677 |
| 3.98 |
9480 |
0.310 |
0.187 |
-0.0553 |
0.676 |
| 4.08 |
11900 |
0.310 |
0.187 |
-0.0563 |
0.677 |
| 4.18 |
15000 |
0.310 |
0.187 |
-0.0563 |
0.677 |
| 4.28 |
18900 |
0.310 |
0.190 |
-0.0623 |
0.683 |
| 4.38 |
23800 |
0.310 |
0.193 |
-0.0673 |
0.688 |
| 4.48 |
30000 |
0.310 |
0.191 |
-0.0635 |
0.684 |
| 4.58 |
37800 |
0.310 |
0.191 |
-0.0642 |
0.685 |
| 4.68 |
47500 |
0.310 |
0.191 |
-0.0649 |
0.686 |
| 4.78 |
59800 |
0.310 |
0.203 |
-0.0882 |
0.709 |
| 4.88 |
75300 |
0.310 |
0.205 |
-0.0917 |
0.712 |
| 4.98 |
94800 |
0.310 |
0.212 |
-0.1050 |
0.725 |
| 5.08 |
119000 |
0.310 |
0.228 |
-0.1370 |
0.758 |
| 5.18 |
150000 |
0.310 |
0.218 |
-0.1170 |
0.738 |
| 5.28 |
189000 |
0.399 |
0.213 |
-0.0191 |
0.816 |
| 5.38 |
238000 |
0.463 |
0.216 |
0.0384 |
0.887 |
| 5.48 |
300000 |
0.463 |
0.273 |
-0.0719 |
0.997 |
| 5.58 |
378000 |
0.706 |
0.163 |
0.3850 |
1.030 |
Placebo
Not monotone

| 2.4 |
252 |
0.00902 |
0.00139 |
0.006290 |
0.01170 |
| 2.5 |
317 |
0.00920 |
0.00192 |
0.005440 |
0.01300 |
| 2.6 |
399 |
0.00920 |
0.00192 |
0.005440 |
0.01300 |
| 2.7 |
503 |
0.00920 |
0.00192 |
0.005440 |
0.01300 |
| 2.8 |
633 |
0.00932 |
0.00194 |
0.005510 |
0.01310 |
| 2.9 |
796 |
0.00921 |
0.00194 |
0.005400 |
0.01300 |
| 3.0 |
1000 |
0.00923 |
0.00195 |
0.005410 |
0.01300 |
| 3.1 |
1260 |
0.00895 |
0.00191 |
0.005200 |
0.01270 |
| 3.2 |
1590 |
0.00861 |
0.00189 |
0.004900 |
0.01230 |
| 3.3 |
2000 |
0.00832 |
0.00185 |
0.004690 |
0.01200 |
| 3.4 |
2520 |
0.00846 |
0.00189 |
0.004750 |
0.01220 |
| 3.5 |
3170 |
0.00795 |
0.00182 |
0.004380 |
0.01150 |
| 3.6 |
3990 |
0.00652 |
0.00162 |
0.003340 |
0.00971 |
| 3.7 |
5030 |
0.00649 |
0.00169 |
0.003190 |
0.00979 |
| 3.8 |
6330 |
0.00632 |
0.00169 |
0.003010 |
0.00963 |
| 3.9 |
7960 |
0.00565 |
0.00159 |
0.002530 |
0.00876 |
| 4.0 |
10000 |
0.00420 |
0.00141 |
0.001440 |
0.00695 |
| 4.1 |
12600 |
0.00427 |
0.00147 |
0.001390 |
0.00715 |
| 4.2 |
15900 |
0.00357 |
0.00137 |
0.000888 |
0.00624 |
| 4.3 |
20000 |
0.00332 |
0.00137 |
0.000628 |
0.00601 |
| 4.4 |
25200 |
0.00285 |
0.00130 |
0.000307 |
0.00539 |
| 4.5 |
31700 |
0.00189 |
0.00104 |
-0.000143 |
0.00392 |
| 4.6 |
39900 |
0.00194 |
0.00105 |
-0.000124 |
0.00401 |
Monotone

| 2.4 |
252 |
0.0000 |
0.00919 |
0.00139 |
0.006470 |
0.01190 |
| 2.5 |
317 |
0.0043 |
0.00919 |
0.00192 |
0.005430 |
0.01300 |
| 2.6 |
399 |
0.0043 |
0.00919 |
0.00192 |
0.005430 |
0.01300 |
| 2.7 |
503 |
0.0043 |
0.00919 |
0.00192 |
0.005430 |
0.01300 |
| 2.8 |
633 |
0.0211 |
0.00919 |
0.00194 |
0.005390 |
0.01300 |
| 2.9 |
796 |
0.0496 |
0.00919 |
0.00194 |
0.005380 |
0.01300 |
| 3.0 |
1000 |
0.0511 |
0.00919 |
0.00195 |
0.005370 |
0.01300 |
| 3.1 |
1260 |
0.0548 |
0.00895 |
0.00191 |
0.005200 |
0.01270 |
| 3.2 |
1590 |
0.0861 |
0.00861 |
0.00189 |
0.004900 |
0.01230 |
| 3.3 |
2000 |
0.0899 |
0.00839 |
0.00185 |
0.004760 |
0.01200 |
| 3.4 |
2520 |
0.1150 |
0.00839 |
0.00189 |
0.004690 |
0.01210 |
| 3.5 |
3170 |
0.1390 |
0.00795 |
0.00182 |
0.004380 |
0.01150 |
| 3.6 |
3990 |
0.1550 |
0.00652 |
0.00162 |
0.003340 |
0.00971 |
| 3.7 |
5030 |
0.2160 |
0.00649 |
0.00169 |
0.003190 |
0.00979 |
| 3.8 |
6330 |
0.2580 |
0.00632 |
0.00169 |
0.003010 |
0.00963 |
| 3.9 |
7960 |
0.2680 |
0.00565 |
0.00159 |
0.002530 |
0.00876 |
| 4.0 |
10000 |
0.3420 |
0.00423 |
0.00141 |
0.001480 |
0.00699 |
| 4.1 |
12600 |
0.4220 |
0.00423 |
0.00147 |
0.001350 |
0.00711 |
| 4.2 |
15900 |
0.4570 |
0.00357 |
0.00137 |
0.000888 |
0.00624 |
| 4.3 |
20000 |
0.4860 |
0.00332 |
0.00137 |
0.000628 |
0.00601 |
| 4.4 |
25200 |
0.5130 |
0.00285 |
0.00130 |
0.000307 |
0.00539 |
| 4.5 |
31700 |
0.5700 |
0.00192 |
0.00104 |
-0.000117 |
0.00395 |
| 4.6 |
39900 |
0.5960 |
0.00192 |
0.00105 |
-0.000150 |
0.00398 |
Vaccine (change)
Unscaled (not monotone)

| -1.0500 |
0.0884 |
0.00584 |
0.00131 |
0.003280 |
0.00841 |
| -0.9540 |
0.1110 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.8540 |
0.1400 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.7540 |
0.1760 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.6540 |
0.2220 |
0.00593 |
0.00134 |
0.003310 |
0.00855 |
| -0.5540 |
0.2800 |
0.00603 |
0.00138 |
0.003330 |
0.00874 |
| -0.4540 |
0.3520 |
0.00604 |
0.00138 |
0.003340 |
0.00874 |
| -0.3540 |
0.4430 |
0.00604 |
0.00138 |
0.003340 |
0.00874 |
| -0.2540 |
0.5580 |
0.00608 |
0.00137 |
0.003390 |
0.00876 |
| -0.1540 |
0.7020 |
0.00613 |
0.00139 |
0.003420 |
0.00885 |
| -0.0535 |
0.8840 |
0.00620 |
0.00140 |
0.003450 |
0.00894 |
| 0.0465 |
1.1100 |
0.00597 |
0.00138 |
0.003270 |
0.00867 |
| 0.1460 |
1.4000 |
0.00600 |
0.00138 |
0.003290 |
0.00870 |
| 0.2460 |
1.7600 |
0.00584 |
0.00138 |
0.003140 |
0.00853 |
| 0.3460 |
2.2200 |
0.00600 |
0.00143 |
0.003200 |
0.00879 |
| 0.4460 |
2.8000 |
0.00601 |
0.00143 |
0.003210 |
0.00881 |
| 0.5460 |
3.5200 |
0.00627 |
0.00151 |
0.003320 |
0.00922 |
| 0.6460 |
4.4300 |
0.00593 |
0.00150 |
0.002980 |
0.00887 |
| 0.7460 |
5.5800 |
0.00719 |
0.00196 |
0.003350 |
0.01100 |
| 0.8460 |
7.0200 |
0.00753 |
0.00209 |
0.003440 |
0.01160 |
| 0.9460 |
8.8400 |
0.00782 |
0.00217 |
0.003560 |
0.01210 |
| 1.0500 |
11.1000 |
0.00782 |
0.00217 |
0.003570 |
0.01210 |
| 1.1500 |
14.0000 |
0.00823 |
0.00227 |
0.003780 |
0.01270 |
| 1.2500 |
17.6000 |
0.00716 |
0.00205 |
0.003140 |
0.01120 |
| 1.3500 |
22.2000 |
0.00748 |
0.00228 |
0.003010 |
0.01200 |
| 1.4500 |
28.0000 |
0.00714 |
0.00232 |
0.002590 |
0.01170 |
| 1.5500 |
35.2000 |
0.00650 |
0.00233 |
0.001940 |
0.01110 |
| 1.6500 |
44.3000 |
0.00618 |
0.00247 |
0.001330 |
0.01100 |
| 1.7500 |
55.8000 |
0.00558 |
0.00276 |
0.000165 |
0.01100 |
| 1.8500 |
70.2000 |
0.00547 |
0.00301 |
-0.000422 |
0.01140 |
| 1.9500 |
88.4000 |
0.00500 |
0.00344 |
-0.001730 |
0.01170 |
| 2.0500 |
111.0000 |
0.00697 |
0.00354 |
0.000031 |
0.01390 |
| 2.1500 |
140.0000 |
0.00796 |
0.00416 |
-0.000193 |
0.01610 |
Unscaled (monotone)

| -1.0500 |
0.0884 |
0.00000 |
0.00642 |
0.00131 |
0.003860 |
0.00899 |
| -0.9540 |
0.1110 |
0.00692 |
0.00642 |
0.00133 |
0.003820 |
0.00903 |
| -0.8540 |
0.1400 |
0.00692 |
0.00642 |
0.00133 |
0.003820 |
0.00903 |
| -0.7540 |
0.1760 |
0.00692 |
0.00642 |
0.00133 |
0.003820 |
0.00903 |
| -0.6540 |
0.2220 |
0.00802 |
0.00642 |
0.00134 |
0.003810 |
0.00904 |
| -0.5540 |
0.2800 |
0.01970 |
0.00642 |
0.00138 |
0.003720 |
0.00913 |
| -0.4540 |
0.3520 |
0.02020 |
0.00642 |
0.00138 |
0.003720 |
0.00913 |
| -0.3540 |
0.4430 |
0.02020 |
0.00642 |
0.00138 |
0.003720 |
0.00913 |
| -0.2540 |
0.5580 |
0.03560 |
0.00642 |
0.00137 |
0.003740 |
0.00911 |
| -0.1540 |
0.7020 |
0.04640 |
0.00642 |
0.00139 |
0.003710 |
0.00914 |
| -0.0535 |
0.8840 |
0.06810 |
0.00642 |
0.00140 |
0.003680 |
0.00917 |
| 0.0465 |
1.1100 |
0.07470 |
0.00642 |
0.00138 |
0.003720 |
0.00913 |
| 0.1460 |
1.4000 |
0.08130 |
0.00642 |
0.00138 |
0.003720 |
0.00913 |
| 0.2460 |
1.7600 |
0.09980 |
0.00642 |
0.00138 |
0.003730 |
0.00912 |
| 0.3460 |
2.2200 |
0.12500 |
0.00642 |
0.00143 |
0.003630 |
0.00922 |
| 0.4460 |
2.8000 |
0.12700 |
0.00642 |
0.00143 |
0.003620 |
0.00922 |
| 0.5460 |
3.5200 |
0.16800 |
0.00642 |
0.00151 |
0.003470 |
0.00938 |
| 0.6460 |
4.4300 |
0.19800 |
0.00642 |
0.00150 |
0.003480 |
0.00937 |
| 0.7460 |
5.5800 |
0.27400 |
0.00642 |
0.00196 |
0.002590 |
0.01030 |
| 0.8460 |
7.0200 |
0.31200 |
0.00642 |
0.00209 |
0.002330 |
0.01050 |
| 0.9460 |
8.8400 |
0.34500 |
0.00642 |
0.00217 |
0.002170 |
0.01070 |
| 1.0500 |
11.1000 |
0.34700 |
0.00642 |
0.00217 |
0.002180 |
0.01070 |
| 1.1500 |
14.0000 |
0.37300 |
0.00642 |
0.00227 |
0.001970 |
0.01090 |
| 1.2500 |
17.6000 |
0.42900 |
0.00642 |
0.00205 |
0.002400 |
0.01040 |
| 1.3500 |
22.2000 |
0.47700 |
0.00642 |
0.00228 |
0.001950 |
0.01090 |
| 1.4500 |
28.0000 |
0.54500 |
0.00642 |
0.00232 |
0.001880 |
0.01100 |
| 1.5500 |
35.2000 |
0.58500 |
0.00642 |
0.00233 |
0.001860 |
0.01100 |
| 1.6500 |
44.3000 |
0.64200 |
0.00619 |
0.00247 |
0.001340 |
0.01100 |
| 1.7500 |
55.8000 |
0.67500 |
0.00619 |
0.00276 |
0.000775 |
0.01160 |
| 1.8500 |
70.2000 |
0.73200 |
0.00619 |
0.00301 |
0.000302 |
0.01210 |
| 1.9500 |
88.4000 |
0.78000 |
0.00619 |
0.00344 |
-0.000543 |
0.01290 |
| 2.0500 |
111.0000 |
0.82000 |
0.00619 |
0.00354 |
-0.000743 |
0.01310 |
| 2.1500 |
140.0000 |
0.84100 |
0.00619 |
0.00416 |
-0.001960 |
0.01430 |
VE scale (1 minus risk / placebo risk) (monotone)

| -1.0500 |
0.0884 |
0.288 |
0.178 |
-0.0614 |
0.637 |
| -0.9540 |
0.1110 |
0.288 |
0.181 |
-0.0672 |
0.642 |
| -0.8540 |
0.1400 |
0.288 |
0.181 |
-0.0672 |
0.642 |
| -0.7540 |
0.1760 |
0.288 |
0.181 |
-0.0672 |
0.642 |
| -0.6540 |
0.2220 |
0.288 |
0.182 |
-0.0690 |
0.644 |
| -0.5540 |
0.2800 |
0.288 |
0.188 |
-0.0802 |
0.655 |
| -0.4540 |
0.3520 |
0.288 |
0.188 |
-0.0804 |
0.656 |
| -0.3540 |
0.4430 |
0.288 |
0.188 |
-0.0804 |
0.656 |
| -0.2540 |
0.5580 |
0.288 |
0.186 |
-0.0779 |
0.653 |
| -0.1540 |
0.7020 |
0.288 |
0.189 |
-0.0822 |
0.657 |
| -0.0535 |
0.8840 |
0.288 |
0.191 |
-0.0864 |
0.661 |
| 0.0465 |
1.1100 |
0.288 |
0.188 |
-0.0802 |
0.655 |
| 0.1460 |
1.4000 |
0.288 |
0.188 |
-0.0813 |
0.656 |
| 0.2460 |
1.7600 |
0.288 |
0.187 |
-0.0799 |
0.655 |
| 0.3460 |
2.2200 |
0.288 |
0.194 |
-0.0928 |
0.668 |
| 0.4460 |
2.8000 |
0.288 |
0.195 |
-0.0937 |
0.669 |
| 0.5460 |
3.5200 |
0.288 |
0.205 |
-0.1150 |
0.690 |
| 0.6460 |
4.4300 |
0.288 |
0.205 |
-0.1140 |
0.689 |
| 0.7460 |
5.5800 |
0.288 |
0.267 |
-0.2350 |
0.810 |
| 0.8460 |
7.0200 |
0.288 |
0.284 |
-0.2690 |
0.845 |
| 0.9460 |
8.8400 |
0.288 |
0.295 |
-0.2910 |
0.866 |
| 1.0500 |
11.1000 |
0.288 |
0.295 |
-0.2900 |
0.866 |
| 1.1500 |
14.0000 |
0.288 |
0.309 |
-0.3180 |
0.893 |
| 1.2500 |
17.6000 |
0.288 |
0.279 |
-0.2600 |
0.835 |
| 1.3500 |
22.2000 |
0.288 |
0.311 |
-0.3210 |
0.896 |
| 1.4500 |
28.0000 |
0.288 |
0.316 |
-0.3310 |
0.906 |
| 1.5500 |
35.2000 |
0.288 |
0.317 |
-0.3340 |
0.910 |
| 1.6500 |
44.3000 |
0.313 |
0.333 |
-0.3390 |
0.966 |
| 1.7500 |
55.8000 |
0.313 |
0.372 |
-0.4160 |
1.040 |
| 1.8500 |
70.2000 |
0.313 |
0.404 |
-0.4790 |
1.110 |
| 1.9500 |
88.4000 |
0.313 |
0.462 |
-0.5930 |
1.220 |
| 2.0500 |
111.0000 |
0.313 |
0.476 |
-0.6200 |
1.250 |
| 2.1500 |
140.0000 |
0.313 |
0.559 |
-0.7830 |
1.410 |
IgG Spike Delta1
Vaccine
Unscaled (not monotone)

| 3.14 |
1370 |
0.00522 |
0.00105 |
0.003170 |
0.00727 |
| 3.24 |
1730 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.34 |
2180 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.44 |
2740 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.54 |
3450 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.64 |
4350 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.74 |
5470 |
0.00599 |
0.00136 |
0.003330 |
0.00865 |
| 3.84 |
6890 |
0.00599 |
0.00136 |
0.003330 |
0.00865 |
| 3.94 |
8670 |
0.00599 |
0.00136 |
0.003330 |
0.00866 |
| 4.04 |
10900 |
0.00601 |
0.00136 |
0.003350 |
0.00867 |
| 4.14 |
13700 |
0.00608 |
0.00138 |
0.003370 |
0.00878 |
| 4.24 |
17300 |
0.00610 |
0.00139 |
0.003380 |
0.00882 |
| 4.34 |
21800 |
0.00621 |
0.00142 |
0.003420 |
0.00900 |
| 4.44 |
27400 |
0.00625 |
0.00141 |
0.003490 |
0.00901 |
| 4.54 |
34500 |
0.00625 |
0.00141 |
0.003500 |
0.00901 |
| 4.64 |
43500 |
0.00641 |
0.00146 |
0.003550 |
0.00926 |
| 4.74 |
54700 |
0.00646 |
0.00146 |
0.003590 |
0.00932 |
| 4.84 |
68900 |
0.00661 |
0.00150 |
0.003670 |
0.00954 |
| 4.94 |
86700 |
0.00650 |
0.00151 |
0.003550 |
0.00946 |
| 5.04 |
109000 |
0.00668 |
0.00160 |
0.003540 |
0.00982 |
| 5.14 |
137000 |
0.00689 |
0.00173 |
0.003510 |
0.01030 |
| 5.24 |
173000 |
0.00628 |
0.00172 |
0.002900 |
0.00966 |
| 5.34 |
218000 |
0.00637 |
0.00188 |
0.002700 |
0.01010 |
| 5.44 |
274000 |
0.00524 |
0.00181 |
0.001700 |
0.00879 |
| 5.54 |
345000 |
0.00510 |
0.00227 |
0.000662 |
0.00954 |
| 5.64 |
435000 |
0.00240 |
0.00128 |
-0.000118 |
0.00491 |
Unscaled (monotone)

| 3.14 |
1370 |
0.0000 |
0.00616 |
0.00105 |
0.004110 |
0.00821 |
| 3.24 |
1730 |
0.0117 |
0.00616 |
0.00134 |
0.003540 |
0.00878 |
| 3.34 |
2180 |
0.0117 |
0.00616 |
0.00134 |
0.003540 |
0.00878 |
| 3.44 |
2740 |
0.0117 |
0.00616 |
0.00134 |
0.003540 |
0.00878 |
| 3.54 |
3450 |
0.0117 |
0.00616 |
0.00134 |
0.003540 |
0.00878 |
| 3.64 |
4350 |
0.0117 |
0.00616 |
0.00134 |
0.003540 |
0.00878 |
| 3.74 |
5470 |
0.0175 |
0.00616 |
0.00136 |
0.003500 |
0.00882 |
| 3.84 |
6890 |
0.0175 |
0.00616 |
0.00136 |
0.003500 |
0.00882 |
| 3.94 |
8670 |
0.0180 |
0.00616 |
0.00136 |
0.003500 |
0.00882 |
| 4.04 |
10900 |
0.0244 |
0.00616 |
0.00136 |
0.003500 |
0.00882 |
| 4.14 |
13700 |
0.0308 |
0.00616 |
0.00138 |
0.003450 |
0.00887 |
| 4.24 |
17300 |
0.0324 |
0.00616 |
0.00139 |
0.003440 |
0.00888 |
| 4.34 |
21800 |
0.0462 |
0.00616 |
0.00142 |
0.003370 |
0.00895 |
| 4.44 |
27400 |
0.0680 |
0.00616 |
0.00141 |
0.003400 |
0.00892 |
| 4.54 |
34500 |
0.0691 |
0.00616 |
0.00141 |
0.003400 |
0.00892 |
| 4.64 |
43500 |
0.0915 |
0.00616 |
0.00146 |
0.003310 |
0.00901 |
| 4.74 |
54700 |
0.1060 |
0.00616 |
0.00146 |
0.003290 |
0.00903 |
| 4.84 |
68900 |
0.1330 |
0.00616 |
0.00150 |
0.003220 |
0.00910 |
| 4.94 |
86700 |
0.1630 |
0.00616 |
0.00151 |
0.003200 |
0.00911 |
| 5.04 |
109000 |
0.2070 |
0.00616 |
0.00160 |
0.003020 |
0.00930 |
| 5.14 |
137000 |
0.2720 |
0.00616 |
0.00173 |
0.002780 |
0.00954 |
| 5.24 |
173000 |
0.3160 |
0.00616 |
0.00172 |
0.002780 |
0.00953 |
| 5.34 |
218000 |
0.4380 |
0.00616 |
0.00188 |
0.002480 |
0.00984 |
| 5.44 |
274000 |
0.5480 |
0.00524 |
0.00181 |
0.001700 |
0.00879 |
| 5.54 |
345000 |
0.6750 |
0.00510 |
0.00227 |
0.000662 |
0.00954 |
| 5.64 |
435000 |
0.7490 |
0.00240 |
0.00128 |
-0.000118 |
0.00491 |
VE scale (1 minus risk / placebo risk) (monotone)

| 3.14 |
1370 |
0.317 |
0.157 |
0.00986 |
0.624 |
| 3.24 |
1730 |
0.317 |
0.182 |
-0.03920 |
0.673 |
| 3.34 |
2180 |
0.317 |
0.182 |
-0.03920 |
0.673 |
| 3.44 |
2740 |
0.317 |
0.182 |
-0.03920 |
0.673 |
| 3.54 |
3450 |
0.317 |
0.182 |
-0.03920 |
0.673 |
| 3.64 |
4350 |
0.317 |
0.182 |
-0.03920 |
0.673 |
| 3.74 |
5470 |
0.317 |
0.184 |
-0.04300 |
0.677 |
| 3.84 |
6890 |
0.317 |
0.184 |
-0.04300 |
0.677 |
| 3.94 |
8670 |
0.317 |
0.184 |
-0.04340 |
0.678 |
| 4.04 |
10900 |
0.317 |
0.184 |
-0.04290 |
0.677 |
| 4.14 |
13700 |
0.317 |
0.186 |
-0.04750 |
0.682 |
| 4.24 |
17300 |
0.317 |
0.187 |
-0.04880 |
0.683 |
| 4.34 |
21800 |
0.317 |
0.190 |
-0.05510 |
0.689 |
| 4.44 |
27400 |
0.317 |
0.188 |
-0.05210 |
0.686 |
| 4.54 |
34500 |
0.317 |
0.188 |
-0.05220 |
0.686 |
| 4.64 |
43500 |
0.317 |
0.193 |
-0.06080 |
0.695 |
| 4.74 |
54700 |
0.317 |
0.193 |
-0.06210 |
0.696 |
| 4.84 |
68900 |
0.317 |
0.197 |
-0.06880 |
0.703 |
| 4.94 |
86700 |
0.317 |
0.198 |
-0.07020 |
0.704 |
| 5.04 |
109000 |
0.317 |
0.207 |
-0.08780 |
0.722 |
| 5.14 |
137000 |
0.317 |
0.218 |
-0.11100 |
0.745 |
| 5.24 |
173000 |
0.317 |
0.218 |
-0.11100 |
0.745 |
| 5.34 |
218000 |
0.317 |
0.233 |
-0.14000 |
0.774 |
| 5.44 |
274000 |
0.419 |
0.220 |
-0.01190 |
0.849 |
| 5.54 |
345000 |
0.434 |
0.266 |
-0.08720 |
0.956 |
| 5.64 |
435000 |
0.734 |
0.148 |
0.44400 |
1.020 |
Placebo
Not monotone

| 2.4 |
252 |
0.00902 |
0.00139 |
0.006290 |
0.01170 |
| 2.5 |
317 |
0.00918 |
0.00192 |
0.005430 |
0.01290 |
| 2.6 |
399 |
0.00918 |
0.00192 |
0.005430 |
0.01290 |
| 2.7 |
503 |
0.00918 |
0.00192 |
0.005430 |
0.01290 |
| 2.8 |
633 |
0.00919 |
0.00192 |
0.005430 |
0.01300 |
| 2.9 |
796 |
0.00919 |
0.00192 |
0.005430 |
0.01300 |
| 3.0 |
1000 |
0.00919 |
0.00192 |
0.005430 |
0.01300 |
| 3.1 |
1260 |
0.00896 |
0.00190 |
0.005230 |
0.01270 |
| 3.2 |
1590 |
0.00899 |
0.00190 |
0.005250 |
0.01270 |
| 3.3 |
2000 |
0.00831 |
0.00185 |
0.004680 |
0.01190 |
| 3.4 |
2520 |
0.00835 |
0.00186 |
0.004700 |
0.01200 |
| 3.5 |
3170 |
0.00808 |
0.00183 |
0.004500 |
0.01170 |
| 3.6 |
3990 |
0.00763 |
0.00178 |
0.004140 |
0.01110 |
| 3.7 |
5030 |
0.00653 |
0.00162 |
0.003350 |
0.00971 |
| 3.8 |
6330 |
0.00626 |
0.00159 |
0.003140 |
0.00937 |
| 3.9 |
7960 |
0.00527 |
0.00146 |
0.002410 |
0.00813 |
| 4.0 |
10000 |
0.00573 |
0.00158 |
0.002620 |
0.00883 |
| 4.1 |
12600 |
0.00433 |
0.00141 |
0.001560 |
0.00709 |
| 4.2 |
15900 |
0.00410 |
0.00140 |
0.001350 |
0.00684 |
| 4.3 |
20000 |
0.00373 |
0.00142 |
0.000945 |
0.00652 |
| 4.4 |
25200 |
0.00251 |
0.00107 |
0.000410 |
0.00462 |
| 4.5 |
31700 |
0.00282 |
0.00127 |
0.000326 |
0.00532 |
| 4.6 |
39900 |
0.00246 |
0.00120 |
0.000118 |
0.00481 |
| 4.7 |
50300 |
0.00220 |
0.00126 |
-0.000264 |
0.00466 |
| 4.8 |
63300 |
0.00186 |
0.00130 |
-0.000691 |
0.00442 |
Monotone

| 2.4 |
252 |
0.00000 |
0.00916 |
0.00139 |
0.006440 |
0.01190 |
| 2.5 |
317 |
0.00380 |
0.00916 |
0.00192 |
0.005410 |
0.01290 |
| 2.6 |
399 |
0.00380 |
0.00916 |
0.00192 |
0.005410 |
0.01290 |
| 2.7 |
503 |
0.00380 |
0.00916 |
0.00192 |
0.005410 |
0.01290 |
| 2.8 |
633 |
0.00430 |
0.00916 |
0.00192 |
0.005400 |
0.01290 |
| 2.9 |
796 |
0.00430 |
0.00916 |
0.00192 |
0.005400 |
0.01290 |
| 3.0 |
1000 |
0.00430 |
0.00916 |
0.00192 |
0.005400 |
0.01290 |
| 3.1 |
1260 |
0.00905 |
0.00897 |
0.00190 |
0.005240 |
0.01270 |
| 3.2 |
1590 |
0.01100 |
0.00897 |
0.00190 |
0.005240 |
0.01270 |
| 3.3 |
2000 |
0.08490 |
0.00833 |
0.00185 |
0.004700 |
0.01200 |
| 3.4 |
2520 |
0.09040 |
0.00833 |
0.00186 |
0.004680 |
0.01200 |
| 3.5 |
3170 |
0.09320 |
0.00808 |
0.00183 |
0.004500 |
0.01170 |
| 3.6 |
3990 |
0.12100 |
0.00763 |
0.00178 |
0.004140 |
0.01110 |
| 3.7 |
5030 |
0.14700 |
0.00653 |
0.00162 |
0.003350 |
0.00971 |
| 3.8 |
6330 |
0.15100 |
0.00626 |
0.00159 |
0.003140 |
0.00937 |
| 3.9 |
7960 |
0.18500 |
0.00549 |
0.00146 |
0.002630 |
0.00835 |
| 4.0 |
10000 |
0.26100 |
0.00549 |
0.00158 |
0.002390 |
0.00860 |
| 4.1 |
12600 |
0.33400 |
0.00433 |
0.00141 |
0.001560 |
0.00709 |
| 4.2 |
15900 |
0.36300 |
0.00410 |
0.00140 |
0.001350 |
0.00684 |
| 4.3 |
20000 |
0.43700 |
0.00373 |
0.00142 |
0.000944 |
0.00652 |
| 4.4 |
25200 |
0.45000 |
0.00267 |
0.00107 |
0.000565 |
0.00477 |
| 4.5 |
31700 |
0.51500 |
0.00267 |
0.00127 |
0.000171 |
0.00517 |
| 4.6 |
39900 |
0.55000 |
0.00246 |
0.00120 |
0.000118 |
0.00481 |
| 4.7 |
50300 |
0.61100 |
0.00220 |
0.00126 |
-0.000264 |
0.00466 |
| 4.8 |
63300 |
0.65400 |
0.00186 |
0.00130 |
-0.000691 |
0.00442 |
Vaccine (change)
Unscaled (not monotone)

| -1.3100 |
0.0489 |
0.00584 |
0.00131 |
0.003280 |
0.00841 |
| -1.2100 |
0.0616 |
0.00590 |
0.00132 |
0.003310 |
0.00849 |
| -1.1100 |
0.0776 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -1.0100 |
0.0976 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.9100 |
0.1230 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.8100 |
0.1550 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.7100 |
0.1950 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.6100 |
0.2450 |
0.00603 |
0.00138 |
0.003330 |
0.00874 |
| -0.5100 |
0.3090 |
0.00603 |
0.00138 |
0.003330 |
0.00874 |
| -0.4100 |
0.3890 |
0.00603 |
0.00138 |
0.003330 |
0.00874 |
| -0.3100 |
0.4890 |
0.00606 |
0.00137 |
0.003380 |
0.00875 |
| -0.2100 |
0.6160 |
0.00606 |
0.00137 |
0.003380 |
0.00875 |
| -0.1100 |
0.7760 |
0.00615 |
0.00139 |
0.003430 |
0.00888 |
| -0.0104 |
0.9760 |
0.00622 |
0.00140 |
0.003460 |
0.00897 |
| 0.0896 |
1.2300 |
0.00601 |
0.00138 |
0.003300 |
0.00872 |
| 0.1900 |
1.5500 |
0.00579 |
0.00136 |
0.003130 |
0.00846 |
| 0.2900 |
1.9500 |
0.00600 |
0.00142 |
0.003210 |
0.00878 |
| 0.3900 |
2.4500 |
0.00610 |
0.00145 |
0.003250 |
0.00895 |
| 0.4900 |
3.0900 |
0.00628 |
0.00151 |
0.003330 |
0.00924 |
| 0.5900 |
3.8900 |
0.00642 |
0.00163 |
0.003220 |
0.00962 |
| 0.6900 |
4.8900 |
0.00727 |
0.00199 |
0.003380 |
0.01120 |
| 0.7900 |
6.1600 |
0.00729 |
0.00197 |
0.003430 |
0.01120 |
| 0.8900 |
7.7600 |
0.00783 |
0.00216 |
0.003600 |
0.01210 |
| 0.9900 |
9.7600 |
0.00794 |
0.00215 |
0.003730 |
0.01220 |
| 1.0900 |
12.3000 |
0.00873 |
0.00238 |
0.004070 |
0.01340 |
| 1.1900 |
15.5000 |
0.00787 |
0.00226 |
0.003430 |
0.01230 |
| 1.2900 |
19.5000 |
0.00813 |
0.00252 |
0.003190 |
0.01310 |
| 1.3900 |
24.5000 |
0.00693 |
0.00246 |
0.002100 |
0.01180 |
| 1.4900 |
30.9000 |
0.00743 |
0.00263 |
0.002270 |
0.01260 |
| 1.5900 |
38.9000 |
0.00657 |
0.00266 |
0.001360 |
0.01180 |
| 1.6900 |
48.9000 |
0.00596 |
0.00327 |
-0.000448 |
0.01240 |
| 1.7900 |
61.6000 |
0.00797 |
0.00487 |
-0.001580 |
0.01750 |
| 1.8900 |
77.6000 |
0.01090 |
0.00622 |
-0.001340 |
0.02310 |
| 1.9900 |
97.6000 |
0.01540 |
0.00967 |
-0.003590 |
0.03430 |
| 2.0900 |
123.0000 |
0.01770 |
0.00974 |
-0.001400 |
0.03680 |
| 2.1900 |
155.0000 |
0.01600 |
0.00976 |
-0.003100 |
0.03520 |
Unscaled (monotone)

| -1.3100 |
0.0489 |
0.00000 |
0.00648 |
0.00131 |
3.92e-03 |
0.00904 |
| -1.2100 |
0.0616 |
0.00583 |
0.00648 |
0.00132 |
3.89e-03 |
0.00907 |
| -1.1100 |
0.0776 |
0.00692 |
0.00648 |
0.00133 |
3.87e-03 |
0.00909 |
| -1.0100 |
0.0976 |
0.00692 |
0.00648 |
0.00133 |
3.87e-03 |
0.00909 |
| -0.9100 |
0.1230 |
0.00692 |
0.00648 |
0.00133 |
3.87e-03 |
0.00909 |
| -0.8100 |
0.1550 |
0.00692 |
0.00648 |
0.00133 |
3.87e-03 |
0.00909 |
| -0.7100 |
0.1950 |
0.00692 |
0.00648 |
0.00133 |
3.87e-03 |
0.00909 |
| -0.6100 |
0.2450 |
0.01970 |
0.00648 |
0.00138 |
3.78e-03 |
0.00918 |
| -0.5100 |
0.3090 |
0.01970 |
0.00648 |
0.00138 |
3.78e-03 |
0.00918 |
| -0.4100 |
0.3890 |
0.01970 |
0.00648 |
0.00138 |
3.78e-03 |
0.00918 |
| -0.3100 |
0.4890 |
0.02920 |
0.00648 |
0.00137 |
3.80e-03 |
0.00916 |
| -0.2100 |
0.6160 |
0.03030 |
0.00648 |
0.00137 |
3.80e-03 |
0.00916 |
| -0.1100 |
0.7760 |
0.05590 |
0.00648 |
0.00139 |
3.75e-03 |
0.00921 |
| -0.0104 |
0.9760 |
0.07390 |
0.00648 |
0.00140 |
3.73e-03 |
0.00923 |
| 0.0896 |
1.2300 |
0.08690 |
0.00648 |
0.00138 |
3.77e-03 |
0.00919 |
| 0.1900 |
1.5500 |
0.09480 |
0.00648 |
0.00136 |
3.81e-03 |
0.00915 |
| 0.2900 |
1.9500 |
0.13100 |
0.00648 |
0.00142 |
3.69e-03 |
0.00927 |
| 0.3900 |
2.4500 |
0.14900 |
0.00648 |
0.00145 |
3.63e-03 |
0.00933 |
| 0.4900 |
3.0900 |
0.17100 |
0.00648 |
0.00151 |
3.52e-03 |
0.00944 |
| 0.5900 |
3.8900 |
0.21500 |
0.00648 |
0.00163 |
3.28e-03 |
0.00968 |
| 0.6900 |
4.8900 |
0.28900 |
0.00648 |
0.00199 |
2.59e-03 |
0.01040 |
| 0.7900 |
6.1600 |
0.29700 |
0.00648 |
0.00197 |
2.61e-03 |
0.01030 |
| 0.8900 |
7.7600 |
0.35200 |
0.00648 |
0.00216 |
2.25e-03 |
0.01070 |
| 0.9900 |
9.7600 |
0.37800 |
0.00648 |
0.00215 |
2.26e-03 |
0.01070 |
| 1.0900 |
12.3000 |
0.39400 |
0.00648 |
0.00238 |
1.82e-03 |
0.01110 |
| 1.1900 |
15.5000 |
0.43200 |
0.00648 |
0.00226 |
2.04e-03 |
0.01090 |
| 1.2900 |
19.5000 |
0.48200 |
0.00648 |
0.00252 |
1.54e-03 |
0.01140 |
| 1.3900 |
24.5000 |
0.58600 |
0.00648 |
0.00246 |
1.65e-03 |
0.01130 |
| 1.4900 |
30.9000 |
0.63100 |
0.00648 |
0.00263 |
1.32e-03 |
0.01160 |
| 1.5900 |
38.9000 |
0.65800 |
0.00648 |
0.00266 |
1.27e-03 |
0.01170 |
| 1.6900 |
48.9000 |
0.71800 |
0.00648 |
0.00327 |
7.01e-05 |
0.01290 |
| 1.7900 |
61.6000 |
0.76200 |
0.00648 |
0.00487 |
-3.07e-03 |
0.01600 |
| 1.8900 |
77.6000 |
0.79500 |
0.00648 |
0.00622 |
-5.72e-03 |
0.01870 |
| 1.9900 |
97.6000 |
0.85000 |
0.00648 |
0.00967 |
-1.25e-02 |
0.02540 |
| 2.0900 |
123.0000 |
0.91500 |
0.00648 |
0.00974 |
-1.26e-02 |
0.02560 |
| 2.1900 |
155.0000 |
0.91800 |
0.00648 |
0.00976 |
-1.26e-02 |
0.02560 |
VE scale (1 minus risk / placebo risk) (monotone)

| -1.3100 |
0.0489 |
0.281 |
0.179 |
-0.0687 |
0.631 |
| -1.2100 |
0.0616 |
0.281 |
0.181 |
-0.0726 |
0.635 |
| -1.1100 |
0.0776 |
0.281 |
0.182 |
-0.0745 |
0.637 |
| -1.0100 |
0.0976 |
0.281 |
0.182 |
-0.0745 |
0.637 |
| -0.9100 |
0.1230 |
0.281 |
0.182 |
-0.0745 |
0.637 |
| -0.8100 |
0.1550 |
0.281 |
0.182 |
-0.0745 |
0.637 |
| -0.7100 |
0.1950 |
0.281 |
0.182 |
-0.0745 |
0.637 |
| -0.6100 |
0.2450 |
0.281 |
0.188 |
-0.0875 |
0.650 |
| -0.5100 |
0.3090 |
0.281 |
0.188 |
-0.0875 |
0.650 |
| -0.4100 |
0.3890 |
0.281 |
0.188 |
-0.0875 |
0.650 |
| -0.3100 |
0.4890 |
0.281 |
0.187 |
-0.0852 |
0.648 |
| -0.2100 |
0.6160 |
0.281 |
0.187 |
-0.0852 |
0.648 |
| -0.1100 |
0.7760 |
0.281 |
0.190 |
-0.0912 |
0.654 |
| -0.0104 |
0.9760 |
0.281 |
0.192 |
-0.0946 |
0.657 |
| 0.0896 |
1.2300 |
0.281 |
0.189 |
-0.0883 |
0.651 |
| 0.1900 |
1.5500 |
0.281 |
0.186 |
-0.0827 |
0.645 |
| 0.2900 |
1.9500 |
0.281 |
0.194 |
-0.0992 |
0.662 |
| 0.3900 |
2.4500 |
0.281 |
0.198 |
-0.1070 |
0.670 |
| 0.4900 |
3.0900 |
0.281 |
0.206 |
-0.1220 |
0.685 |
| 0.5900 |
3.8900 |
0.281 |
0.223 |
-0.1560 |
0.718 |
| 0.6900 |
4.8900 |
0.281 |
0.271 |
-0.2510 |
0.813 |
| 0.7900 |
6.1600 |
0.281 |
0.269 |
-0.2470 |
0.809 |
| 0.8900 |
7.7600 |
0.281 |
0.295 |
-0.2970 |
0.859 |
| 0.9900 |
9.7600 |
0.281 |
0.294 |
-0.2940 |
0.857 |
| 1.0900 |
12.3000 |
0.281 |
0.324 |
-0.3550 |
0.917 |
| 1.1900 |
15.5000 |
0.281 |
0.309 |
-0.3240 |
0.887 |
| 1.2900 |
19.5000 |
0.281 |
0.344 |
-0.3940 |
0.956 |
| 1.3900 |
24.5000 |
0.281 |
0.336 |
-0.3780 |
0.940 |
| 1.4900 |
30.9000 |
0.281 |
0.360 |
-0.4240 |
0.987 |
| 1.5900 |
38.9000 |
0.281 |
0.363 |
-0.4300 |
0.993 |
| 1.6900 |
48.9000 |
0.281 |
0.447 |
-0.5940 |
1.160 |
| 1.7900 |
61.6000 |
0.281 |
0.665 |
-1.0200 |
1.590 |
| 1.8900 |
77.6000 |
0.281 |
0.850 |
-1.3800 |
1.950 |
| 1.9900 |
97.6000 |
0.281 |
1.320 |
-2.3100 |
2.870 |
| 2.0900 |
123.0000 |
0.281 |
1.330 |
-2.3200 |
2.890 |
| 2.1900 |
155.0000 |
0.281 |
1.330 |
-2.3300 |
2.890 |
IgG Spike Delta2
Vaccine
Unscaled (not monotone)

| 3.2 |
1580 |
0.00522 |
0.00105 |
3.17e-03 |
0.00727 |
| 3.3 |
1990 |
0.00594 |
0.00134 |
3.32e-03 |
0.00855 |
| 3.4 |
2510 |
0.00594 |
0.00134 |
3.32e-03 |
0.00855 |
| 3.5 |
3150 |
0.00594 |
0.00134 |
3.32e-03 |
0.00855 |
| 3.6 |
3970 |
0.00594 |
0.00134 |
3.32e-03 |
0.00855 |
| 3.7 |
5000 |
0.00594 |
0.00134 |
3.32e-03 |
0.00855 |
| 3.8 |
6290 |
0.00599 |
0.00136 |
3.33e-03 |
0.00865 |
| 3.9 |
7920 |
0.00599 |
0.00136 |
3.33e-03 |
0.00866 |
| 4.0 |
9970 |
0.00599 |
0.00136 |
3.33e-03 |
0.00866 |
| 4.1 |
12600 |
0.00601 |
0.00136 |
3.35e-03 |
0.00867 |
| 4.2 |
15800 |
0.00608 |
0.00138 |
3.37e-03 |
0.00878 |
| 4.3 |
19900 |
0.00609 |
0.00138 |
3.39e-03 |
0.00880 |
| 4.4 |
25100 |
0.00621 |
0.00143 |
3.41e-03 |
0.00900 |
| 4.5 |
31500 |
0.00625 |
0.00141 |
3.49e-03 |
0.00901 |
| 4.6 |
39700 |
0.00631 |
0.00143 |
3.51e-03 |
0.00911 |
| 4.7 |
50000 |
0.00641 |
0.00146 |
3.55e-03 |
0.00926 |
| 4.8 |
62900 |
0.00646 |
0.00146 |
3.59e-03 |
0.00933 |
| 4.9 |
79200 |
0.00665 |
0.00151 |
3.68e-03 |
0.00961 |
| 5.0 |
99700 |
0.00658 |
0.00153 |
3.58e-03 |
0.00958 |
| 5.1 |
126000 |
0.00670 |
0.00162 |
3.54e-03 |
0.00987 |
| 5.2 |
158000 |
0.00684 |
0.00171 |
3.48e-03 |
0.01020 |
| 5.3 |
199000 |
0.00623 |
0.00171 |
2.87e-03 |
0.00958 |
| 5.4 |
251000 |
0.00667 |
0.00199 |
2.77e-03 |
0.01060 |
| 5.5 |
315000 |
0.00483 |
0.00173 |
1.44e-03 |
0.00823 |
| 5.6 |
397000 |
0.00338 |
0.00137 |
6.94e-04 |
0.00606 |
| 5.7 |
500000 |
0.00228 |
0.00121 |
-8.78e-05 |
0.00465 |
Unscaled (monotone)

| 3.2 |
1580 |
0.0000 |
0.00617 |
0.00105 |
4.12e-03 |
0.00822 |
| 3.3 |
1990 |
0.0117 |
0.00617 |
0.00134 |
3.56e-03 |
0.00879 |
| 3.4 |
2510 |
0.0117 |
0.00617 |
0.00134 |
3.56e-03 |
0.00879 |
| 3.5 |
3150 |
0.0117 |
0.00617 |
0.00134 |
3.56e-03 |
0.00879 |
| 3.6 |
3970 |
0.0117 |
0.00617 |
0.00134 |
3.56e-03 |
0.00879 |
| 3.7 |
5000 |
0.0117 |
0.00617 |
0.00134 |
3.56e-03 |
0.00879 |
| 3.8 |
6290 |
0.0175 |
0.00617 |
0.00136 |
3.51e-03 |
0.00883 |
| 3.9 |
7920 |
0.0180 |
0.00617 |
0.00136 |
3.51e-03 |
0.00884 |
| 4.0 |
9970 |
0.0180 |
0.00617 |
0.00136 |
3.51e-03 |
0.00884 |
| 4.1 |
12600 |
0.0244 |
0.00617 |
0.00136 |
3.51e-03 |
0.00883 |
| 4.2 |
15800 |
0.0313 |
0.00617 |
0.00138 |
3.47e-03 |
0.00888 |
| 4.3 |
19900 |
0.0371 |
0.00617 |
0.00138 |
3.47e-03 |
0.00888 |
| 4.4 |
25100 |
0.0457 |
0.00617 |
0.00143 |
3.38e-03 |
0.00897 |
| 4.5 |
31500 |
0.0680 |
0.00617 |
0.00141 |
3.41e-03 |
0.00893 |
| 4.6 |
39700 |
0.0749 |
0.00617 |
0.00143 |
3.38e-03 |
0.00897 |
| 4.7 |
50000 |
0.0915 |
0.00617 |
0.00146 |
3.32e-03 |
0.00903 |
| 4.8 |
62900 |
0.1070 |
0.00617 |
0.00146 |
3.31e-03 |
0.00904 |
| 4.9 |
79200 |
0.1350 |
0.00617 |
0.00151 |
3.21e-03 |
0.00914 |
| 5.0 |
99700 |
0.1720 |
0.00617 |
0.00153 |
3.17e-03 |
0.00918 |
| 5.1 |
126000 |
0.2040 |
0.00617 |
0.00162 |
3.01e-03 |
0.00934 |
| 5.2 |
158000 |
0.2640 |
0.00617 |
0.00171 |
2.81e-03 |
0.00953 |
| 5.3 |
199000 |
0.3030 |
0.00617 |
0.00171 |
2.82e-03 |
0.00953 |
| 5.4 |
251000 |
0.4580 |
0.00617 |
0.00199 |
2.28e-03 |
0.01010 |
| 5.5 |
315000 |
0.5610 |
0.00483 |
0.00173 |
1.44e-03 |
0.00823 |
| 5.6 |
397000 |
0.6750 |
0.00338 |
0.00137 |
6.94e-04 |
0.00606 |
| 5.7 |
500000 |
0.7520 |
0.00228 |
0.00121 |
-8.79e-05 |
0.00465 |
VE scale (1 minus risk / placebo risk) (monotone)

| 3.2 |
1580 |
0.315 |
0.157 |
0.00792 |
0.623 |
| 3.3 |
1990 |
0.315 |
0.182 |
-0.04110 |
0.672 |
| 3.4 |
2510 |
0.315 |
0.182 |
-0.04110 |
0.672 |
| 3.5 |
3150 |
0.315 |
0.182 |
-0.04110 |
0.672 |
| 3.6 |
3970 |
0.315 |
0.182 |
-0.04110 |
0.672 |
| 3.7 |
5000 |
0.315 |
0.182 |
-0.04110 |
0.672 |
| 3.8 |
6290 |
0.315 |
0.184 |
-0.04490 |
0.676 |
| 3.9 |
7920 |
0.315 |
0.184 |
-0.04530 |
0.676 |
| 4.0 |
9970 |
0.315 |
0.184 |
-0.04530 |
0.676 |
| 4.1 |
12600 |
0.315 |
0.184 |
-0.04480 |
0.676 |
| 4.2 |
15800 |
0.315 |
0.186 |
-0.04930 |
0.680 |
| 4.3 |
19900 |
0.315 |
0.186 |
-0.04900 |
0.680 |
| 4.4 |
25100 |
0.315 |
0.190 |
-0.05720 |
0.688 |
| 4.5 |
31500 |
0.315 |
0.188 |
-0.05400 |
0.685 |
| 4.6 |
39700 |
0.315 |
0.190 |
-0.05750 |
0.688 |
| 4.7 |
50000 |
0.315 |
0.193 |
-0.06270 |
0.694 |
| 4.8 |
62900 |
0.315 |
0.194 |
-0.06410 |
0.695 |
| 4.9 |
79200 |
0.315 |
0.198 |
-0.07300 |
0.704 |
| 5.0 |
99700 |
0.315 |
0.200 |
-0.07670 |
0.708 |
| 5.1 |
126000 |
0.315 |
0.208 |
-0.09220 |
0.723 |
| 5.2 |
158000 |
0.315 |
0.217 |
-0.11100 |
0.742 |
| 5.3 |
199000 |
0.315 |
0.217 |
-0.11000 |
0.741 |
| 5.4 |
251000 |
0.315 |
0.245 |
-0.16400 |
0.795 |
| 5.5 |
315000 |
0.464 |
0.209 |
0.05350 |
0.874 |
| 5.6 |
397000 |
0.626 |
0.162 |
0.30700 |
0.944 |
| 5.7 |
500000 |
0.747 |
0.140 |
0.47300 |
1.020 |
Placebo
Not monotone

| 2.4 |
252 |
0.00902 |
0.00139 |
0.006290 |
0.01170 |
| 2.5 |
317 |
0.00919 |
0.00192 |
0.005430 |
0.01300 |
| 2.6 |
399 |
0.00919 |
0.00192 |
0.005430 |
0.01300 |
| 2.7 |
503 |
0.00919 |
0.00192 |
0.005430 |
0.01300 |
| 2.8 |
633 |
0.00919 |
0.00192 |
0.005430 |
0.01300 |
| 2.9 |
796 |
0.00919 |
0.00192 |
0.005430 |
0.01300 |
| 3.0 |
1000 |
0.00919 |
0.00192 |
0.005430 |
0.01300 |
| 3.1 |
1260 |
0.00923 |
0.00194 |
0.005430 |
0.01300 |
| 3.2 |
1590 |
0.00898 |
0.00190 |
0.005240 |
0.01270 |
| 3.3 |
2000 |
0.00810 |
0.00179 |
0.004580 |
0.01160 |
| 3.4 |
2520 |
0.00834 |
0.00186 |
0.004690 |
0.01200 |
| 3.5 |
3170 |
0.00806 |
0.00182 |
0.004490 |
0.01160 |
| 3.6 |
3990 |
0.00783 |
0.00180 |
0.004310 |
0.01130 |
| 3.7 |
5030 |
0.00713 |
0.00171 |
0.003770 |
0.01050 |
| 3.8 |
6330 |
0.00625 |
0.00159 |
0.003140 |
0.00936 |
| 3.9 |
7960 |
0.00616 |
0.00160 |
0.003020 |
0.00931 |
| 4.0 |
10000 |
0.00555 |
0.00154 |
0.002540 |
0.00856 |
| 4.1 |
12600 |
0.00492 |
0.00148 |
0.002020 |
0.00782 |
| 4.2 |
15900 |
0.00439 |
0.00143 |
0.001580 |
0.00720 |
| 4.3 |
20000 |
0.00366 |
0.00139 |
0.000941 |
0.00637 |
| 4.4 |
25200 |
0.00312 |
0.00126 |
0.000656 |
0.00559 |
| 4.5 |
31700 |
0.00272 |
0.00120 |
0.000370 |
0.00506 |
| 4.6 |
39900 |
0.00282 |
0.00124 |
0.000383 |
0.00526 |
| 4.7 |
50300 |
0.00208 |
0.00114 |
-0.000158 |
0.00431 |
| 4.8 |
63300 |
0.00182 |
0.00123 |
-0.000587 |
0.00424 |
Monotone

| 2.4 |
252 |
0.00000 |
0.00917 |
0.00139 |
0.006450 |
0.01190 |
| 2.5 |
317 |
0.00430 |
0.00917 |
0.00192 |
0.005410 |
0.01290 |
| 2.6 |
399 |
0.00430 |
0.00917 |
0.00192 |
0.005410 |
0.01290 |
| 2.7 |
503 |
0.00430 |
0.00917 |
0.00192 |
0.005410 |
0.01290 |
| 2.8 |
633 |
0.00430 |
0.00917 |
0.00192 |
0.005410 |
0.01290 |
| 2.9 |
796 |
0.00430 |
0.00917 |
0.00192 |
0.005410 |
0.01290 |
| 3.0 |
1000 |
0.00430 |
0.00917 |
0.00192 |
0.005410 |
0.01290 |
| 3.1 |
1260 |
0.00878 |
0.00917 |
0.00194 |
0.005380 |
0.01300 |
| 3.2 |
1590 |
0.01050 |
0.00898 |
0.00190 |
0.005240 |
0.01270 |
| 3.3 |
2000 |
0.05470 |
0.00821 |
0.00179 |
0.004700 |
0.01170 |
| 3.4 |
2520 |
0.08790 |
0.00821 |
0.00186 |
0.004570 |
0.01190 |
| 3.5 |
3170 |
0.09240 |
0.00806 |
0.00182 |
0.004490 |
0.01160 |
| 3.6 |
3990 |
0.09590 |
0.00783 |
0.00180 |
0.004310 |
0.01130 |
| 3.7 |
5030 |
0.14500 |
0.00713 |
0.00171 |
0.003770 |
0.01050 |
| 3.8 |
6330 |
0.15000 |
0.00625 |
0.00159 |
0.003140 |
0.00936 |
| 3.9 |
7960 |
0.16200 |
0.00616 |
0.00160 |
0.003020 |
0.00931 |
| 4.0 |
10000 |
0.24400 |
0.00555 |
0.00154 |
0.002540 |
0.00856 |
| 4.1 |
12600 |
0.27900 |
0.00492 |
0.00148 |
0.002020 |
0.00782 |
| 4.2 |
15900 |
0.34300 |
0.00439 |
0.00143 |
0.001580 |
0.00720 |
| 4.3 |
20000 |
0.42200 |
0.00366 |
0.00139 |
0.000941 |
0.00637 |
| 4.4 |
25200 |
0.44200 |
0.00312 |
0.00126 |
0.000656 |
0.00559 |
| 4.5 |
31700 |
0.48900 |
0.00277 |
0.00120 |
0.000423 |
0.00512 |
| 4.6 |
39900 |
0.54300 |
0.00277 |
0.00124 |
0.000331 |
0.00521 |
| 4.7 |
50300 |
0.57900 |
0.00208 |
0.00114 |
-0.000158 |
0.00431 |
| 4.8 |
63300 |
0.64200 |
0.00182 |
0.00123 |
-0.000587 |
0.00424 |
Vaccine (change)
Unscaled (not monotone)

| -1.2700 |
0.0535 |
0.00584 |
0.00131 |
0.003280 |
0.00841 |
| -1.1700 |
0.0674 |
0.00590 |
0.00132 |
0.003310 |
0.00849 |
| -1.0700 |
0.0848 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.9710 |
0.1070 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.8710 |
0.1340 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.7710 |
0.1690 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.6710 |
0.2130 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.5710 |
0.2680 |
0.00603 |
0.00138 |
0.003330 |
0.00874 |
| -0.4710 |
0.3380 |
0.00603 |
0.00138 |
0.003330 |
0.00874 |
| -0.3710 |
0.4250 |
0.00603 |
0.00138 |
0.003330 |
0.00874 |
| -0.2710 |
0.5350 |
0.00606 |
0.00137 |
0.003380 |
0.00875 |
| -0.1710 |
0.6740 |
0.00612 |
0.00139 |
0.003400 |
0.00883 |
| -0.0715 |
0.8480 |
0.00615 |
0.00139 |
0.003430 |
0.00888 |
| 0.0285 |
1.0700 |
0.00596 |
0.00137 |
0.003270 |
0.00865 |
| 0.1290 |
1.3400 |
0.00579 |
0.00136 |
0.003130 |
0.00845 |
| 0.2290 |
1.6900 |
0.00584 |
0.00137 |
0.003140 |
0.00853 |
| 0.3290 |
2.1300 |
0.00600 |
0.00142 |
0.003210 |
0.00879 |
| 0.4290 |
2.6800 |
0.00611 |
0.00145 |
0.003260 |
0.00895 |
| 0.5290 |
3.3800 |
0.00606 |
0.00148 |
0.003140 |
0.00897 |
| 0.6290 |
4.2500 |
0.00669 |
0.00174 |
0.003280 |
0.01010 |
| 0.7290 |
5.3500 |
0.00728 |
0.00197 |
0.003420 |
0.01110 |
| 0.8290 |
6.7400 |
0.00746 |
0.00201 |
0.003530 |
0.01140 |
| 0.9290 |
8.4800 |
0.00781 |
0.00216 |
0.003580 |
0.01200 |
| 1.0300 |
10.7000 |
0.00799 |
0.00217 |
0.003750 |
0.01220 |
| 1.1300 |
13.4000 |
0.00852 |
0.00240 |
0.003810 |
0.01320 |
| 1.2300 |
16.9000 |
0.00717 |
0.00207 |
0.003110 |
0.01120 |
| 1.3300 |
21.3000 |
0.00738 |
0.00223 |
0.003000 |
0.01180 |
| 1.4300 |
26.8000 |
0.00701 |
0.00248 |
0.002150 |
0.01190 |
| 1.5300 |
33.8000 |
0.00676 |
0.00249 |
0.001880 |
0.01160 |
| 1.6300 |
42.5000 |
0.00657 |
0.00265 |
0.001380 |
0.01180 |
| 1.7300 |
53.5000 |
0.00654 |
0.00298 |
0.000701 |
0.01240 |
| 1.8300 |
67.4000 |
0.00687 |
0.00540 |
-0.003720 |
0.01750 |
| 1.9300 |
84.8000 |
0.01170 |
0.00621 |
-0.000465 |
0.02390 |
| 2.0300 |
107.0000 |
0.01010 |
0.00587 |
-0.001400 |
0.02160 |
| 2.1300 |
134.0000 |
0.01710 |
0.00944 |
-0.001440 |
0.03560 |
| 2.2300 |
169.0000 |
0.01770 |
0.01060 |
-0.003040 |
0.03840 |
Unscaled (monotone)

| -1.2700 |
0.0535 |
0.00000 |
0.00641 |
0.00131 |
0.003850 |
0.00897 |
| -1.1700 |
0.0674 |
0.00583 |
0.00641 |
0.00132 |
0.003820 |
0.00900 |
| -1.0700 |
0.0848 |
0.00692 |
0.00641 |
0.00133 |
0.003800 |
0.00901 |
| -0.9710 |
0.1070 |
0.00692 |
0.00641 |
0.00133 |
0.003800 |
0.00901 |
| -0.8710 |
0.1340 |
0.00692 |
0.00641 |
0.00133 |
0.003800 |
0.00901 |
| -0.7710 |
0.1690 |
0.00692 |
0.00641 |
0.00133 |
0.003800 |
0.00901 |
| -0.6710 |
0.2130 |
0.00692 |
0.00641 |
0.00133 |
0.003800 |
0.00901 |
| -0.5710 |
0.2680 |
0.01970 |
0.00641 |
0.00138 |
0.003710 |
0.00911 |
| -0.4710 |
0.3380 |
0.01970 |
0.00641 |
0.00138 |
0.003710 |
0.00911 |
| -0.3710 |
0.4250 |
0.01970 |
0.00641 |
0.00138 |
0.003710 |
0.00911 |
| -0.2710 |
0.5350 |
0.02980 |
0.00641 |
0.00137 |
0.003720 |
0.00909 |
| -0.1710 |
0.6740 |
0.04050 |
0.00641 |
0.00139 |
0.003690 |
0.00912 |
| -0.0715 |
0.8480 |
0.05590 |
0.00641 |
0.00139 |
0.003680 |
0.00914 |
| 0.0285 |
1.0700 |
0.07420 |
0.00641 |
0.00137 |
0.003720 |
0.00910 |
| 0.1290 |
1.3400 |
0.09320 |
0.00641 |
0.00136 |
0.003750 |
0.00907 |
| 0.2290 |
1.6900 |
0.10000 |
0.00641 |
0.00137 |
0.003720 |
0.00910 |
| 0.3290 |
2.1300 |
0.13200 |
0.00641 |
0.00142 |
0.003620 |
0.00920 |
| 0.4290 |
2.6800 |
0.14900 |
0.00641 |
0.00145 |
0.003560 |
0.00926 |
| 0.5290 |
3.3800 |
0.18400 |
0.00641 |
0.00148 |
0.003500 |
0.00932 |
| 0.6290 |
4.2500 |
0.23300 |
0.00641 |
0.00174 |
0.003010 |
0.00981 |
| 0.7290 |
5.3500 |
0.29400 |
0.00641 |
0.00197 |
0.002550 |
0.01030 |
| 0.8290 |
6.7400 |
0.32200 |
0.00641 |
0.00201 |
0.002480 |
0.01030 |
| 0.9290 |
8.4800 |
0.34900 |
0.00641 |
0.00216 |
0.002180 |
0.01060 |
| 1.0300 |
10.7000 |
0.38400 |
0.00641 |
0.00217 |
0.002160 |
0.01070 |
| 1.1300 |
13.4000 |
0.40100 |
0.00641 |
0.00240 |
0.001700 |
0.01110 |
| 1.2300 |
16.9000 |
0.42700 |
0.00641 |
0.00207 |
0.002350 |
0.01050 |
| 1.3300 |
21.3000 |
0.47200 |
0.00641 |
0.00223 |
0.002030 |
0.01080 |
| 1.4300 |
26.8000 |
0.59500 |
0.00641 |
0.00248 |
0.001550 |
0.01130 |
| 1.5300 |
33.8000 |
0.62300 |
0.00641 |
0.00249 |
0.001530 |
0.01130 |
| 1.6300 |
42.5000 |
0.65900 |
0.00641 |
0.00265 |
0.001220 |
0.01160 |
| 1.7300 |
53.5000 |
0.70400 |
0.00641 |
0.00298 |
0.000566 |
0.01230 |
| 1.8300 |
67.4000 |
0.77200 |
0.00641 |
0.00540 |
-0.004180 |
0.01700 |
| 1.9300 |
84.8000 |
0.82100 |
0.00641 |
0.00621 |
-0.005760 |
0.01860 |
| 2.0300 |
107.0000 |
0.85200 |
0.00641 |
0.00587 |
-0.005100 |
0.01790 |
| 2.1300 |
134.0000 |
0.91400 |
0.00641 |
0.00944 |
-0.012100 |
0.02490 |
| 2.2300 |
169.0000 |
0.93800 |
0.00641 |
0.01060 |
-0.014300 |
0.02710 |
VE scale (1 minus risk / placebo risk) (monotone)

| -1.2700 |
0.0535 |
0.289 |
0.178 |
-0.0594 |
0.638 |
| -1.1700 |
0.0674 |
0.289 |
0.180 |
-0.0633 |
0.642 |
| -1.0700 |
0.0848 |
0.289 |
0.181 |
-0.0652 |
0.644 |
| -0.9710 |
0.1070 |
0.289 |
0.181 |
-0.0652 |
0.644 |
| -0.8710 |
0.1340 |
0.289 |
0.181 |
-0.0652 |
0.644 |
| -0.7710 |
0.1690 |
0.289 |
0.181 |
-0.0652 |
0.644 |
| -0.6710 |
0.2130 |
0.289 |
0.181 |
-0.0652 |
0.644 |
| -0.5710 |
0.2680 |
0.289 |
0.188 |
-0.0782 |
0.657 |
| -0.4710 |
0.3380 |
0.289 |
0.188 |
-0.0782 |
0.657 |
| -0.3710 |
0.4250 |
0.289 |
0.188 |
-0.0782 |
0.657 |
| -0.2710 |
0.5350 |
0.289 |
0.186 |
-0.0759 |
0.655 |
| -0.1710 |
0.6740 |
0.289 |
0.189 |
-0.0802 |
0.659 |
| -0.0715 |
0.8480 |
0.289 |
0.189 |
-0.0818 |
0.660 |
| 0.0285 |
1.0700 |
0.289 |
0.187 |
-0.0765 |
0.655 |
| 0.1290 |
1.3400 |
0.289 |
0.185 |
-0.0727 |
0.651 |
| 0.2290 |
1.6900 |
0.289 |
0.187 |
-0.0771 |
0.656 |
| 0.3290 |
2.1300 |
0.289 |
0.194 |
-0.0903 |
0.669 |
| 0.4290 |
2.6800 |
0.289 |
0.198 |
-0.0983 |
0.677 |
| 0.5290 |
3.3800 |
0.289 |
0.202 |
-0.1070 |
0.685 |
| 0.6290 |
4.2500 |
0.289 |
0.236 |
-0.1740 |
0.752 |
| 0.7290 |
5.3500 |
0.289 |
0.268 |
-0.2360 |
0.814 |
| 0.8290 |
6.7400 |
0.289 |
0.273 |
-0.2450 |
0.824 |
| 0.9290 |
8.4800 |
0.289 |
0.293 |
-0.2850 |
0.864 |
| 1.0300 |
10.7000 |
0.289 |
0.295 |
-0.2880 |
0.867 |
| 1.1300 |
13.4000 |
0.289 |
0.327 |
-0.3510 |
0.930 |
| 1.2300 |
16.9000 |
0.289 |
0.281 |
-0.2620 |
0.841 |
| 1.3300 |
21.3000 |
0.289 |
0.304 |
-0.3060 |
0.885 |
| 1.4300 |
26.8000 |
0.289 |
0.337 |
-0.3710 |
0.950 |
| 1.5300 |
33.8000 |
0.289 |
0.338 |
-0.3740 |
0.952 |
| 1.6300 |
42.5000 |
0.289 |
0.360 |
-0.4170 |
0.995 |
| 1.7300 |
53.5000 |
0.289 |
0.406 |
-0.5060 |
1.080 |
| 1.8300 |
67.4000 |
0.289 |
0.735 |
-1.1500 |
1.730 |
| 1.9300 |
84.8000 |
0.289 |
0.845 |
-1.3700 |
1.950 |
| 2.0300 |
107.0000 |
0.289 |
0.799 |
-1.2800 |
1.850 |
| 2.1300 |
134.0000 |
0.289 |
1.280 |
-2.2300 |
2.810 |
| 2.2300 |
169.0000 |
0.289 |
1.440 |
-2.5300 |
3.110 |
IgG Spike Delta3
Vaccine
Unscaled (not monotone)

| 3.1 |
1260 |
0.00522 |
0.00105 |
0.003170 |
0.00727 |
| 3.2 |
1580 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.3 |
1990 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.4 |
2510 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.5 |
3160 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.6 |
3970 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.7 |
5000 |
0.00599 |
0.00136 |
0.003330 |
0.00865 |
| 3.8 |
6300 |
0.00599 |
0.00136 |
0.003330 |
0.00866 |
| 3.9 |
7930 |
0.00599 |
0.00136 |
0.003330 |
0.00866 |
| 4.0 |
9980 |
0.00601 |
0.00136 |
0.003350 |
0.00867 |
| 4.1 |
12600 |
0.00607 |
0.00138 |
0.003370 |
0.00878 |
| 4.2 |
15800 |
0.00609 |
0.00138 |
0.003390 |
0.00880 |
| 4.3 |
19900 |
0.00621 |
0.00143 |
0.003410 |
0.00900 |
| 4.4 |
25100 |
0.00625 |
0.00141 |
0.003490 |
0.00901 |
| 4.5 |
31600 |
0.00625 |
0.00141 |
0.003490 |
0.00901 |
| 4.6 |
39700 |
0.00633 |
0.00143 |
0.003530 |
0.00913 |
| 4.7 |
50000 |
0.00644 |
0.00146 |
0.003570 |
0.00930 |
| 4.8 |
63000 |
0.00665 |
0.00151 |
0.003680 |
0.00961 |
| 4.9 |
79300 |
0.00677 |
0.00154 |
0.003750 |
0.00980 |
| 5.0 |
99800 |
0.00661 |
0.00158 |
0.003520 |
0.00970 |
| 5.1 |
126000 |
0.00682 |
0.00171 |
0.003470 |
0.01020 |
| 5.2 |
158000 |
0.00637 |
0.00179 |
0.002870 |
0.00987 |
| 5.3 |
199000 |
0.00615 |
0.00178 |
0.002670 |
0.00963 |
| 5.4 |
251000 |
0.00547 |
0.00191 |
0.001730 |
0.00922 |
| 5.5 |
316000 |
0.00340 |
0.00138 |
0.000696 |
0.00611 |
| 5.6 |
397000 |
0.00298 |
0.00145 |
0.000143 |
0.00582 |
Unscaled (monotone)

| 3.1 |
1260 |
0.0000 |
0.00616 |
0.00105 |
0.004110 |
0.00821 |
| 3.2 |
1580 |
0.0117 |
0.00616 |
0.00134 |
0.003540 |
0.00878 |
| 3.3 |
1990 |
0.0117 |
0.00616 |
0.00134 |
0.003540 |
0.00878 |
| 3.4 |
2510 |
0.0117 |
0.00616 |
0.00134 |
0.003540 |
0.00878 |
| 3.5 |
3160 |
0.0117 |
0.00616 |
0.00134 |
0.003540 |
0.00878 |
| 3.6 |
3970 |
0.0117 |
0.00616 |
0.00134 |
0.003540 |
0.00878 |
| 3.7 |
5000 |
0.0175 |
0.00616 |
0.00136 |
0.003500 |
0.00882 |
| 3.8 |
6300 |
0.0180 |
0.00616 |
0.00136 |
0.003490 |
0.00882 |
| 3.9 |
7930 |
0.0180 |
0.00616 |
0.00136 |
0.003490 |
0.00882 |
| 4.0 |
9980 |
0.0244 |
0.00616 |
0.00136 |
0.003500 |
0.00882 |
| 4.1 |
12600 |
0.0302 |
0.00616 |
0.00138 |
0.003450 |
0.00886 |
| 4.2 |
15800 |
0.0371 |
0.00616 |
0.00138 |
0.003450 |
0.00886 |
| 4.3 |
19900 |
0.0457 |
0.00616 |
0.00143 |
0.003360 |
0.00895 |
| 4.4 |
25100 |
0.0674 |
0.00616 |
0.00141 |
0.003400 |
0.00892 |
| 4.5 |
31600 |
0.0685 |
0.00616 |
0.00141 |
0.003400 |
0.00892 |
| 4.6 |
39700 |
0.0802 |
0.00616 |
0.00143 |
0.003350 |
0.00896 |
| 4.7 |
50000 |
0.1000 |
0.00616 |
0.00146 |
0.003290 |
0.00902 |
| 4.8 |
63000 |
0.1360 |
0.00616 |
0.00151 |
0.003190 |
0.00912 |
| 4.9 |
79300 |
0.1620 |
0.00616 |
0.00154 |
0.003140 |
0.00918 |
| 5.0 |
99800 |
0.1960 |
0.00616 |
0.00158 |
0.003070 |
0.00925 |
| 5.1 |
126000 |
0.2610 |
0.00616 |
0.00171 |
0.002810 |
0.00951 |
| 5.2 |
158000 |
0.3140 |
0.00616 |
0.00179 |
0.002660 |
0.00966 |
| 5.3 |
199000 |
0.4220 |
0.00615 |
0.00178 |
0.002670 |
0.00963 |
| 5.4 |
251000 |
0.5580 |
0.00547 |
0.00191 |
0.001730 |
0.00922 |
| 5.5 |
316000 |
0.6640 |
0.00340 |
0.00138 |
0.000696 |
0.00611 |
| 5.6 |
397000 |
0.7540 |
0.00298 |
0.00145 |
0.000143 |
0.00582 |
VE scale (1 minus risk / placebo risk) (monotone)

| 3.1 |
1260 |
0.317 |
0.157 |
0.00995 |
0.624 |
| 3.2 |
1580 |
0.317 |
0.182 |
-0.03920 |
0.673 |
| 3.3 |
1990 |
0.317 |
0.182 |
-0.03920 |
0.673 |
| 3.4 |
2510 |
0.317 |
0.182 |
-0.03920 |
0.673 |
| 3.5 |
3160 |
0.317 |
0.182 |
-0.03920 |
0.673 |
| 3.6 |
3970 |
0.317 |
0.182 |
-0.03920 |
0.673 |
| 3.7 |
5000 |
0.317 |
0.184 |
-0.04290 |
0.677 |
| 3.8 |
6300 |
0.317 |
0.184 |
-0.04330 |
0.678 |
| 3.9 |
7930 |
0.317 |
0.184 |
-0.04330 |
0.678 |
| 4.0 |
9980 |
0.317 |
0.184 |
-0.04280 |
0.677 |
| 4.1 |
12600 |
0.317 |
0.186 |
-0.04730 |
0.682 |
| 4.2 |
15800 |
0.317 |
0.186 |
-0.04710 |
0.681 |
| 4.3 |
19900 |
0.317 |
0.190 |
-0.05530 |
0.690 |
| 4.4 |
25100 |
0.317 |
0.188 |
-0.05200 |
0.686 |
| 4.5 |
31600 |
0.317 |
0.188 |
-0.05210 |
0.686 |
| 4.6 |
39700 |
0.317 |
0.190 |
-0.05620 |
0.690 |
| 4.7 |
50000 |
0.317 |
0.193 |
-0.06170 |
0.696 |
| 4.8 |
63000 |
0.317 |
0.198 |
-0.07120 |
0.705 |
| 4.9 |
79300 |
0.317 |
0.201 |
-0.07660 |
0.711 |
| 5.0 |
99800 |
0.317 |
0.204 |
-0.08310 |
0.717 |
| 5.1 |
126000 |
0.317 |
0.217 |
-0.10800 |
0.742 |
| 5.2 |
158000 |
0.317 |
0.224 |
-0.12300 |
0.757 |
| 5.3 |
199000 |
0.318 |
0.223 |
-0.12000 |
0.756 |
| 5.4 |
251000 |
0.393 |
0.232 |
-0.06110 |
0.847 |
| 5.5 |
316000 |
0.623 |
0.164 |
0.30200 |
0.944 |
| 5.6 |
397000 |
0.669 |
0.169 |
0.33900 |
1.000 |
Placebo
Not monotone

| 2.4 |
252 |
0.00902 |
0.00139 |
0.006290 |
0.01170 |
| 2.5 |
317 |
0.00919 |
0.00192 |
0.005420 |
0.01290 |
| 2.6 |
399 |
0.00919 |
0.00192 |
0.005420 |
0.01290 |
| 2.7 |
503 |
0.00919 |
0.00192 |
0.005420 |
0.01290 |
| 2.8 |
633 |
0.00919 |
0.00192 |
0.005420 |
0.01290 |
| 2.9 |
796 |
0.00919 |
0.00192 |
0.005420 |
0.01290 |
| 3.0 |
1000 |
0.00919 |
0.00192 |
0.005420 |
0.01290 |
| 3.1 |
1260 |
0.00888 |
0.00190 |
0.005160 |
0.01260 |
| 3.2 |
1590 |
0.00855 |
0.00189 |
0.004850 |
0.01230 |
| 3.3 |
2000 |
0.00835 |
0.00186 |
0.004700 |
0.01200 |
| 3.4 |
2520 |
0.00806 |
0.00182 |
0.004490 |
0.01160 |
| 3.5 |
3170 |
0.00752 |
0.00175 |
0.004090 |
0.01100 |
| 3.6 |
3990 |
0.00675 |
0.00166 |
0.003500 |
0.00999 |
| 3.7 |
5030 |
0.00625 |
0.00159 |
0.003140 |
0.00936 |
| 3.8 |
6330 |
0.00538 |
0.00148 |
0.002480 |
0.00829 |
| 3.9 |
7960 |
0.00550 |
0.00152 |
0.002520 |
0.00847 |
| 4.0 |
10000 |
0.00474 |
0.00143 |
0.001940 |
0.00754 |
| 4.1 |
12600 |
0.00433 |
0.00141 |
0.001560 |
0.00710 |
| 4.2 |
15900 |
0.00379 |
0.00136 |
0.001130 |
0.00646 |
| 4.3 |
20000 |
0.00311 |
0.00125 |
0.000656 |
0.00557 |
| 4.4 |
25200 |
0.00261 |
0.00113 |
0.000395 |
0.00482 |
| 4.5 |
31700 |
0.00284 |
0.00129 |
0.000307 |
0.00537 |
| 4.6 |
39900 |
0.00207 |
0.00113 |
-0.000153 |
0.00429 |
| 4.7 |
50300 |
0.00224 |
0.00132 |
-0.000335 |
0.00482 |
Monotone

| 2.4 |
252 |
0.0000 |
0.00916 |
0.00139 |
6.43e-03 |
0.01190 |
| 2.5 |
317 |
0.0038 |
0.00916 |
0.00192 |
5.40e-03 |
0.01290 |
| 2.6 |
399 |
0.0038 |
0.00916 |
0.00192 |
5.40e-03 |
0.01290 |
| 2.7 |
503 |
0.0038 |
0.00916 |
0.00192 |
5.40e-03 |
0.01290 |
| 2.8 |
633 |
0.0038 |
0.00916 |
0.00192 |
5.40e-03 |
0.01290 |
| 2.9 |
796 |
0.0038 |
0.00916 |
0.00192 |
5.40e-03 |
0.01290 |
| 3.0 |
1000 |
0.0038 |
0.00916 |
0.00192 |
5.40e-03 |
0.01290 |
| 3.1 |
1260 |
0.0370 |
0.00888 |
0.00190 |
5.16e-03 |
0.01260 |
| 3.2 |
1590 |
0.0703 |
0.00855 |
0.00189 |
4.85e-03 |
0.01230 |
| 3.3 |
2000 |
0.0894 |
0.00835 |
0.00186 |
4.70e-03 |
0.01200 |
| 3.4 |
2520 |
0.0929 |
0.00806 |
0.00182 |
4.49e-03 |
0.01160 |
| 3.5 |
3170 |
0.0959 |
0.00752 |
0.00175 |
4.09e-03 |
0.01100 |
| 3.6 |
3990 |
0.1240 |
0.00675 |
0.00166 |
3.50e-03 |
0.00999 |
| 3.7 |
5030 |
0.1500 |
0.00625 |
0.00159 |
3.14e-03 |
0.00936 |
| 3.8 |
6330 |
0.2100 |
0.00544 |
0.00148 |
2.54e-03 |
0.00834 |
| 3.9 |
7960 |
0.2320 |
0.00544 |
0.00152 |
2.46e-03 |
0.00842 |
| 4.0 |
10000 |
0.2910 |
0.00474 |
0.00143 |
1.94e-03 |
0.00754 |
| 4.1 |
12600 |
0.3360 |
0.00433 |
0.00141 |
1.56e-03 |
0.00710 |
| 4.2 |
15900 |
0.3780 |
0.00379 |
0.00136 |
1.13e-03 |
0.00646 |
| 4.3 |
20000 |
0.4400 |
0.00311 |
0.00125 |
6.56e-04 |
0.00557 |
| 4.4 |
25200 |
0.4620 |
0.00272 |
0.00113 |
5.09e-04 |
0.00494 |
| 4.5 |
31700 |
0.5190 |
0.00272 |
0.00129 |
1.92e-04 |
0.00525 |
| 4.6 |
39900 |
0.5750 |
0.00216 |
0.00113 |
-6.42e-05 |
0.00437 |
| 4.7 |
50300 |
0.6200 |
0.00216 |
0.00132 |
-4.23e-04 |
0.00473 |
Vaccine (change)
Unscaled (not monotone)

| -1.2800 |
0.0526 |
0.00584 |
0.00131 |
0.003280 |
0.00841 |
| -1.1800 |
0.0663 |
0.00590 |
0.00132 |
0.003310 |
0.00849 |
| -1.0800 |
0.0834 |
0.00590 |
0.00132 |
0.003310 |
0.00849 |
| -0.9790 |
0.1050 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.8790 |
0.1320 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.7790 |
0.1660 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.6790 |
0.2100 |
0.00596 |
0.00134 |
0.003320 |
0.00859 |
| -0.5790 |
0.2640 |
0.00603 |
0.00138 |
0.003330 |
0.00874 |
| -0.4790 |
0.3320 |
0.00603 |
0.00138 |
0.003330 |
0.00874 |
| -0.3790 |
0.4180 |
0.00603 |
0.00138 |
0.003330 |
0.00874 |
| -0.2790 |
0.5260 |
0.00606 |
0.00137 |
0.003380 |
0.00875 |
| -0.1790 |
0.6630 |
0.00612 |
0.00139 |
0.003400 |
0.00883 |
| -0.0787 |
0.8340 |
0.00615 |
0.00139 |
0.003430 |
0.00888 |
| 0.0213 |
1.0500 |
0.00596 |
0.00137 |
0.003270 |
0.00865 |
| 0.1210 |
1.3200 |
0.00604 |
0.00139 |
0.003310 |
0.00876 |
| 0.2210 |
1.6600 |
0.00589 |
0.00139 |
0.003170 |
0.00862 |
| 0.3210 |
2.1000 |
0.00600 |
0.00142 |
0.003210 |
0.00879 |
| 0.4210 |
2.6400 |
0.00611 |
0.00145 |
0.003260 |
0.00896 |
| 0.5210 |
3.3200 |
0.00636 |
0.00153 |
0.003360 |
0.00936 |
| 0.6210 |
4.1800 |
0.00648 |
0.00165 |
0.003250 |
0.00971 |
| 0.7210 |
5.2600 |
0.00728 |
0.00199 |
0.003380 |
0.01120 |
| 0.8210 |
6.6300 |
0.00761 |
0.00214 |
0.003420 |
0.01180 |
| 0.9210 |
8.3400 |
0.00780 |
0.00215 |
0.003590 |
0.01200 |
| 1.0200 |
10.5000 |
0.00795 |
0.00216 |
0.003720 |
0.01220 |
| 1.1200 |
13.2000 |
0.00833 |
0.00231 |
0.003800 |
0.01290 |
| 1.2200 |
16.6000 |
0.00754 |
0.00226 |
0.003110 |
0.01200 |
| 1.3200 |
21.0000 |
0.00768 |
0.00246 |
0.002860 |
0.01250 |
| 1.4200 |
26.4000 |
0.00703 |
0.00255 |
0.002040 |
0.01200 |
| 1.5200 |
33.2000 |
0.00597 |
0.00233 |
0.001400 |
0.01050 |
| 1.6200 |
41.8000 |
0.00581 |
0.00249 |
0.000936 |
0.01070 |
| 1.7200 |
52.6000 |
0.00548 |
0.00255 |
0.000486 |
0.01050 |
| 1.8200 |
66.3000 |
0.00929 |
0.00532 |
-0.001130 |
0.01970 |
| 1.9200 |
83.4000 |
0.01270 |
0.00665 |
-0.000338 |
0.02570 |
| 2.0200 |
105.0000 |
0.00972 |
0.00531 |
-0.000684 |
0.02010 |
| 2.1200 |
132.0000 |
0.01760 |
0.00983 |
-0.001670 |
0.03690 |
| 2.2200 |
166.0000 |
0.01780 |
0.01060 |
-0.002910 |
0.03850 |
Unscaled (monotone)

| -1.2800 |
0.0526 |
0.00000 |
0.00643 |
0.00131 |
0.00387 |
0.00900 |
| -1.1800 |
0.0663 |
0.00583 |
0.00643 |
0.00132 |
0.00384 |
0.00903 |
| -1.0800 |
0.0834 |
0.00583 |
0.00643 |
0.00132 |
0.00384 |
0.00903 |
| -0.9790 |
0.1050 |
0.00692 |
0.00643 |
0.00133 |
0.00383 |
0.00904 |
| -0.8790 |
0.1320 |
0.00692 |
0.00643 |
0.00133 |
0.00383 |
0.00904 |
| -0.7790 |
0.1660 |
0.00692 |
0.00643 |
0.00133 |
0.00383 |
0.00904 |
| -0.6790 |
0.2100 |
0.01280 |
0.00643 |
0.00134 |
0.00380 |
0.00907 |
| -0.5790 |
0.2640 |
0.01970 |
0.00643 |
0.00138 |
0.00373 |
0.00914 |
| -0.4790 |
0.3320 |
0.01970 |
0.00643 |
0.00138 |
0.00373 |
0.00914 |
| -0.3790 |
0.4180 |
0.01970 |
0.00643 |
0.00138 |
0.00373 |
0.00914 |
| -0.2790 |
0.5260 |
0.02920 |
0.00643 |
0.00137 |
0.00375 |
0.00912 |
| -0.1790 |
0.6630 |
0.04050 |
0.00643 |
0.00139 |
0.00372 |
0.00915 |
| -0.0787 |
0.8340 |
0.05590 |
0.00643 |
0.00139 |
0.00371 |
0.00916 |
| 0.0213 |
1.0500 |
0.07420 |
0.00643 |
0.00137 |
0.00375 |
0.00912 |
| 0.1210 |
1.3200 |
0.09240 |
0.00643 |
0.00139 |
0.00371 |
0.00916 |
| 0.2210 |
1.6600 |
0.11300 |
0.00643 |
0.00139 |
0.00371 |
0.00916 |
| 0.3210 |
2.1000 |
0.13200 |
0.00643 |
0.00142 |
0.00365 |
0.00922 |
| 0.4210 |
2.6400 |
0.14900 |
0.00643 |
0.00145 |
0.00358 |
0.00928 |
| 0.5210 |
3.3200 |
0.18500 |
0.00643 |
0.00153 |
0.00343 |
0.00944 |
| 0.6210 |
4.1800 |
0.23100 |
0.00643 |
0.00165 |
0.00321 |
0.00966 |
| 0.7210 |
5.2600 |
0.29000 |
0.00643 |
0.00199 |
0.00254 |
0.01030 |
| 0.8210 |
6.6300 |
0.31700 |
0.00643 |
0.00214 |
0.00224 |
0.01060 |
| 0.9210 |
8.3400 |
0.34900 |
0.00643 |
0.00215 |
0.00222 |
0.01060 |
| 1.0200 |
10.5000 |
0.37700 |
0.00643 |
0.00216 |
0.00220 |
0.01070 |
| 1.1200 |
13.2000 |
0.39400 |
0.00643 |
0.00231 |
0.00191 |
0.01100 |
| 1.2200 |
16.6000 |
0.44300 |
0.00643 |
0.00226 |
0.00200 |
0.01090 |
| 1.3200 |
21.0000 |
0.49900 |
0.00643 |
0.00246 |
0.00161 |
0.01130 |
| 1.4200 |
26.4000 |
0.59000 |
0.00643 |
0.00255 |
0.00144 |
0.01140 |
| 1.5200 |
33.2000 |
0.60800 |
0.00643 |
0.00233 |
0.00186 |
0.01100 |
| 1.6200 |
41.8000 |
0.65800 |
0.00643 |
0.00249 |
0.00156 |
0.01130 |
| 1.7200 |
52.6000 |
0.70100 |
0.00643 |
0.00255 |
0.00144 |
0.01140 |
| 1.8200 |
66.3000 |
0.77200 |
0.00643 |
0.00532 |
-0.00398 |
0.01690 |
| 1.9200 |
83.4000 |
0.81900 |
0.00643 |
0.00665 |
-0.00660 |
0.01950 |
| 2.0200 |
105.0000 |
0.86600 |
0.00643 |
0.00531 |
-0.00397 |
0.01680 |
| 2.1200 |
132.0000 |
0.91300 |
0.00643 |
0.00983 |
-0.01280 |
0.02570 |
| 2.2200 |
166.0000 |
0.92400 |
0.00643 |
0.01060 |
-0.01430 |
0.02710 |
VE scale (1 minus risk / placebo risk) (monotone)

| -1.2800 |
0.0526 |
0.286 |
0.178 |
-0.0627 |
0.636 |
| -1.1800 |
0.0663 |
0.286 |
0.180 |
-0.0666 |
0.640 |
| -1.0800 |
0.0834 |
0.286 |
0.180 |
-0.0666 |
0.640 |
| -0.9790 |
0.1050 |
0.286 |
0.181 |
-0.0685 |
0.641 |
| -0.8790 |
0.1320 |
0.286 |
0.181 |
-0.0685 |
0.641 |
| -0.7790 |
0.1660 |
0.286 |
0.181 |
-0.0685 |
0.641 |
| -0.6790 |
0.2100 |
0.286 |
0.183 |
-0.0721 |
0.645 |
| -0.5790 |
0.2640 |
0.286 |
0.188 |
-0.0815 |
0.654 |
| -0.4790 |
0.3320 |
0.286 |
0.188 |
-0.0815 |
0.654 |
| -0.3790 |
0.4180 |
0.286 |
0.188 |
-0.0815 |
0.654 |
| -0.2790 |
0.5260 |
0.286 |
0.187 |
-0.0793 |
0.652 |
| -0.1790 |
0.6630 |
0.286 |
0.189 |
-0.0835 |
0.656 |
| -0.0787 |
0.8340 |
0.286 |
0.190 |
-0.0852 |
0.658 |
| 0.0213 |
1.0500 |
0.286 |
0.187 |
-0.0798 |
0.653 |
| 0.1210 |
1.3200 |
0.286 |
0.189 |
-0.0848 |
0.658 |
| 0.2210 |
1.6600 |
0.286 |
0.189 |
-0.0848 |
0.658 |
| 0.3210 |
2.1000 |
0.286 |
0.194 |
-0.0933 |
0.666 |
| 0.4210 |
2.6400 |
0.286 |
0.198 |
-0.1020 |
0.675 |
| 0.5210 |
3.3200 |
0.286 |
0.209 |
-0.1220 |
0.695 |
| 0.6210 |
4.1800 |
0.286 |
0.224 |
-0.1530 |
0.726 |
| 0.7210 |
5.2600 |
0.286 |
0.271 |
-0.2450 |
0.817 |
| 0.8210 |
6.6300 |
0.286 |
0.292 |
-0.2850 |
0.858 |
| 0.9210 |
8.3400 |
0.286 |
0.293 |
-0.2880 |
0.861 |
| 1.0200 |
10.5000 |
0.286 |
0.294 |
-0.2900 |
0.863 |
| 1.1200 |
13.2000 |
0.286 |
0.315 |
-0.3310 |
0.903 |
| 1.2200 |
16.6000 |
0.286 |
0.308 |
-0.3170 |
0.890 |
| 1.3200 |
21.0000 |
0.286 |
0.335 |
-0.3700 |
0.943 |
| 1.4200 |
26.4000 |
0.286 |
0.347 |
-0.3940 |
0.967 |
| 1.5200 |
33.2000 |
0.286 |
0.318 |
-0.3360 |
0.909 |
| 1.6200 |
41.8000 |
0.286 |
0.339 |
-0.3780 |
0.951 |
| 1.7200 |
52.6000 |
0.286 |
0.347 |
-0.3950 |
0.967 |
| 1.8200 |
66.3000 |
0.286 |
0.724 |
-1.1300 |
1.710 |
| 1.9200 |
83.4000 |
0.286 |
0.906 |
-1.4900 |
2.060 |
| 2.0200 |
105.0000 |
0.286 |
0.723 |
-1.1300 |
1.700 |
| 2.1200 |
132.0000 |
0.286 |
1.340 |
-2.3400 |
2.910 |
| 2.2200 |
166.0000 |
0.286 |
1.440 |
-2.5300 |
3.110 |
IgG Spike Omicron
Vaccine
Unscaled (not monotone)

| 2.4 |
252 |
0.00522 |
0.00105 |
3.17e-03 |
0.00727 |
| 2.5 |
317 |
0.00594 |
0.00134 |
3.32e-03 |
0.00855 |
| 2.6 |
399 |
0.00594 |
0.00134 |
3.32e-03 |
0.00855 |
| 2.7 |
503 |
0.00594 |
0.00134 |
3.32e-03 |
0.00855 |
| 2.8 |
633 |
0.00594 |
0.00134 |
3.32e-03 |
0.00855 |
| 2.9 |
796 |
0.00594 |
0.00134 |
3.32e-03 |
0.00855 |
| 3.0 |
1000 |
0.00594 |
0.00134 |
3.32e-03 |
0.00855 |
| 3.1 |
1260 |
0.00594 |
0.00134 |
3.32e-03 |
0.00855 |
| 3.2 |
1590 |
0.00599 |
0.00136 |
3.33e-03 |
0.00865 |
| 3.3 |
2000 |
0.00599 |
0.00136 |
3.33e-03 |
0.00866 |
| 3.4 |
2520 |
0.00600 |
0.00136 |
3.34e-03 |
0.00867 |
| 3.5 |
3170 |
0.00608 |
0.00138 |
3.37e-03 |
0.00878 |
| 3.6 |
3990 |
0.00614 |
0.00141 |
3.38e-03 |
0.00890 |
| 3.7 |
5030 |
0.00626 |
0.00145 |
3.42e-03 |
0.00911 |
| 3.8 |
6330 |
0.00630 |
0.00145 |
3.46e-03 |
0.00914 |
| 3.9 |
7960 |
0.00631 |
0.00143 |
3.51e-03 |
0.00911 |
| 4.0 |
10000 |
0.00633 |
0.00143 |
3.53e-03 |
0.00914 |
| 4.1 |
12600 |
0.00642 |
0.00145 |
3.58e-03 |
0.00926 |
| 4.2 |
15900 |
0.00626 |
0.00144 |
3.44e-03 |
0.00908 |
| 4.3 |
20000 |
0.00659 |
0.00153 |
3.60e-03 |
0.00958 |
| 4.4 |
25200 |
0.00681 |
0.00159 |
3.69e-03 |
0.00993 |
| 4.5 |
31700 |
0.00702 |
0.00165 |
3.78e-03 |
0.01030 |
| 4.6 |
39900 |
0.00719 |
0.00171 |
3.85e-03 |
0.01050 |
| 4.7 |
50300 |
0.00686 |
0.00170 |
3.52e-03 |
0.01020 |
| 4.8 |
63300 |
0.00726 |
0.00206 |
3.22e-03 |
0.01130 |
| 4.9 |
79600 |
0.00723 |
0.00221 |
2.90e-03 |
0.01160 |
| 5.0 |
100000 |
0.00674 |
0.00230 |
2.23e-03 |
0.01120 |
| 5.1 |
126000 |
0.00565 |
0.00287 |
2.06e-05 |
0.01130 |
| 5.2 |
159000 |
0.00238 |
0.00146 |
-4.89e-04 |
0.00524 |
| 5.3 |
200000 |
0.00371 |
0.00236 |
-9.22e-04 |
0.00834 |
Unscaled (monotone)

| 2.4 |
252 |
0.0000 |
0.00628 |
0.00105 |
4.23e-03 |
0.00833 |
| 2.5 |
317 |
0.0117 |
0.00628 |
0.00134 |
3.66e-03 |
0.00890 |
| 2.6 |
399 |
0.0117 |
0.00628 |
0.00134 |
3.66e-03 |
0.00890 |
| 2.7 |
503 |
0.0117 |
0.00628 |
0.00134 |
3.66e-03 |
0.00890 |
| 2.8 |
633 |
0.0117 |
0.00628 |
0.00134 |
3.66e-03 |
0.00890 |
| 2.9 |
796 |
0.0117 |
0.00628 |
0.00134 |
3.66e-03 |
0.00890 |
| 3.0 |
1000 |
0.0117 |
0.00628 |
0.00134 |
3.66e-03 |
0.00890 |
| 3.1 |
1260 |
0.0117 |
0.00628 |
0.00134 |
3.66e-03 |
0.00890 |
| 3.2 |
1590 |
0.0180 |
0.00628 |
0.00136 |
3.62e-03 |
0.00894 |
| 3.3 |
2000 |
0.0186 |
0.00628 |
0.00136 |
3.62e-03 |
0.00894 |
| 3.4 |
2520 |
0.0196 |
0.00628 |
0.00136 |
3.61e-03 |
0.00895 |
| 3.5 |
3170 |
0.0313 |
0.00628 |
0.00138 |
3.57e-03 |
0.00899 |
| 3.6 |
3990 |
0.0377 |
0.00628 |
0.00141 |
3.52e-03 |
0.00904 |
| 3.7 |
5030 |
0.0515 |
0.00628 |
0.00145 |
3.43e-03 |
0.00913 |
| 3.8 |
6330 |
0.0643 |
0.00628 |
0.00145 |
3.44e-03 |
0.00912 |
| 3.9 |
7960 |
0.0738 |
0.00628 |
0.00143 |
3.48e-03 |
0.00908 |
| 4.0 |
10000 |
0.0802 |
0.00628 |
0.00143 |
3.47e-03 |
0.00909 |
| 4.1 |
12600 |
0.1050 |
0.00628 |
0.00145 |
3.44e-03 |
0.00912 |
| 4.2 |
15900 |
0.1250 |
0.00628 |
0.00144 |
3.46e-03 |
0.00910 |
| 4.3 |
20000 |
0.1560 |
0.00628 |
0.00153 |
3.29e-03 |
0.00927 |
| 4.4 |
25200 |
0.1810 |
0.00628 |
0.00159 |
3.16e-03 |
0.00940 |
| 4.5 |
31700 |
0.2120 |
0.00628 |
0.00165 |
3.04e-03 |
0.00951 |
| 4.6 |
39900 |
0.2330 |
0.00628 |
0.00171 |
2.94e-03 |
0.00962 |
| 4.7 |
50300 |
0.2690 |
0.00628 |
0.00170 |
2.94e-03 |
0.00962 |
| 4.8 |
63300 |
0.4170 |
0.00628 |
0.00206 |
2.24e-03 |
0.01030 |
| 4.9 |
79600 |
0.5180 |
0.00628 |
0.00221 |
1.95e-03 |
0.01060 |
| 5.0 |
100000 |
0.6330 |
0.00628 |
0.00230 |
1.77e-03 |
0.01080 |
| 5.1 |
126000 |
0.7360 |
0.00565 |
0.00287 |
2.05e-05 |
0.01130 |
| 5.2 |
159000 |
0.7830 |
0.00304 |
0.00146 |
1.78e-04 |
0.00591 |
| 5.3 |
200000 |
0.8750 |
0.00304 |
0.00236 |
-1.59e-03 |
0.00768 |
VE scale (1 minus risk / placebo risk) (monotone)

| 2.4 |
252 |
0.304 |
0.158 |
-0.00633 |
0.614 |
| 2.5 |
317 |
0.304 |
0.183 |
-0.05510 |
0.662 |
| 2.6 |
399 |
0.304 |
0.183 |
-0.05510 |
0.662 |
| 2.7 |
503 |
0.304 |
0.183 |
-0.05510 |
0.662 |
| 2.8 |
633 |
0.304 |
0.183 |
-0.05510 |
0.662 |
| 2.9 |
796 |
0.304 |
0.183 |
-0.05510 |
0.662 |
| 3.0 |
1000 |
0.304 |
0.183 |
-0.05510 |
0.662 |
| 3.1 |
1260 |
0.304 |
0.183 |
-0.05510 |
0.662 |
| 3.2 |
1590 |
0.304 |
0.185 |
-0.05860 |
0.666 |
| 3.3 |
2000 |
0.304 |
0.185 |
-0.05900 |
0.666 |
| 3.4 |
2520 |
0.304 |
0.185 |
-0.05950 |
0.667 |
| 3.5 |
3170 |
0.304 |
0.187 |
-0.06310 |
0.670 |
| 3.6 |
3990 |
0.304 |
0.190 |
-0.06780 |
0.675 |
| 3.7 |
5030 |
0.304 |
0.194 |
-0.07590 |
0.683 |
| 3.8 |
6330 |
0.304 |
0.193 |
-0.07530 |
0.683 |
| 3.9 |
7960 |
0.304 |
0.192 |
-0.07170 |
0.679 |
| 4.0 |
10000 |
0.304 |
0.192 |
-0.07220 |
0.679 |
| 4.1 |
12600 |
0.304 |
0.193 |
-0.07530 |
0.683 |
| 4.2 |
15900 |
0.304 |
0.192 |
-0.07340 |
0.681 |
| 4.3 |
20000 |
0.304 |
0.200 |
-0.08930 |
0.697 |
| 4.4 |
25200 |
0.304 |
0.207 |
-0.10200 |
0.709 |
| 4.5 |
31700 |
0.304 |
0.212 |
-0.11200 |
0.720 |
| 4.6 |
39900 |
0.304 |
0.218 |
-0.12300 |
0.730 |
| 4.7 |
50300 |
0.304 |
0.217 |
-0.12200 |
0.729 |
| 4.8 |
63300 |
0.304 |
0.253 |
-0.19200 |
0.799 |
| 4.9 |
79600 |
0.304 |
0.268 |
-0.22100 |
0.828 |
| 5.0 |
100000 |
0.304 |
0.277 |
-0.23900 |
0.846 |
| 5.1 |
126000 |
0.373 |
0.333 |
-0.28000 |
1.030 |
| 5.2 |
159000 |
0.662 |
0.170 |
0.32800 |
0.996 |
| 5.3 |
200000 |
0.662 |
0.267 |
0.13800 |
1.190 |
Placebo
Not monotone

| 2.4 |
252 |
0.00902 |
0.001390 |
0.006290 |
0.01170 |
| 2.5 |
317 |
0.00852 |
0.001870 |
0.004850 |
0.01220 |
| 2.6 |
399 |
0.00852 |
0.001870 |
0.004850 |
0.01220 |
| 2.7 |
503 |
0.00852 |
0.001870 |
0.004850 |
0.01220 |
| 2.8 |
633 |
0.00852 |
0.001870 |
0.004850 |
0.01220 |
| 2.9 |
796 |
0.00822 |
0.001850 |
0.004590 |
0.01180 |
| 3.0 |
1000 |
0.00834 |
0.001920 |
0.004570 |
0.01210 |
| 3.1 |
1260 |
0.00802 |
0.001880 |
0.004340 |
0.01170 |
| 3.2 |
1590 |
0.00747 |
0.001800 |
0.003930 |
0.01100 |
| 3.3 |
2000 |
0.00700 |
0.001750 |
0.003570 |
0.01040 |
| 3.4 |
2520 |
0.00624 |
0.001700 |
0.002900 |
0.00958 |
| 3.5 |
3170 |
0.00573 |
0.001680 |
0.002450 |
0.00901 |
| 3.6 |
3990 |
0.00356 |
0.001300 |
0.001010 |
0.00612 |
| 3.7 |
5030 |
0.00335 |
0.001310 |
0.000788 |
0.00591 |
| 3.8 |
6330 |
0.00250 |
0.001110 |
0.000321 |
0.00468 |
| 3.9 |
7960 |
0.00174 |
0.000965 |
-0.000153 |
0.00363 |
| 4.0 |
10000 |
0.00188 |
0.001090 |
-0.000257 |
0.00402 |
| 4.1 |
12600 |
0.00196 |
0.001200 |
-0.000403 |
0.00432 |
| 4.2 |
15900 |
0.00216 |
0.001280 |
-0.000345 |
0.00465 |
| 4.3 |
20000 |
0.00215 |
0.001440 |
-0.000664 |
0.00496 |
Monotone

| 2.4 |
252 |
0.0000 |
0.00902 |
0.001390 |
6.29e-03 |
0.01170 |
| 2.5 |
317 |
0.0648 |
0.00852 |
0.001870 |
4.85e-03 |
0.01220 |
| 2.6 |
399 |
0.0648 |
0.00852 |
0.001870 |
4.85e-03 |
0.01220 |
| 2.7 |
503 |
0.0648 |
0.00852 |
0.001870 |
4.85e-03 |
0.01220 |
| 2.8 |
633 |
0.0648 |
0.00852 |
0.001870 |
4.85e-03 |
0.01220 |
| 2.9 |
796 |
0.1150 |
0.00828 |
0.001850 |
4.65e-03 |
0.01190 |
| 3.0 |
1000 |
0.1530 |
0.00828 |
0.001920 |
4.51e-03 |
0.01200 |
| 3.1 |
1260 |
0.1550 |
0.00802 |
0.001880 |
4.34e-03 |
0.01170 |
| 3.2 |
1590 |
0.1610 |
0.00747 |
0.001800 |
3.93e-03 |
0.01100 |
| 3.3 |
2000 |
0.1970 |
0.00700 |
0.001750 |
3.57e-03 |
0.01040 |
| 3.4 |
2520 |
0.2490 |
0.00624 |
0.001700 |
2.90e-03 |
0.00958 |
| 3.5 |
3170 |
0.2730 |
0.00573 |
0.001680 |
2.45e-03 |
0.00901 |
| 3.6 |
3990 |
0.3160 |
0.00356 |
0.001300 |
1.01e-03 |
0.00612 |
| 3.7 |
5030 |
0.3780 |
0.00335 |
0.001310 |
7.88e-04 |
0.00591 |
| 3.8 |
6330 |
0.3870 |
0.00250 |
0.001110 |
3.21e-04 |
0.00468 |
| 3.9 |
7960 |
0.4380 |
0.00198 |
0.000965 |
8.49e-05 |
0.00387 |
| 4.0 |
10000 |
0.4970 |
0.00198 |
0.001090 |
-1.64e-04 |
0.00412 |
| 4.1 |
12600 |
0.5260 |
0.00198 |
0.001200 |
-3.83e-04 |
0.00434 |
| 4.2 |
15900 |
0.6340 |
0.00198 |
0.001280 |
-5.23e-04 |
0.00448 |
| 4.3 |
20000 |
0.7060 |
0.00198 |
0.001440 |
-8.36e-04 |
0.00479 |
Vaccine (change)
Unscaled (not monotone)

| -1.3200 |
0.0476 |
0.00584 |
0.00131 |
0.003280 |
0.00841 |
| -1.2200 |
0.0599 |
0.00590 |
0.00132 |
0.003310 |
0.00849 |
| -1.1200 |
0.0754 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -1.0200 |
0.0950 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.9220 |
0.1200 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.8220 |
0.1510 |
0.00592 |
0.00133 |
0.003310 |
0.00852 |
| -0.7220 |
0.1890 |
0.00598 |
0.00135 |
0.003320 |
0.00863 |
| -0.6220 |
0.2390 |
0.00603 |
0.00138 |
0.003330 |
0.00874 |
| -0.5220 |
0.3000 |
0.00603 |
0.00138 |
0.003330 |
0.00874 |
| -0.4220 |
0.3780 |
0.00606 |
0.00137 |
0.003380 |
0.00875 |
| -0.3220 |
0.4760 |
0.00606 |
0.00137 |
0.003380 |
0.00875 |
| -0.2220 |
0.5990 |
0.00612 |
0.00139 |
0.003400 |
0.00883 |
| -0.1220 |
0.7540 |
0.00614 |
0.00139 |
0.003420 |
0.00886 |
| -0.0224 |
0.9500 |
0.00616 |
0.00139 |
0.003430 |
0.00888 |
| 0.0776 |
1.2000 |
0.00600 |
0.00138 |
0.003280 |
0.00871 |
| 0.1780 |
1.5100 |
0.00575 |
0.00135 |
0.003100 |
0.00839 |
| 0.2780 |
1.8900 |
0.00597 |
0.00142 |
0.003180 |
0.00877 |
| 0.3780 |
2.3900 |
0.00600 |
0.00142 |
0.003200 |
0.00879 |
| 0.4780 |
3.0000 |
0.00578 |
0.00140 |
0.003030 |
0.00854 |
| 0.5780 |
3.7800 |
0.00603 |
0.00149 |
0.003120 |
0.00894 |
| 0.6780 |
4.7600 |
0.00612 |
0.00150 |
0.003170 |
0.00906 |
| 0.7780 |
5.9900 |
0.00589 |
0.00156 |
0.002840 |
0.00894 |
| 0.8780 |
7.5400 |
0.00666 |
0.00177 |
0.003200 |
0.01010 |
| 0.9780 |
9.5000 |
0.00692 |
0.00188 |
0.003230 |
0.01060 |
| 1.0800 |
12.0000 |
0.00682 |
0.00194 |
0.003030 |
0.01060 |
| 1.1800 |
15.1000 |
0.00710 |
0.00207 |
0.003060 |
0.01120 |
| 1.2800 |
18.9000 |
0.00731 |
0.00218 |
0.003040 |
0.01160 |
| 1.3800 |
23.9000 |
0.00768 |
0.00229 |
0.003190 |
0.01220 |
| 1.4800 |
30.0000 |
0.00775 |
0.00240 |
0.003040 |
0.01250 |
| 1.5800 |
37.8000 |
0.00687 |
0.00238 |
0.002210 |
0.01150 |
| 1.6800 |
47.6000 |
0.00681 |
0.00249 |
0.001940 |
0.01170 |
| 1.7800 |
59.9000 |
0.00550 |
0.00227 |
0.001060 |
0.00995 |
| 1.8800 |
75.4000 |
0.00599 |
0.00265 |
0.000796 |
0.01120 |
| 1.9800 |
95.0000 |
0.00743 |
0.00414 |
-0.000677 |
0.01550 |
| 2.0800 |
120.0000 |
0.00981 |
0.00632 |
-0.002570 |
0.02220 |
| 2.1800 |
151.0000 |
0.00817 |
0.00651 |
-0.004590 |
0.02090 |
| 2.2800 |
189.0000 |
0.00948 |
0.00641 |
-0.003090 |
0.02200 |
| 2.3800 |
239.0000 |
0.01280 |
0.01350 |
-0.013700 |
0.03930 |
| 2.4800 |
300.0000 |
0.01110 |
0.01690 |
-0.021900 |
0.04420 |
Unscaled (monotone)

| -1.3200 |
0.0476 |
0.00000 |
0.00626 |
0.00131 |
0.00370 |
0.00882 |
| -1.2200 |
0.0599 |
0.00583 |
0.00626 |
0.00132 |
0.00367 |
0.00885 |
| -1.1200 |
0.0754 |
0.00692 |
0.00626 |
0.00133 |
0.00365 |
0.00887 |
| -1.0200 |
0.0950 |
0.00692 |
0.00626 |
0.00133 |
0.00365 |
0.00887 |
| -0.9220 |
0.1200 |
0.00692 |
0.00626 |
0.00133 |
0.00365 |
0.00887 |
| -0.8220 |
0.1510 |
0.00692 |
0.00626 |
0.00133 |
0.00365 |
0.00887 |
| -0.7220 |
0.1890 |
0.01280 |
0.00626 |
0.00135 |
0.00360 |
0.00892 |
| -0.6220 |
0.2390 |
0.01970 |
0.00626 |
0.00138 |
0.00356 |
0.00896 |
| -0.5220 |
0.3000 |
0.01970 |
0.00626 |
0.00138 |
0.00356 |
0.00896 |
| -0.4220 |
0.3780 |
0.02920 |
0.00626 |
0.00137 |
0.00358 |
0.00894 |
| -0.3220 |
0.4760 |
0.02920 |
0.00626 |
0.00137 |
0.00358 |
0.00894 |
| -0.2220 |
0.5990 |
0.04000 |
0.00626 |
0.00139 |
0.00354 |
0.00898 |
| -0.1220 |
0.7540 |
0.05120 |
0.00626 |
0.00139 |
0.00354 |
0.00898 |
| -0.0224 |
0.9500 |
0.05700 |
0.00626 |
0.00139 |
0.00353 |
0.00899 |
| 0.0776 |
1.2000 |
0.08080 |
0.00626 |
0.00138 |
0.00355 |
0.00897 |
| 0.1780 |
1.5100 |
0.08160 |
0.00626 |
0.00135 |
0.00361 |
0.00891 |
| 0.2780 |
1.8900 |
0.11800 |
0.00626 |
0.00142 |
0.00347 |
0.00905 |
| 0.3780 |
2.3900 |
0.12500 |
0.00626 |
0.00142 |
0.00347 |
0.00905 |
| 0.4780 |
3.0000 |
0.13800 |
0.00626 |
0.00140 |
0.00351 |
0.00901 |
| 0.5780 |
3.7800 |
0.16900 |
0.00626 |
0.00149 |
0.00335 |
0.00917 |
| 0.6780 |
4.7600 |
0.19300 |
0.00626 |
0.00150 |
0.00332 |
0.00920 |
| 0.7780 |
5.9900 |
0.23800 |
0.00626 |
0.00156 |
0.00321 |
0.00931 |
| 0.8780 |
7.5400 |
0.28400 |
0.00626 |
0.00177 |
0.00280 |
0.00972 |
| 0.9780 |
9.5000 |
0.30300 |
0.00626 |
0.00188 |
0.00257 |
0.00995 |
| 1.0800 |
12.0000 |
0.32200 |
0.00626 |
0.00194 |
0.00246 |
0.01010 |
| 1.1800 |
15.1000 |
0.34900 |
0.00626 |
0.00207 |
0.00221 |
0.01030 |
| 1.2800 |
18.9000 |
0.36500 |
0.00626 |
0.00218 |
0.00198 |
0.01050 |
| 1.3800 |
23.9000 |
0.40900 |
0.00626 |
0.00229 |
0.00177 |
0.01070 |
| 1.4800 |
30.0000 |
0.47600 |
0.00626 |
0.00240 |
0.00155 |
0.01100 |
| 1.5800 |
37.8000 |
0.56500 |
0.00626 |
0.00238 |
0.00160 |
0.01090 |
| 1.6800 |
47.6000 |
0.60600 |
0.00626 |
0.00249 |
0.00139 |
0.01110 |
| 1.7800 |
59.9000 |
0.64400 |
0.00626 |
0.00227 |
0.00182 |
0.01070 |
| 1.8800 |
75.4000 |
0.71000 |
0.00626 |
0.00265 |
0.00107 |
0.01150 |
| 1.9800 |
95.0000 |
0.77000 |
0.00626 |
0.00414 |
-0.00185 |
0.01440 |
| 2.0800 |
120.0000 |
0.81400 |
0.00626 |
0.00632 |
-0.00612 |
0.01860 |
| 2.1800 |
151.0000 |
0.83000 |
0.00626 |
0.00651 |
-0.00650 |
0.01900 |
| 2.2800 |
189.0000 |
0.85800 |
0.00626 |
0.00641 |
-0.00631 |
0.01880 |
| 2.3800 |
239.0000 |
0.90300 |
0.00626 |
0.01350 |
-0.02020 |
0.03280 |
| 2.4800 |
300.0000 |
0.92100 |
0.00626 |
0.01690 |
-0.02680 |
0.03930 |
VE scale (1 minus risk / placebo risk) (monotone)

| -1.3200 |
0.0476 |
0.306 |
0.177 |
-0.0403 |
0.652 |
| -1.2200 |
0.0599 |
0.306 |
0.179 |
-0.0441 |
0.656 |
| -1.1200 |
0.0754 |
0.306 |
0.179 |
-0.0460 |
0.657 |
| -1.0200 |
0.0950 |
0.306 |
0.179 |
-0.0460 |
0.657 |
| -0.9220 |
0.1200 |
0.306 |
0.179 |
-0.0460 |
0.657 |
| -0.8220 |
0.1510 |
0.306 |
0.179 |
-0.0460 |
0.657 |
| -0.7220 |
0.1890 |
0.306 |
0.183 |
-0.0528 |
0.664 |
| -0.6220 |
0.2390 |
0.306 |
0.186 |
-0.0589 |
0.670 |
| -0.5220 |
0.3000 |
0.306 |
0.186 |
-0.0589 |
0.670 |
| -0.4220 |
0.3780 |
0.306 |
0.185 |
-0.0567 |
0.668 |
| -0.3220 |
0.4760 |
0.306 |
0.185 |
-0.0567 |
0.668 |
| -0.2220 |
0.5990 |
0.306 |
0.187 |
-0.0609 |
0.672 |
| -0.1220 |
0.7540 |
0.306 |
0.188 |
-0.0619 |
0.673 |
| -0.0224 |
0.9500 |
0.306 |
0.188 |
-0.0625 |
0.674 |
| 0.0776 |
1.2000 |
0.306 |
0.187 |
-0.0603 |
0.672 |
| 0.1780 |
1.5100 |
0.306 |
0.182 |
-0.0520 |
0.663 |
| 0.2780 |
1.8900 |
0.306 |
0.192 |
-0.0713 |
0.683 |
| 0.3780 |
2.3900 |
0.306 |
0.192 |
-0.0711 |
0.683 |
| 0.4780 |
3.0000 |
0.306 |
0.190 |
-0.0660 |
0.677 |
| 0.5780 |
3.7800 |
0.306 |
0.201 |
-0.0877 |
0.699 |
| 0.6780 |
4.7600 |
0.306 |
0.203 |
-0.0917 |
0.703 |
| 0.7780 |
5.9900 |
0.306 |
0.210 |
-0.1060 |
0.717 |
| 0.8780 |
7.5400 |
0.306 |
0.238 |
-0.1620 |
0.773 |
| 0.9780 |
9.5000 |
0.306 |
0.254 |
-0.1920 |
0.804 |
| 1.0800 |
12.0000 |
0.306 |
0.261 |
-0.2070 |
0.818 |
| 1.1800 |
15.1000 |
0.306 |
0.279 |
-0.2410 |
0.852 |
| 1.2800 |
18.9000 |
0.306 |
0.295 |
-0.2720 |
0.883 |
| 1.3800 |
23.9000 |
0.306 |
0.309 |
-0.3000 |
0.911 |
| 1.4800 |
30.0000 |
0.306 |
0.325 |
-0.3310 |
0.942 |
| 1.5800 |
37.8000 |
0.306 |
0.321 |
-0.3240 |
0.935 |
| 1.6800 |
47.6000 |
0.306 |
0.336 |
-0.3520 |
0.964 |
| 1.7800 |
59.9000 |
0.306 |
0.306 |
-0.2940 |
0.906 |
| 1.8800 |
75.4000 |
0.306 |
0.358 |
-0.3950 |
1.010 |
| 1.9800 |
95.0000 |
0.306 |
0.559 |
-0.7890 |
1.400 |
| 2.0800 |
120.0000 |
0.306 |
0.853 |
-1.3700 |
1.980 |
| 2.1800 |
151.0000 |
0.306 |
0.879 |
-1.4200 |
2.030 |
| 2.2800 |
189.0000 |
0.306 |
0.866 |
-1.3900 |
2.000 |
| 2.3800 |
239.0000 |
0.306 |
1.830 |
-3.2700 |
3.880 |
| 2.4800 |
300.0000 |
0.306 |
2.280 |
-4.1500 |
4.760 |
IgG Spike Cross-Reactivity Score
Vaccine
Unscaled (not monotone)

| 3.06 |
1150 |
0.00522 |
0.00105 |
0.003170 |
0.00727 |
| 3.16 |
1450 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.26 |
1830 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.36 |
2300 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.46 |
2900 |
0.00594 |
0.00134 |
0.003320 |
0.00855 |
| 3.56 |
3650 |
0.00599 |
0.00136 |
0.003330 |
0.00865 |
| 3.66 |
4590 |
0.00599 |
0.00136 |
0.003330 |
0.00865 |
| 3.76 |
5780 |
0.00599 |
0.00136 |
0.003330 |
0.00866 |
| 3.86 |
7280 |
0.00600 |
0.00136 |
0.003330 |
0.00866 |
| 3.96 |
9160 |
0.00608 |
0.00138 |
0.003370 |
0.00878 |
| 4.06 |
11500 |
0.00608 |
0.00138 |
0.003370 |
0.00878 |
| 4.16 |
14500 |
0.00613 |
0.00139 |
0.003400 |
0.00887 |
| 4.26 |
18300 |
0.00626 |
0.00145 |
0.003420 |
0.00910 |
| 4.36 |
23000 |
0.00631 |
0.00143 |
0.003510 |
0.00910 |
| 4.46 |
29000 |
0.00634 |
0.00143 |
0.003530 |
0.00914 |
| 4.56 |
36500 |
0.00634 |
0.00143 |
0.003530 |
0.00914 |
| 4.66 |
45900 |
0.00648 |
0.00146 |
0.003610 |
0.00934 |
| 4.76 |
57800 |
0.00676 |
0.00154 |
0.003740 |
0.00977 |
| 4.86 |
72800 |
0.00686 |
0.00161 |
0.003710 |
0.01000 |
| 4.96 |
91600 |
0.00704 |
0.00166 |
0.003790 |
0.01030 |
| 5.06 |
115000 |
0.00685 |
0.00172 |
0.003480 |
0.01020 |
| 5.16 |
145000 |
0.00663 |
0.00176 |
0.003180 |
0.01010 |
| 5.26 |
183000 |
0.00604 |
0.00198 |
0.002170 |
0.00992 |
| 5.36 |
230000 |
0.00572 |
0.00198 |
0.001830 |
0.00960 |
| 5.46 |
290000 |
0.00550 |
0.00243 |
0.000743 |
0.01020 |
| 5.56 |
365000 |
0.00262 |
0.00142 |
-0.000159 |
0.00539 |
Unscaled (monotone)

| 3.06 |
1150 |
0.0000 |
0.00621 |
0.00105 |
0.004160 |
0.00826 |
| 3.16 |
1450 |
0.0117 |
0.00621 |
0.00134 |
0.003600 |
0.00883 |
| 3.26 |
1830 |
0.0117 |
0.00621 |
0.00134 |
0.003600 |
0.00883 |
| 3.36 |
2300 |
0.0117 |
0.00621 |
0.00134 |
0.003600 |
0.00883 |
| 3.46 |
2900 |
0.0117 |
0.00621 |
0.00134 |
0.003600 |
0.00883 |
| 3.56 |
3650 |
0.0175 |
0.00621 |
0.00136 |
0.003550 |
0.00887 |
| 3.66 |
4590 |
0.0175 |
0.00621 |
0.00136 |
0.003550 |
0.00887 |
| 3.76 |
5780 |
0.0180 |
0.00621 |
0.00136 |
0.003550 |
0.00888 |
| 3.86 |
7280 |
0.0186 |
0.00621 |
0.00136 |
0.003550 |
0.00888 |
| 3.96 |
9160 |
0.0313 |
0.00621 |
0.00138 |
0.003510 |
0.00892 |
| 4.06 |
11500 |
0.0313 |
0.00621 |
0.00138 |
0.003510 |
0.00892 |
| 4.16 |
14500 |
0.0393 |
0.00621 |
0.00139 |
0.003480 |
0.00895 |
| 4.26 |
18300 |
0.0521 |
0.00621 |
0.00145 |
0.003370 |
0.00905 |
| 4.36 |
23000 |
0.0733 |
0.00621 |
0.00143 |
0.003420 |
0.00901 |
| 4.46 |
29000 |
0.0813 |
0.00621 |
0.00143 |
0.003410 |
0.00902 |
| 4.56 |
36500 |
0.0813 |
0.00621 |
0.00143 |
0.003410 |
0.00902 |
| 4.66 |
45900 |
0.1150 |
0.00621 |
0.00146 |
0.003350 |
0.00908 |
| 4.76 |
57800 |
0.1590 |
0.00621 |
0.00154 |
0.003200 |
0.00923 |
| 4.86 |
72800 |
0.1840 |
0.00621 |
0.00161 |
0.003060 |
0.00937 |
| 4.96 |
91600 |
0.2150 |
0.00621 |
0.00166 |
0.002970 |
0.00946 |
| 5.06 |
115000 |
0.2570 |
0.00621 |
0.00172 |
0.002840 |
0.00959 |
| 5.16 |
145000 |
0.3240 |
0.00621 |
0.00176 |
0.002760 |
0.00967 |
| 5.26 |
183000 |
0.4690 |
0.00604 |
0.00198 |
0.002170 |
0.00992 |
| 5.36 |
230000 |
0.6100 |
0.00572 |
0.00198 |
0.001830 |
0.00960 |
| 5.46 |
290000 |
0.7100 |
0.00550 |
0.00243 |
0.000743 |
0.01020 |
| 5.56 |
365000 |
0.7920 |
0.00262 |
0.00142 |
-0.000159 |
0.00539 |
VE scale (1 minus risk / placebo risk) (monotone)

| 3.06 |
1150 |
0.311 |
0.157 |
0.00252 |
0.619 |
| 3.16 |
1450 |
0.311 |
0.182 |
-0.04640 |
0.668 |
| 3.26 |
1830 |
0.311 |
0.182 |
-0.04640 |
0.668 |
| 3.36 |
2300 |
0.311 |
0.182 |
-0.04640 |
0.668 |
| 3.46 |
2900 |
0.311 |
0.182 |
-0.04640 |
0.668 |
| 3.56 |
3650 |
0.311 |
0.184 |
-0.05010 |
0.672 |
| 3.66 |
4590 |
0.311 |
0.184 |
-0.05010 |
0.672 |
| 3.76 |
5780 |
0.311 |
0.184 |
-0.05050 |
0.672 |
| 3.86 |
7280 |
0.311 |
0.185 |
-0.05090 |
0.673 |
| 3.96 |
9160 |
0.311 |
0.186 |
-0.05450 |
0.676 |
| 4.06 |
11500 |
0.311 |
0.186 |
-0.05450 |
0.676 |
| 4.16 |
14500 |
0.311 |
0.188 |
-0.05690 |
0.679 |
| 4.26 |
18300 |
0.311 |
0.193 |
-0.06690 |
0.689 |
| 4.36 |
23000 |
0.311 |
0.191 |
-0.06270 |
0.685 |
| 4.46 |
29000 |
0.311 |
0.191 |
-0.06370 |
0.686 |
| 4.56 |
36500 |
0.311 |
0.191 |
-0.06370 |
0.686 |
| 4.66 |
45900 |
0.311 |
0.194 |
-0.06900 |
0.691 |
| 4.76 |
57800 |
0.311 |
0.201 |
-0.08300 |
0.705 |
| 4.86 |
72800 |
0.311 |
0.208 |
-0.09630 |
0.718 |
| 4.96 |
91600 |
0.311 |
0.212 |
-0.10500 |
0.727 |
| 5.06 |
115000 |
0.311 |
0.218 |
-0.11700 |
0.739 |
| 5.16 |
145000 |
0.311 |
0.223 |
-0.12500 |
0.747 |
| 5.26 |
183000 |
0.330 |
0.242 |
-0.14500 |
0.805 |
| 5.36 |
230000 |
0.366 |
0.240 |
-0.10500 |
0.837 |
| 5.46 |
290000 |
0.391 |
0.285 |
-0.16800 |
0.949 |
| 5.56 |
365000 |
0.710 |
0.163 |
0.39000 |
1.030 |
Placebo
Not monotone

| 2.4 |
252 |
0.00902 |
0.00139 |
6.29e-03 |
0.01170 |
| 2.5 |
317 |
0.00917 |
0.00191 |
5.42e-03 |
0.01290 |
| 2.6 |
399 |
0.00917 |
0.00191 |
5.42e-03 |
0.01290 |
| 2.7 |
503 |
0.00919 |
0.00192 |
5.43e-03 |
0.01300 |
| 2.8 |
633 |
0.00927 |
0.00193 |
5.48e-03 |
0.01300 |
| 2.9 |
796 |
0.00932 |
0.00194 |
5.51e-03 |
0.01310 |
| 3.0 |
1000 |
0.00932 |
0.00194 |
5.51e-03 |
0.01310 |
| 3.1 |
1260 |
0.00853 |
0.00184 |
4.92e-03 |
0.01210 |
| 3.2 |
1590 |
0.00848 |
0.00186 |
4.83e-03 |
0.01210 |
| 3.3 |
2000 |
0.00865 |
0.00190 |
4.92e-03 |
0.01240 |
| 3.4 |
2520 |
0.00821 |
0.00186 |
4.57e-03 |
0.01190 |
| 3.5 |
3170 |
0.00741 |
0.00175 |
3.98e-03 |
0.01080 |
| 3.6 |
3990 |
0.00741 |
0.00179 |
3.91e-03 |
0.01090 |
| 3.7 |
5030 |
0.00665 |
0.00169 |
3.34e-03 |
0.00997 |
| 3.8 |
6330 |
0.00586 |
0.00159 |
2.74e-03 |
0.00898 |
| 3.9 |
7960 |
0.00540 |
0.00157 |
2.33e-03 |
0.00847 |
| 4.0 |
10000 |
0.00429 |
0.00146 |
1.42e-03 |
0.00716 |
| 4.1 |
12600 |
0.00305 |
0.00122 |
6.53e-04 |
0.00545 |
| 4.2 |
15900 |
0.00314 |
0.00127 |
6.55e-04 |
0.00562 |
| 4.3 |
20000 |
0.00258 |
0.00111 |
3.99e-04 |
0.00476 |
| 4.4 |
25200 |
0.00233 |
0.00111 |
1.51e-04 |
0.00452 |
| 4.5 |
31700 |
0.00251 |
0.00125 |
7.08e-05 |
0.00496 |
| 4.6 |
39900 |
0.00206 |
0.00116 |
-2.25e-04 |
0.00434 |
| 4.7 |
50300 |
0.00173 |
0.00120 |
-6.19e-04 |
0.00408 |
Monotone

| 2.4 |
252 |
0.00000 |
0.00921 |
0.00139 |
6.48e-03 |
0.01190 |
| 2.5 |
317 |
0.00279 |
0.00921 |
0.00191 |
5.46e-03 |
0.01300 |
| 2.6 |
399 |
0.00279 |
0.00921 |
0.00191 |
5.46e-03 |
0.01300 |
| 2.7 |
503 |
0.00430 |
0.00921 |
0.00192 |
5.45e-03 |
0.01300 |
| 2.8 |
633 |
0.01760 |
0.00921 |
0.00193 |
5.43e-03 |
0.01300 |
| 2.9 |
796 |
0.02160 |
0.00921 |
0.00194 |
5.40e-03 |
0.01300 |
| 3.0 |
1000 |
0.02210 |
0.00921 |
0.00194 |
5.40e-03 |
0.01300 |
| 3.1 |
1260 |
0.02850 |
0.00855 |
0.00184 |
4.95e-03 |
0.01220 |
| 3.2 |
1590 |
0.06190 |
0.00855 |
0.00186 |
4.90e-03 |
0.01220 |
| 3.3 |
2000 |
0.09140 |
0.00855 |
0.00190 |
4.82e-03 |
0.01230 |
| 3.4 |
2520 |
0.11700 |
0.00821 |
0.00186 |
4.57e-03 |
0.01190 |
| 3.5 |
3170 |
0.14500 |
0.00741 |
0.00175 |
3.98e-03 |
0.01080 |
| 3.6 |
3990 |
0.16300 |
0.00741 |
0.00179 |
3.91e-03 |
0.01090 |
| 3.7 |
5030 |
0.20800 |
0.00665 |
0.00169 |
3.34e-03 |
0.00997 |
| 3.8 |
6330 |
0.21900 |
0.00586 |
0.00159 |
2.74e-03 |
0.00898 |
| 3.9 |
7960 |
0.25500 |
0.00540 |
0.00157 |
2.33e-03 |
0.00847 |
| 4.0 |
10000 |
0.30600 |
0.00429 |
0.00146 |
1.42e-03 |
0.00716 |
| 4.1 |
12600 |
0.43100 |
0.00309 |
0.00122 |
6.96e-04 |
0.00549 |
| 4.2 |
15900 |
0.44500 |
0.00309 |
0.00127 |
6.11e-04 |
0.00558 |
| 4.3 |
20000 |
0.47600 |
0.00258 |
0.00111 |
3.99e-04 |
0.00476 |
| 4.4 |
25200 |
0.52300 |
0.00242 |
0.00111 |
2.41e-04 |
0.00461 |
| 4.5 |
31700 |
0.57000 |
0.00242 |
0.00125 |
-1.99e-05 |
0.00487 |
| 4.6 |
39900 |
0.61700 |
0.00206 |
0.00116 |
-2.25e-04 |
0.00434 |
| 4.7 |
50300 |
0.66400 |
0.00173 |
0.00120 |
-6.19e-04 |
0.00408 |
Vaccine (change)
Unscaled (not monotone)

| -1.1400 |
0.0727 |
0.00584 |
0.00131 |
3.28e-03 |
0.00841 |
| -1.0400 |
0.0915 |
0.00592 |
0.00133 |
3.31e-03 |
0.00852 |
| -0.9380 |
0.1150 |
0.00592 |
0.00133 |
3.31e-03 |
0.00852 |
| -0.8380 |
0.1450 |
0.00592 |
0.00133 |
3.31e-03 |
0.00852 |
| -0.7380 |
0.1830 |
0.00592 |
0.00133 |
3.31e-03 |
0.00852 |
| -0.6380 |
0.2300 |
0.00599 |
0.00136 |
3.32e-03 |
0.00866 |
| -0.5380 |
0.2890 |
0.00603 |
0.00138 |
3.33e-03 |
0.00874 |
| -0.4380 |
0.3640 |
0.00603 |
0.00138 |
3.33e-03 |
0.00874 |
| -0.3380 |
0.4590 |
0.00606 |
0.00137 |
3.38e-03 |
0.00875 |
| -0.2380 |
0.5780 |
0.00606 |
0.00137 |
3.38e-03 |
0.00875 |
| -0.1380 |
0.7270 |
0.00613 |
0.00139 |
3.42e-03 |
0.00885 |
| -0.0384 |
0.9150 |
0.00618 |
0.00140 |
3.44e-03 |
0.00891 |
| 0.0616 |
1.1500 |
0.00599 |
0.00138 |
3.28e-03 |
0.00870 |
| 0.1620 |
1.4500 |
0.00579 |
0.00136 |
3.13e-03 |
0.00845 |
| 0.2620 |
1.8300 |
0.00582 |
0.00137 |
3.14e-03 |
0.00850 |
| 0.3620 |
2.3000 |
0.00600 |
0.00142 |
3.21e-03 |
0.00879 |
| 0.4620 |
2.8900 |
0.00607 |
0.00145 |
3.23e-03 |
0.00890 |
| 0.5620 |
3.6400 |
0.00617 |
0.00152 |
3.20e-03 |
0.00915 |
| 0.6620 |
4.5900 |
0.00606 |
0.00155 |
3.03e-03 |
0.00909 |
| 0.7620 |
5.7800 |
0.00728 |
0.00197 |
3.42e-03 |
0.01110 |
| 0.8620 |
7.2700 |
0.00740 |
0.00198 |
3.51e-03 |
0.01130 |
| 0.9620 |
9.1500 |
0.00771 |
0.00211 |
3.58e-03 |
0.01180 |
| 1.0600 |
11.5000 |
0.00785 |
0.00218 |
3.57e-03 |
0.01210 |
| 1.1600 |
14.5000 |
0.00845 |
0.00240 |
3.75e-03 |
0.01320 |
| 1.2600 |
18.3000 |
0.00783 |
0.00239 |
3.14e-03 |
0.01250 |
| 1.3600 |
23.0000 |
0.00738 |
0.00223 |
3.02e-03 |
0.01180 |
| 1.4600 |
28.9000 |
0.00632 |
0.00229 |
1.82e-03 |
0.01080 |
| 1.5600 |
36.4000 |
0.00596 |
0.00232 |
1.42e-03 |
0.01050 |
| 1.6600 |
45.9000 |
0.00565 |
0.00241 |
9.31e-04 |
0.01040 |
| 1.7600 |
57.8000 |
0.00680 |
0.00330 |
3.27e-04 |
0.01330 |
| 1.8600 |
72.7000 |
0.00508 |
0.00320 |
-1.20e-03 |
0.01140 |
| 1.9600 |
91.5000 |
0.00660 |
0.00331 |
9.96e-05 |
0.01310 |
Unscaled (monotone)

| -1.1400 |
0.0727 |
0.00000 |
0.00640 |
0.00131 |
0.003840 |
0.00896 |
| -1.0400 |
0.0915 |
0.00692 |
0.00640 |
0.00133 |
0.003790 |
0.00900 |
| -0.9380 |
0.1150 |
0.00692 |
0.00640 |
0.00133 |
0.003790 |
0.00900 |
| -0.8380 |
0.1450 |
0.00692 |
0.00640 |
0.00133 |
0.003790 |
0.00900 |
| -0.7380 |
0.1830 |
0.00692 |
0.00640 |
0.00133 |
0.003790 |
0.00900 |
| -0.6380 |
0.2300 |
0.01380 |
0.00640 |
0.00136 |
0.003730 |
0.00907 |
| -0.5380 |
0.2890 |
0.01970 |
0.00640 |
0.00138 |
0.003700 |
0.00910 |
| -0.4380 |
0.3640 |
0.01970 |
0.00640 |
0.00138 |
0.003700 |
0.00910 |
| -0.3380 |
0.4590 |
0.02920 |
0.00640 |
0.00137 |
0.003710 |
0.00908 |
| -0.2380 |
0.5780 |
0.02920 |
0.00640 |
0.00137 |
0.003710 |
0.00908 |
| -0.1380 |
0.7270 |
0.04690 |
0.00640 |
0.00139 |
0.003680 |
0.00911 |
| -0.0384 |
0.9150 |
0.06230 |
0.00640 |
0.00140 |
0.003660 |
0.00914 |
| 0.0616 |
1.1500 |
0.08050 |
0.00640 |
0.00138 |
0.003690 |
0.00911 |
| 0.1620 |
1.4500 |
0.09320 |
0.00640 |
0.00136 |
0.003740 |
0.00906 |
| 0.2620 |
1.8300 |
0.10100 |
0.00640 |
0.00137 |
0.003720 |
0.00908 |
| 0.3620 |
2.3000 |
0.13200 |
0.00640 |
0.00142 |
0.003610 |
0.00919 |
| 0.4620 |
2.8900 |
0.14000 |
0.00640 |
0.00145 |
0.003560 |
0.00923 |
| 0.5620 |
3.6400 |
0.20100 |
0.00640 |
0.00152 |
0.003420 |
0.00937 |
| 0.6620 |
4.5900 |
0.22000 |
0.00640 |
0.00155 |
0.003370 |
0.00943 |
| 0.7620 |
5.7800 |
0.29600 |
0.00640 |
0.00197 |
0.002540 |
0.01030 |
| 0.8620 |
7.2700 |
0.31300 |
0.00640 |
0.00198 |
0.002520 |
0.01030 |
| 0.9620 |
9.1500 |
0.34100 |
0.00640 |
0.00211 |
0.002270 |
0.01050 |
| 1.0600 |
11.5000 |
0.34800 |
0.00640 |
0.00218 |
0.002120 |
0.01070 |
| 1.1600 |
14.5000 |
0.38500 |
0.00640 |
0.00240 |
0.001690 |
0.01110 |
| 1.2600 |
18.3000 |
0.42600 |
0.00640 |
0.00239 |
0.001700 |
0.01110 |
| 1.3600 |
23.0000 |
0.47100 |
0.00640 |
0.00223 |
0.002030 |
0.01080 |
| 1.4600 |
28.9000 |
0.56700 |
0.00632 |
0.00229 |
0.001820 |
0.01080 |
| 1.5600 |
36.4000 |
0.61600 |
0.00614 |
0.00232 |
0.001600 |
0.01070 |
| 1.6600 |
45.9000 |
0.64500 |
0.00614 |
0.00241 |
0.001420 |
0.01090 |
| 1.7600 |
57.8000 |
0.69100 |
0.00614 |
0.00330 |
-0.000334 |
0.01260 |
| 1.8600 |
72.7000 |
0.75100 |
0.00584 |
0.00320 |
-0.000442 |
0.01210 |
| 1.9600 |
91.5000 |
0.80000 |
0.00584 |
0.00331 |
-0.000658 |
0.01230 |
VE scale (1 minus risk / placebo risk) (monotone)

| -1.1400 |
0.0727 |
0.290 |
0.178 |
-0.0581 |
0.639 |
| -1.0400 |
0.0915 |
0.290 |
0.181 |
-0.0639 |
0.645 |
| -0.9380 |
0.1150 |
0.290 |
0.181 |
-0.0639 |
0.645 |
| -0.8380 |
0.1450 |
0.290 |
0.181 |
-0.0639 |
0.645 |
| -0.7380 |
0.1830 |
0.290 |
0.181 |
-0.0639 |
0.645 |
| -0.6380 |
0.2300 |
0.290 |
0.185 |
-0.0728 |
0.654 |
| -0.5380 |
0.2890 |
0.290 |
0.187 |
-0.0769 |
0.658 |
| -0.4380 |
0.3640 |
0.290 |
0.187 |
-0.0769 |
0.658 |
| -0.3380 |
0.4590 |
0.290 |
0.186 |
-0.0746 |
0.655 |
| -0.2380 |
0.5780 |
0.290 |
0.186 |
-0.0746 |
0.655 |
| -0.1380 |
0.7270 |
0.290 |
0.188 |
-0.0789 |
0.660 |
| -0.0384 |
0.9150 |
0.290 |
0.190 |
-0.0818 |
0.663 |
| 0.0616 |
1.1500 |
0.290 |
0.188 |
-0.0777 |
0.659 |
| 0.1620 |
1.4500 |
0.290 |
0.185 |
-0.0714 |
0.652 |
| 0.2620 |
1.8300 |
0.290 |
0.186 |
-0.0738 |
0.655 |
| 0.3620 |
2.3000 |
0.290 |
0.194 |
-0.0889 |
0.670 |
| 0.4620 |
2.8900 |
0.290 |
0.197 |
-0.0952 |
0.676 |
| 0.5620 |
3.6400 |
0.290 |
0.206 |
-0.1140 |
0.695 |
| 0.6620 |
4.5900 |
0.290 |
0.210 |
-0.1220 |
0.702 |
| 0.7620 |
5.7800 |
0.290 |
0.268 |
-0.2340 |
0.815 |
| 0.8620 |
7.2700 |
0.290 |
0.269 |
-0.2380 |
0.818 |
| 0.9620 |
9.1500 |
0.290 |
0.287 |
-0.2710 |
0.852 |
| 1.0600 |
11.5000 |
0.290 |
0.297 |
-0.2920 |
0.873 |
| 1.1600 |
14.5000 |
0.290 |
0.326 |
-0.3490 |
0.930 |
| 1.2600 |
18.3000 |
0.290 |
0.326 |
-0.3480 |
0.929 |
| 1.3600 |
23.0000 |
0.290 |
0.303 |
-0.3030 |
0.884 |
| 1.4600 |
28.9000 |
0.300 |
0.310 |
-0.3080 |
0.908 |
| 1.5600 |
36.4000 |
0.320 |
0.311 |
-0.2890 |
0.929 |
| 1.6600 |
45.9000 |
0.320 |
0.323 |
-0.3130 |
0.952 |
| 1.7600 |
57.8000 |
0.320 |
0.443 |
-0.5480 |
1.190 |
| 1.8600 |
72.7000 |
0.352 |
0.423 |
-0.4770 |
1.180 |
| 1.9600 |
91.5000 |
0.352 |
0.438 |
-0.5060 |
1.210 |
nAb ID50 Reference
Vaccine
Unscaled (not monotone)

| 1.3 |
20.0 |
0.00522 |
0.00105 |
0.003170 |
0.00727 |
| 1.4 |
25.2 |
0.00596 |
0.00132 |
0.003370 |
0.00854 |
| 1.5 |
31.7 |
0.00596 |
0.00132 |
0.003370 |
0.00854 |
| 1.6 |
39.9 |
0.00596 |
0.00132 |
0.003370 |
0.00854 |
| 1.7 |
50.2 |
0.00596 |
0.00132 |
0.003370 |
0.00854 |
| 1.8 |
63.2 |
0.00596 |
0.00132 |
0.003370 |
0.00854 |
| 1.9 |
79.6 |
0.00596 |
0.00132 |
0.003370 |
0.00854 |
| 2.0 |
100.0 |
0.00596 |
0.00132 |
0.003370 |
0.00855 |
| 2.1 |
126.0 |
0.00602 |
0.00133 |
0.003410 |
0.00863 |
| 2.2 |
159.0 |
0.00610 |
0.00136 |
0.003430 |
0.00877 |
| 2.3 |
200.0 |
0.00609 |
0.00134 |
0.003460 |
0.00872 |
| 2.4 |
252.0 |
0.00609 |
0.00134 |
0.003470 |
0.00871 |
| 2.5 |
317.0 |
0.00610 |
0.00134 |
0.003480 |
0.00871 |
| 2.6 |
399.0 |
0.00584 |
0.00130 |
0.003290 |
0.00840 |
| 2.7 |
502.0 |
0.00562 |
0.00128 |
0.003110 |
0.00814 |
| 2.8 |
632.0 |
0.00572 |
0.00131 |
0.003150 |
0.00829 |
| 2.9 |
796.0 |
0.00577 |
0.00133 |
0.003170 |
0.00838 |
| 3.0 |
1000.0 |
0.00557 |
0.00131 |
0.003010 |
0.00813 |
| 3.1 |
1260.0 |
0.00561 |
0.00132 |
0.003020 |
0.00819 |
| 3.2 |
1590.0 |
0.00570 |
0.00135 |
0.003050 |
0.00834 |
| 3.3 |
2000.0 |
0.00575 |
0.00136 |
0.003080 |
0.00842 |
| 3.4 |
2520.0 |
0.00590 |
0.00141 |
0.003140 |
0.00866 |
| 3.5 |
3170.0 |
0.00570 |
0.00138 |
0.003010 |
0.00840 |
| 3.6 |
3990.0 |
0.00574 |
0.00142 |
0.002950 |
0.00853 |
| 3.7 |
5020.0 |
0.00606 |
0.00153 |
0.003080 |
0.00905 |
| 3.8 |
6320.0 |
0.00607 |
0.00157 |
0.002990 |
0.00914 |
| 3.9 |
7960.0 |
0.00460 |
0.00137 |
0.001910 |
0.00730 |
| 4.0 |
10000.0 |
0.00402 |
0.00138 |
0.001310 |
0.00673 |
| 4.1 |
12600.0 |
0.00359 |
0.00134 |
0.000961 |
0.00622 |
| 4.2 |
15900.0 |
0.00357 |
0.00142 |
0.000793 |
0.00634 |
| 4.3 |
20000.0 |
0.00376 |
0.00183 |
0.000171 |
0.00735 |
Unscaled (monotone)

| 1.3 |
20.0 |
0.0000 |
0.00595 |
0.00105 |
3.90e-03 |
0.00800 |
| 1.4 |
25.2 |
0.0122 |
0.00595 |
0.00132 |
3.36e-03 |
0.00853 |
| 1.5 |
31.7 |
0.0122 |
0.00595 |
0.00132 |
3.36e-03 |
0.00853 |
| 1.6 |
39.9 |
0.0122 |
0.00595 |
0.00132 |
3.36e-03 |
0.00853 |
| 1.7 |
50.2 |
0.0122 |
0.00595 |
0.00132 |
3.36e-03 |
0.00853 |
| 1.8 |
63.2 |
0.0122 |
0.00595 |
0.00132 |
3.36e-03 |
0.00853 |
| 1.9 |
79.6 |
0.0122 |
0.00595 |
0.00132 |
3.36e-03 |
0.00853 |
| 2.0 |
100.0 |
0.0127 |
0.00595 |
0.00132 |
3.36e-03 |
0.00853 |
| 2.1 |
126.0 |
0.0221 |
0.00595 |
0.00133 |
3.34e-03 |
0.00855 |
| 2.2 |
159.0 |
0.0297 |
0.00595 |
0.00136 |
3.28e-03 |
0.00862 |
| 2.3 |
200.0 |
0.0336 |
0.00595 |
0.00134 |
3.31e-03 |
0.00858 |
| 2.4 |
252.0 |
0.0366 |
0.00595 |
0.00134 |
3.33e-03 |
0.00857 |
| 2.5 |
317.0 |
0.0396 |
0.00595 |
0.00134 |
3.33e-03 |
0.00856 |
| 2.6 |
399.0 |
0.0398 |
0.00584 |
0.00130 |
3.29e-03 |
0.00840 |
| 2.7 |
502.0 |
0.0431 |
0.00576 |
0.00128 |
3.25e-03 |
0.00828 |
| 2.8 |
632.0 |
0.0534 |
0.00576 |
0.00131 |
3.19e-03 |
0.00833 |
| 2.9 |
796.0 |
0.0634 |
0.00576 |
0.00133 |
3.15e-03 |
0.00837 |
| 3.0 |
1000.0 |
0.0750 |
0.00576 |
0.00131 |
3.20e-03 |
0.00832 |
| 3.1 |
1260.0 |
0.0784 |
0.00576 |
0.00132 |
3.17e-03 |
0.00835 |
| 3.2 |
1590.0 |
0.0921 |
0.00576 |
0.00135 |
3.12e-03 |
0.00841 |
| 3.3 |
2000.0 |
0.1010 |
0.00576 |
0.00136 |
3.09e-03 |
0.00843 |
| 3.4 |
2520.0 |
0.1240 |
0.00576 |
0.00141 |
3.00e-03 |
0.00852 |
| 3.5 |
3170.0 |
0.1590 |
0.00576 |
0.00138 |
3.07e-03 |
0.00846 |
| 3.6 |
3990.0 |
0.1880 |
0.00576 |
0.00142 |
2.97e-03 |
0.00855 |
| 3.7 |
5020.0 |
0.2290 |
0.00576 |
0.00153 |
2.77e-03 |
0.00875 |
| 3.8 |
6320.0 |
0.2670 |
0.00576 |
0.00157 |
2.68e-03 |
0.00884 |
| 3.9 |
7960.0 |
0.3050 |
0.00460 |
0.00137 |
1.91e-03 |
0.00730 |
| 4.0 |
10000.0 |
0.3750 |
0.00402 |
0.00138 |
1.31e-03 |
0.00673 |
| 4.1 |
12600.0 |
0.4860 |
0.00364 |
0.00134 |
1.01e-03 |
0.00627 |
| 4.2 |
15900.0 |
0.5560 |
0.00364 |
0.00142 |
8.64e-04 |
0.00641 |
| 4.3 |
20000.0 |
0.6910 |
0.00364 |
0.00183 |
5.05e-05 |
0.00723 |
VE scale (1 minus risk / placebo risk) (monotone)

| 1.3 |
20.0 |
0.341 |
0.139 |
0.06830 |
0.613 |
| 1.4 |
25.2 |
0.341 |
0.175 |
-0.00241 |
0.684 |
| 1.5 |
31.7 |
0.341 |
0.175 |
-0.00241 |
0.684 |
| 1.6 |
39.9 |
0.341 |
0.175 |
-0.00241 |
0.684 |
| 1.7 |
50.2 |
0.341 |
0.175 |
-0.00241 |
0.684 |
| 1.8 |
63.2 |
0.341 |
0.175 |
-0.00241 |
0.684 |
| 1.9 |
79.6 |
0.341 |
0.175 |
-0.00241 |
0.684 |
| 2.0 |
100.0 |
0.341 |
0.175 |
-0.00284 |
0.684 |
| 2.1 |
126.0 |
0.341 |
0.177 |
-0.00586 |
0.687 |
| 2.2 |
159.0 |
0.341 |
0.181 |
-0.01400 |
0.695 |
| 2.3 |
200.0 |
0.341 |
0.178 |
-0.00899 |
0.690 |
| 2.4 |
252.0 |
0.341 |
0.178 |
-0.00731 |
0.689 |
| 2.5 |
317.0 |
0.341 |
0.177 |
-0.00711 |
0.688 |
| 2.6 |
399.0 |
0.352 |
0.172 |
0.01450 |
0.690 |
| 2.7 |
502.0 |
0.361 |
0.169 |
0.03020 |
0.692 |
| 2.8 |
632.0 |
0.361 |
0.173 |
0.02240 |
0.700 |
| 2.9 |
796.0 |
0.361 |
0.175 |
0.01820 |
0.704 |
| 3.0 |
1000.0 |
0.361 |
0.172 |
0.02400 |
0.698 |
| 3.1 |
1260.0 |
0.361 |
0.174 |
0.02070 |
0.702 |
| 3.2 |
1590.0 |
0.361 |
0.178 |
0.01310 |
0.709 |
| 3.3 |
2000.0 |
0.361 |
0.179 |
0.00943 |
0.713 |
| 3.4 |
2520.0 |
0.361 |
0.185 |
-0.00228 |
0.725 |
| 3.5 |
3170.0 |
0.361 |
0.181 |
0.00637 |
0.716 |
| 3.6 |
3990.0 |
0.361 |
0.187 |
-0.00590 |
0.728 |
| 3.7 |
5020.0 |
0.361 |
0.201 |
-0.03230 |
0.755 |
| 3.8 |
6320.0 |
0.361 |
0.207 |
-0.04410 |
0.766 |
| 3.9 |
7960.0 |
0.490 |
0.171 |
0.15400 |
0.825 |
| 4.0 |
10000.0 |
0.554 |
0.168 |
0.22600 |
0.883 |
| 4.1 |
12600.0 |
0.597 |
0.160 |
0.28200 |
0.911 |
| 4.2 |
15900.0 |
0.597 |
0.169 |
0.26500 |
0.928 |
| 4.3 |
20000.0 |
0.597 |
0.219 |
0.16800 |
1.030 |
Placebo
Not monotone

| 1.3 |
20.0 |
0.00902 |
0.00139 |
0.006290 |
0.01170 |
| 1.4 |
25.2 |
0.00781 |
0.00176 |
0.004360 |
0.01130 |
| 1.5 |
31.7 |
0.00781 |
0.00176 |
0.004360 |
0.01130 |
| 1.6 |
39.9 |
0.00781 |
0.00176 |
0.004360 |
0.01130 |
| 1.7 |
50.2 |
0.00783 |
0.00176 |
0.004380 |
0.01130 |
| 1.8 |
63.2 |
0.00783 |
0.00176 |
0.004380 |
0.01130 |
| 1.9 |
79.6 |
0.00758 |
0.00173 |
0.004180 |
0.01100 |
| 2.0 |
100.0 |
0.00733 |
0.00171 |
0.003980 |
0.01070 |
| 2.1 |
126.0 |
0.00748 |
0.00174 |
0.004070 |
0.01090 |
| 2.2 |
159.0 |
0.00660 |
0.00163 |
0.003400 |
0.00980 |
| 2.3 |
200.0 |
0.00561 |
0.00150 |
0.002680 |
0.00854 |
| 2.4 |
252.0 |
0.00536 |
0.00152 |
0.002390 |
0.00833 |
| 2.5 |
317.0 |
0.00511 |
0.00150 |
0.002180 |
0.00804 |
| 2.6 |
399.0 |
0.00444 |
0.00140 |
0.001700 |
0.00719 |
| 2.7 |
502.0 |
0.00450 |
0.00142 |
0.001710 |
0.00728 |
| 2.8 |
632.0 |
0.00418 |
0.00139 |
0.001460 |
0.00691 |
| 2.9 |
796.0 |
0.00271 |
0.00116 |
0.000435 |
0.00498 |
| 3.0 |
1000.0 |
0.00218 |
0.00105 |
0.000110 |
0.00424 |
| 3.1 |
1260.0 |
0.00223 |
0.00108 |
0.000117 |
0.00435 |
| 3.2 |
1590.0 |
0.00245 |
0.00116 |
0.000164 |
0.00473 |
| 3.3 |
2000.0 |
0.00256 |
0.00122 |
0.000174 |
0.00494 |
| 3.4 |
2520.0 |
0.00211 |
0.00115 |
-0.000153 |
0.00437 |
Monotone

| 1.3 |
20.0 |
0.000 |
0.00902 |
0.00139 |
6.29e-03 |
0.01170 |
| 1.4 |
25.2 |
0.210 |
0.00782 |
0.00176 |
4.37e-03 |
0.01130 |
| 1.5 |
31.7 |
0.210 |
0.00782 |
0.00176 |
4.37e-03 |
0.01130 |
| 1.6 |
39.9 |
0.210 |
0.00782 |
0.00176 |
4.37e-03 |
0.01130 |
| 1.7 |
50.2 |
0.211 |
0.00782 |
0.00176 |
4.36e-03 |
0.01130 |
| 1.8 |
63.2 |
0.212 |
0.00782 |
0.00176 |
4.36e-03 |
0.01130 |
| 1.9 |
79.6 |
0.214 |
0.00758 |
0.00173 |
4.18e-03 |
0.01100 |
| 2.0 |
100.0 |
0.226 |
0.00741 |
0.00171 |
4.06e-03 |
0.01080 |
| 2.1 |
126.0 |
0.235 |
0.00741 |
0.00174 |
4.00e-03 |
0.01080 |
| 2.2 |
159.0 |
0.243 |
0.00660 |
0.00163 |
3.40e-03 |
0.00980 |
| 2.3 |
200.0 |
0.258 |
0.00561 |
0.00150 |
2.68e-03 |
0.00854 |
| 2.4 |
252.0 |
0.282 |
0.00536 |
0.00152 |
2.39e-03 |
0.00833 |
| 2.5 |
317.0 |
0.298 |
0.00511 |
0.00150 |
2.18e-03 |
0.00804 |
| 2.6 |
399.0 |
0.316 |
0.00447 |
0.00140 |
1.72e-03 |
0.00721 |
| 2.7 |
502.0 |
0.323 |
0.00447 |
0.00142 |
1.68e-03 |
0.00725 |
| 2.8 |
632.0 |
0.347 |
0.00418 |
0.00139 |
1.46e-03 |
0.00691 |
| 2.9 |
796.0 |
0.388 |
0.00271 |
0.00116 |
4.35e-04 |
0.00498 |
| 3.0 |
1000.0 |
0.438 |
0.00235 |
0.00105 |
2.87e-04 |
0.00442 |
| 3.1 |
1260.0 |
0.461 |
0.00235 |
0.00108 |
2.36e-04 |
0.00447 |
| 3.2 |
1590.0 |
0.528 |
0.00235 |
0.00116 |
7.28e-05 |
0.00463 |
| 3.3 |
2000.0 |
0.560 |
0.00235 |
0.00122 |
-3.14e-05 |
0.00474 |
| 3.4 |
2520.0 |
0.605 |
0.00211 |
0.00115 |
-1.53e-04 |
0.00437 |
Vaccine (change)
Unscaled (not monotone)

| -1.4400 |
0.0360 |
0.00522 |
0.00105 |
3.17e-03 |
0.00727 |
| -1.3400 |
0.0454 |
0.00578 |
0.00126 |
3.32e-03 |
0.00825 |
| -1.2400 |
0.0571 |
0.00578 |
0.00126 |
3.32e-03 |
0.00825 |
| -1.1400 |
0.0719 |
0.00578 |
0.00126 |
3.32e-03 |
0.00825 |
| -1.0400 |
0.0905 |
0.00578 |
0.00126 |
3.32e-03 |
0.00825 |
| -0.9430 |
0.1140 |
0.00578 |
0.00126 |
3.32e-03 |
0.00825 |
| -0.8430 |
0.1430 |
0.00579 |
0.00126 |
3.33e-03 |
0.00825 |
| -0.7430 |
0.1810 |
0.00581 |
0.00126 |
3.34e-03 |
0.00829 |
| -0.6430 |
0.2270 |
0.00587 |
0.00128 |
3.36e-03 |
0.00837 |
| -0.5430 |
0.2860 |
0.00587 |
0.00128 |
3.37e-03 |
0.00837 |
| -0.4430 |
0.3600 |
0.00592 |
0.00129 |
3.39e-03 |
0.00844 |
| -0.3430 |
0.4540 |
0.00596 |
0.00130 |
3.41e-03 |
0.00850 |
| -0.2430 |
0.5710 |
0.00598 |
0.00130 |
3.43e-03 |
0.00853 |
| -0.1430 |
0.7190 |
0.00606 |
0.00132 |
3.47e-03 |
0.00866 |
| -0.0433 |
0.9050 |
0.00621 |
0.00136 |
3.55e-03 |
0.00887 |
| 0.0567 |
1.1400 |
0.00618 |
0.00139 |
3.46e-03 |
0.00890 |
| 0.1570 |
1.4300 |
0.00632 |
0.00143 |
3.53e-03 |
0.00912 |
| 0.2570 |
1.8100 |
0.00608 |
0.00140 |
3.34e-03 |
0.00883 |
| 0.3570 |
2.2700 |
0.00613 |
0.00142 |
3.35e-03 |
0.00890 |
| 0.4570 |
2.8600 |
0.00587 |
0.00144 |
3.05e-03 |
0.00868 |
| 0.5570 |
3.6000 |
0.00598 |
0.00147 |
3.10e-03 |
0.00886 |
| 0.6570 |
4.5400 |
0.00612 |
0.00151 |
3.16e-03 |
0.00908 |
| 0.7570 |
5.7100 |
0.00626 |
0.00154 |
3.25e-03 |
0.00927 |
| 0.8570 |
7.1900 |
0.00655 |
0.00162 |
3.37e-03 |
0.00974 |
| 0.9570 |
9.0500 |
0.00652 |
0.00164 |
3.31e-03 |
0.00973 |
| 1.0600 |
11.4000 |
0.00738 |
0.00191 |
3.64e-03 |
0.01110 |
| 1.1600 |
14.3000 |
0.00730 |
0.00191 |
3.56e-03 |
0.01100 |
| 1.2600 |
18.1000 |
0.00763 |
0.00201 |
3.70e-03 |
0.01160 |
| 1.3600 |
22.7000 |
0.00601 |
0.00186 |
2.37e-03 |
0.00964 |
| 1.4600 |
28.6000 |
0.00572 |
0.00179 |
2.22e-03 |
0.00923 |
| 1.5600 |
36.0000 |
0.00691 |
0.00208 |
2.83e-03 |
0.01100 |
| 1.6600 |
45.4000 |
0.00620 |
0.00205 |
2.18e-03 |
0.01020 |
| 1.7600 |
57.1000 |
0.00674 |
0.00226 |
2.30e-03 |
0.01120 |
| 1.8600 |
71.9000 |
0.00717 |
0.00258 |
2.11e-03 |
0.01220 |
| 1.9600 |
90.5000 |
0.00669 |
0.00255 |
1.70e-03 |
0.01170 |
| 2.0600 |
114.0000 |
0.00685 |
0.00302 |
9.35e-04 |
0.01280 |
| 2.1600 |
143.0000 |
0.00458 |
0.00237 |
-6.69e-05 |
0.00922 |
| 2.2600 |
181.0000 |
0.00510 |
0.00267 |
-1.46e-04 |
0.01030 |
| 2.3600 |
227.0000 |
0.00471 |
0.00285 |
-8.73e-04 |
0.01030 |
Unscaled (monotone)

| -1.4400 |
0.0360 |
0.00000 |
0.00614 |
0.00105 |
0.004090 |
0.00819 |
| -1.3400 |
0.0454 |
0.00300 |
0.00614 |
0.00126 |
0.003680 |
0.00860 |
| -1.2400 |
0.0571 |
0.00300 |
0.00614 |
0.00126 |
0.003680 |
0.00860 |
| -1.1400 |
0.0719 |
0.00300 |
0.00614 |
0.00126 |
0.003680 |
0.00860 |
| -1.0400 |
0.0905 |
0.00300 |
0.00614 |
0.00126 |
0.003680 |
0.00860 |
| -0.9430 |
0.1140 |
0.00300 |
0.00614 |
0.00126 |
0.003680 |
0.00860 |
| -0.8430 |
0.1430 |
0.00601 |
0.00614 |
0.00126 |
0.003680 |
0.00860 |
| -0.7430 |
0.1810 |
0.01010 |
0.00614 |
0.00126 |
0.003670 |
0.00861 |
| -0.6430 |
0.2270 |
0.01420 |
0.00614 |
0.00128 |
0.003640 |
0.00864 |
| -0.5430 |
0.2860 |
0.01470 |
0.00614 |
0.00128 |
0.003640 |
0.00864 |
| -0.4430 |
0.3600 |
0.02790 |
0.00614 |
0.00129 |
0.003620 |
0.00866 |
| -0.3430 |
0.4540 |
0.03480 |
0.00614 |
0.00130 |
0.003600 |
0.00868 |
| -0.2430 |
0.5710 |
0.04160 |
0.00614 |
0.00130 |
0.003590 |
0.00869 |
| -0.1430 |
0.7190 |
0.05530 |
0.00614 |
0.00132 |
0.003550 |
0.00873 |
| -0.0433 |
0.9050 |
0.08310 |
0.00614 |
0.00136 |
0.003480 |
0.00880 |
| 0.0567 |
1.1400 |
0.09730 |
0.00614 |
0.00139 |
0.003420 |
0.00886 |
| 0.1570 |
1.4300 |
0.11200 |
0.00614 |
0.00143 |
0.003340 |
0.00894 |
| 0.2570 |
1.8100 |
0.11700 |
0.00614 |
0.00140 |
0.003390 |
0.00889 |
| 0.3570 |
2.2700 |
0.12100 |
0.00614 |
0.00142 |
0.003360 |
0.00892 |
| 0.4570 |
2.8600 |
0.16100 |
0.00614 |
0.00144 |
0.003330 |
0.00895 |
| 0.5570 |
3.6000 |
0.18200 |
0.00614 |
0.00147 |
0.003260 |
0.00902 |
| 0.6570 |
4.5400 |
0.20200 |
0.00614 |
0.00151 |
0.003180 |
0.00910 |
| 0.7570 |
5.7100 |
0.23700 |
0.00614 |
0.00154 |
0.003130 |
0.00915 |
| 0.8570 |
7.1900 |
0.26900 |
0.00614 |
0.00162 |
0.002960 |
0.00932 |
| 0.9570 |
9.0500 |
0.29600 |
0.00614 |
0.00164 |
0.002930 |
0.00935 |
| 1.0600 |
11.4000 |
0.33000 |
0.00614 |
0.00191 |
0.002400 |
0.00988 |
| 1.1600 |
14.3000 |
0.36900 |
0.00614 |
0.00191 |
0.002400 |
0.00988 |
| 1.2600 |
18.1000 |
0.39200 |
0.00614 |
0.00201 |
0.002210 |
0.01010 |
| 1.3600 |
22.7000 |
0.41500 |
0.00614 |
0.00186 |
0.002500 |
0.00978 |
| 1.4600 |
28.6000 |
0.46700 |
0.00614 |
0.00179 |
0.002630 |
0.00965 |
| 1.5600 |
36.0000 |
0.52000 |
0.00614 |
0.00208 |
0.002060 |
0.01020 |
| 1.6600 |
45.4000 |
0.56200 |
0.00614 |
0.00205 |
0.002120 |
0.01020 |
| 1.7600 |
57.1000 |
0.59400 |
0.00614 |
0.00226 |
0.001710 |
0.01060 |
| 1.8600 |
71.9000 |
0.64900 |
0.00614 |
0.00258 |
0.001080 |
0.01120 |
| 1.9600 |
90.5000 |
0.69000 |
0.00614 |
0.00255 |
0.001150 |
0.01110 |
| 2.0600 |
114.0000 |
0.74000 |
0.00614 |
0.00302 |
0.000225 |
0.01210 |
| 2.1600 |
143.0000 |
0.77800 |
0.00484 |
0.00237 |
0.000193 |
0.00948 |
| 2.2600 |
181.0000 |
0.80300 |
0.00484 |
0.00267 |
-0.000406 |
0.01010 |
| 2.3600 |
227.0000 |
0.83000 |
0.00471 |
0.00285 |
-0.000873 |
0.01030 |
VE scale (1 minus risk / placebo risk) (monotone)

| -1.4400 |
0.0360 |
0.319 |
0.140 |
0.0440 |
0.594 |
| -1.3400 |
0.0454 |
0.319 |
0.169 |
-0.0113 |
0.649 |
| -1.2400 |
0.0571 |
0.319 |
0.169 |
-0.0113 |
0.649 |
| -1.1400 |
0.0719 |
0.319 |
0.169 |
-0.0113 |
0.649 |
| -1.0400 |
0.0905 |
0.319 |
0.169 |
-0.0113 |
0.649 |
| -0.9430 |
0.1140 |
0.319 |
0.169 |
-0.0113 |
0.649 |
| -0.8430 |
0.1430 |
0.319 |
0.169 |
-0.0113 |
0.649 |
| -0.7430 |
0.1810 |
0.319 |
0.169 |
-0.0127 |
0.651 |
| -0.6430 |
0.2270 |
0.319 |
0.171 |
-0.0164 |
0.655 |
| -0.5430 |
0.2860 |
0.319 |
0.171 |
-0.0164 |
0.655 |
| -0.4430 |
0.3600 |
0.319 |
0.173 |
-0.0195 |
0.658 |
| -0.3430 |
0.4540 |
0.319 |
0.174 |
-0.0222 |
0.660 |
| -0.2430 |
0.5710 |
0.319 |
0.175 |
-0.0232 |
0.661 |
| -0.1430 |
0.7190 |
0.319 |
0.177 |
-0.0288 |
0.667 |
| -0.0433 |
0.9050 |
0.319 |
0.182 |
-0.0380 |
0.676 |
| 0.0567 |
1.1400 |
0.319 |
0.186 |
-0.0457 |
0.684 |
| 0.1570 |
1.4300 |
0.319 |
0.192 |
-0.0564 |
0.695 |
| 0.2570 |
1.8100 |
0.319 |
0.188 |
-0.0494 |
0.688 |
| 0.3570 |
2.2700 |
0.319 |
0.190 |
-0.0534 |
0.692 |
| 0.4570 |
2.8600 |
0.319 |
0.193 |
-0.0583 |
0.696 |
| 0.5570 |
3.6000 |
0.319 |
0.197 |
-0.0669 |
0.705 |
| 0.6570 |
4.5400 |
0.319 |
0.203 |
-0.0785 |
0.717 |
| 0.7570 |
5.7100 |
0.319 |
0.206 |
-0.0849 |
0.723 |
| 0.8570 |
7.1900 |
0.319 |
0.218 |
-0.1080 |
0.746 |
| 0.9570 |
9.0500 |
0.319 |
0.220 |
-0.1120 |
0.750 |
| 1.0600 |
11.4000 |
0.319 |
0.256 |
-0.1830 |
0.821 |
| 1.1600 |
14.3000 |
0.319 |
0.256 |
-0.1830 |
0.821 |
| 1.2600 |
18.1000 |
0.319 |
0.269 |
-0.2090 |
0.847 |
| 1.3600 |
22.7000 |
0.319 |
0.249 |
-0.1690 |
0.807 |
| 1.4600 |
28.6000 |
0.319 |
0.240 |
-0.1510 |
0.790 |
| 1.5600 |
36.0000 |
0.319 |
0.279 |
-0.2290 |
0.867 |
| 1.6600 |
45.4000 |
0.319 |
0.275 |
-0.2200 |
0.858 |
| 1.7600 |
57.1000 |
0.319 |
0.304 |
-0.2760 |
0.914 |
| 1.8600 |
71.9000 |
0.319 |
0.347 |
-0.3600 |
0.998 |
| 1.9600 |
90.5000 |
0.319 |
0.342 |
-0.3510 |
0.989 |
| 2.0600 |
114.0000 |
0.319 |
0.405 |
-0.4750 |
1.110 |
| 2.1600 |
143.0000 |
0.464 |
0.298 |
-0.1210 |
1.050 |
| 2.2600 |
181.0000 |
0.464 |
0.337 |
-0.1960 |
1.120 |
| 2.3600 |
227.0000 |
0.478 |
0.356 |
-0.2210 |
1.180 |
nAb ID50 B.1.351
Vaccine
Unscaled (not monotone)

| 1.3 |
20.0 |
0.00522 |
0.00105 |
3.17e-03 |
0.00727 |
| 1.4 |
25.2 |
0.00600 |
0.00132 |
3.41e-03 |
0.00858 |
| 1.5 |
31.7 |
0.00600 |
0.00132 |
3.41e-03 |
0.00858 |
| 1.6 |
39.9 |
0.00600 |
0.00132 |
3.41e-03 |
0.00858 |
| 1.7 |
50.2 |
0.00600 |
0.00132 |
3.41e-03 |
0.00858 |
| 1.8 |
63.2 |
0.00600 |
0.00132 |
3.41e-03 |
0.00858 |
| 1.9 |
79.6 |
0.00604 |
0.00133 |
3.43e-03 |
0.00865 |
| 2.0 |
100.0 |
0.00610 |
0.00136 |
3.44e-03 |
0.00877 |
| 2.1 |
126.0 |
0.00612 |
0.00137 |
3.44e-03 |
0.00880 |
| 2.2 |
159.0 |
0.00618 |
0.00139 |
3.45e-03 |
0.00891 |
| 2.3 |
200.0 |
0.00572 |
0.00132 |
3.14e-03 |
0.00830 |
| 2.4 |
252.0 |
0.00573 |
0.00131 |
3.15e-03 |
0.00830 |
| 2.5 |
317.0 |
0.00577 |
0.00132 |
3.18e-03 |
0.00836 |
| 2.6 |
399.0 |
0.00583 |
0.00134 |
3.19e-03 |
0.00846 |
| 2.7 |
502.0 |
0.00555 |
0.00131 |
2.99e-03 |
0.00811 |
| 2.8 |
632.0 |
0.00567 |
0.00134 |
3.05e-03 |
0.00830 |
| 2.9 |
796.0 |
0.00569 |
0.00134 |
3.06e-03 |
0.00831 |
| 3.0 |
1000.0 |
0.00562 |
0.00137 |
2.94e-03 |
0.00831 |
| 3.1 |
1260.0 |
0.00542 |
0.00135 |
2.77e-03 |
0.00807 |
| 3.2 |
1590.0 |
0.00559 |
0.00145 |
2.76e-03 |
0.00843 |
| 3.3 |
2000.0 |
0.00570 |
0.00147 |
2.82e-03 |
0.00857 |
| 3.4 |
2520.0 |
0.00546 |
0.00144 |
2.65e-03 |
0.00827 |
| 3.5 |
3170.0 |
0.00465 |
0.00133 |
2.04e-03 |
0.00726 |
| 3.6 |
3990.0 |
0.00479 |
0.00137 |
2.10e-03 |
0.00747 |
| 3.7 |
5020.0 |
0.00333 |
0.00116 |
1.06e-03 |
0.00560 |
| 3.8 |
6320.0 |
0.00321 |
0.00116 |
9.31e-04 |
0.00548 |
| 3.9 |
7960.0 |
0.00322 |
0.00125 |
7.69e-04 |
0.00568 |
| 4.0 |
10000.0 |
0.00237 |
0.00124 |
-5.19e-05 |
0.00479 |
Unscaled (monotone)

| 1.3 |
20.0 |
0.0000 |
0.00596 |
0.00105 |
3.91e-03 |
0.00801 |
| 1.4 |
25.2 |
0.0187 |
0.00596 |
0.00132 |
3.38e-03 |
0.00855 |
| 1.5 |
31.7 |
0.0187 |
0.00596 |
0.00132 |
3.38e-03 |
0.00855 |
| 1.6 |
39.9 |
0.0187 |
0.00596 |
0.00132 |
3.38e-03 |
0.00855 |
| 1.7 |
50.2 |
0.0187 |
0.00596 |
0.00132 |
3.38e-03 |
0.00855 |
| 1.8 |
63.2 |
0.0187 |
0.00596 |
0.00132 |
3.38e-03 |
0.00855 |
| 1.9 |
79.6 |
0.0222 |
0.00596 |
0.00133 |
3.35e-03 |
0.00858 |
| 2.0 |
100.0 |
0.0287 |
0.00596 |
0.00136 |
3.30e-03 |
0.00863 |
| 2.1 |
126.0 |
0.0298 |
0.00596 |
0.00137 |
3.28e-03 |
0.00865 |
| 2.2 |
159.0 |
0.0361 |
0.00596 |
0.00139 |
3.23e-03 |
0.00869 |
| 2.3 |
200.0 |
0.0466 |
0.00576 |
0.00132 |
3.18e-03 |
0.00834 |
| 2.4 |
252.0 |
0.0502 |
0.00576 |
0.00131 |
3.19e-03 |
0.00834 |
| 2.5 |
317.0 |
0.0600 |
0.00576 |
0.00132 |
3.17e-03 |
0.00835 |
| 2.6 |
399.0 |
0.0662 |
0.00576 |
0.00134 |
3.13e-03 |
0.00840 |
| 2.7 |
502.0 |
0.0667 |
0.00564 |
0.00131 |
3.08e-03 |
0.00820 |
| 2.8 |
632.0 |
0.0960 |
0.00564 |
0.00134 |
3.01e-03 |
0.00826 |
| 2.9 |
796.0 |
0.1010 |
0.00564 |
0.00134 |
3.01e-03 |
0.00827 |
| 3.0 |
1000.0 |
0.1310 |
0.00562 |
0.00137 |
2.94e-03 |
0.00831 |
| 3.1 |
1260.0 |
0.1400 |
0.00557 |
0.00135 |
2.92e-03 |
0.00821 |
| 3.2 |
1590.0 |
0.1650 |
0.00557 |
0.00145 |
2.73e-03 |
0.00840 |
| 3.3 |
2000.0 |
0.1930 |
0.00557 |
0.00147 |
2.69e-03 |
0.00844 |
| 3.4 |
2520.0 |
0.2040 |
0.00546 |
0.00144 |
2.65e-03 |
0.00827 |
| 3.5 |
3170.0 |
0.2340 |
0.00472 |
0.00133 |
2.11e-03 |
0.00733 |
| 3.6 |
3990.0 |
0.2860 |
0.00472 |
0.00137 |
2.03e-03 |
0.00740 |
| 3.7 |
5020.0 |
0.3750 |
0.00333 |
0.00116 |
1.06e-03 |
0.00560 |
| 3.8 |
6320.0 |
0.4160 |
0.00321 |
0.00116 |
9.40e-04 |
0.00549 |
| 3.9 |
7960.0 |
0.4900 |
0.00321 |
0.00125 |
7.60e-04 |
0.00567 |
| 4.0 |
10000.0 |
0.6000 |
0.00237 |
0.00124 |
-5.19e-05 |
0.00479 |
VE scale (1 minus risk / placebo risk) (monotone)

| 1.3 |
20.0 |
0.339 |
0.139 |
0.06600 |
0.611 |
| 1.4 |
25.2 |
0.339 |
0.175 |
-0.00512 |
0.682 |
| 1.5 |
31.7 |
0.339 |
0.175 |
-0.00512 |
0.682 |
| 1.6 |
39.9 |
0.339 |
0.175 |
-0.00512 |
0.682 |
| 1.7 |
50.2 |
0.339 |
0.175 |
-0.00512 |
0.682 |
| 1.8 |
63.2 |
0.339 |
0.175 |
-0.00512 |
0.682 |
| 1.9 |
79.6 |
0.339 |
0.177 |
-0.00899 |
0.686 |
| 2.0 |
100.0 |
0.339 |
0.181 |
-0.01580 |
0.693 |
| 2.1 |
126.0 |
0.339 |
0.182 |
-0.01800 |
0.695 |
| 2.2 |
159.0 |
0.339 |
0.185 |
-0.02450 |
0.702 |
| 2.3 |
200.0 |
0.361 |
0.173 |
0.02160 |
0.701 |
| 2.4 |
252.0 |
0.361 |
0.173 |
0.02240 |
0.700 |
| 2.5 |
317.0 |
0.361 |
0.174 |
0.02010 |
0.702 |
| 2.6 |
399.0 |
0.361 |
0.177 |
0.01450 |
0.708 |
| 2.7 |
502.0 |
0.375 |
0.171 |
0.03990 |
0.710 |
| 2.8 |
632.0 |
0.375 |
0.175 |
0.03140 |
0.718 |
| 2.9 |
796.0 |
0.375 |
0.175 |
0.03110 |
0.718 |
| 3.0 |
1000.0 |
0.377 |
0.179 |
0.02590 |
0.728 |
| 3.1 |
1260.0 |
0.383 |
0.176 |
0.03750 |
0.728 |
| 3.2 |
1590.0 |
0.383 |
0.188 |
0.01330 |
0.752 |
| 3.3 |
2000.0 |
0.383 |
0.191 |
0.00822 |
0.757 |
| 3.4 |
2520.0 |
0.395 |
0.186 |
0.02960 |
0.759 |
| 3.5 |
3170.0 |
0.477 |
0.167 |
0.15000 |
0.803 |
| 3.6 |
3990.0 |
0.477 |
0.171 |
0.14100 |
0.813 |
| 3.7 |
5020.0 |
0.631 |
0.137 |
0.36300 |
0.899 |
| 3.8 |
6320.0 |
0.644 |
0.137 |
0.37600 |
0.911 |
| 3.9 |
7960.0 |
0.644 |
0.147 |
0.35500 |
0.932 |
| 4.0 |
10000.0 |
0.737 |
0.142 |
0.46000 |
1.010 |
Placebo
Not monotone

| 1.3 |
20.0 |
0.00902 |
0.00139 |
0.006290 |
0.01170 |
| 1.4 |
25.2 |
0.00614 |
0.00160 |
0.003010 |
0.00927 |
| 1.5 |
31.7 |
0.00614 |
0.00160 |
0.003010 |
0.00927 |
| 1.6 |
39.9 |
0.00614 |
0.00160 |
0.003010 |
0.00927 |
| 1.7 |
50.2 |
0.00614 |
0.00160 |
0.003010 |
0.00927 |
| 1.8 |
63.2 |
0.00571 |
0.00152 |
0.002730 |
0.00869 |
| 1.9 |
79.6 |
0.00547 |
0.00150 |
0.002530 |
0.00842 |
| 2.0 |
100.0 |
0.00545 |
0.00155 |
0.002410 |
0.00848 |
| 2.1 |
126.0 |
0.00513 |
0.00151 |
0.002170 |
0.00808 |
| 2.2 |
159.0 |
0.00458 |
0.00147 |
0.001700 |
0.00747 |
| 2.3 |
200.0 |
0.00421 |
0.00141 |
0.001450 |
0.00698 |
| 2.4 |
252.0 |
0.00345 |
0.00128 |
0.000951 |
0.00595 |
| 2.5 |
317.0 |
0.00351 |
0.00143 |
0.000711 |
0.00632 |
Monotone

| 1.3 |
20.0 |
0.000 |
0.00902 |
0.00139 |
0.006290 |
0.01170 |
| 1.4 |
25.2 |
0.280 |
0.00614 |
0.00160 |
0.003010 |
0.00927 |
| 1.5 |
31.7 |
0.280 |
0.00614 |
0.00160 |
0.003010 |
0.00927 |
| 1.6 |
39.9 |
0.280 |
0.00614 |
0.00160 |
0.003010 |
0.00927 |
| 1.7 |
50.2 |
0.280 |
0.00614 |
0.00160 |
0.003010 |
0.00927 |
| 1.8 |
63.2 |
0.282 |
0.00571 |
0.00152 |
0.002730 |
0.00869 |
| 1.9 |
79.6 |
0.297 |
0.00547 |
0.00150 |
0.002530 |
0.00842 |
| 2.0 |
100.0 |
0.319 |
0.00545 |
0.00155 |
0.002410 |
0.00848 |
| 2.1 |
126.0 |
0.330 |
0.00513 |
0.00151 |
0.002170 |
0.00808 |
| 2.2 |
159.0 |
0.360 |
0.00458 |
0.00147 |
0.001700 |
0.00747 |
| 2.3 |
200.0 |
0.384 |
0.00421 |
0.00141 |
0.001450 |
0.00698 |
| 2.4 |
252.0 |
0.390 |
0.00348 |
0.00128 |
0.000982 |
0.00598 |
| 2.5 |
317.0 |
0.422 |
0.00348 |
0.00143 |
0.000679 |
0.00628 |
Vaccine (change)
Unscaled (not monotone)

| -1.2500 |
0.0562 |
0.00522 |
0.00105 |
0.003170 |
0.00727 |
| -1.1500 |
0.0707 |
0.00582 |
0.00127 |
0.003340 |
0.00830 |
| -1.0500 |
0.0890 |
0.00582 |
0.00127 |
0.003340 |
0.00830 |
| -0.9500 |
0.1120 |
0.00582 |
0.00127 |
0.003340 |
0.00830 |
| -0.8500 |
0.1410 |
0.00586 |
0.00127 |
0.003360 |
0.00836 |
| -0.7500 |
0.1780 |
0.00589 |
0.00128 |
0.003380 |
0.00840 |
| -0.6500 |
0.2240 |
0.00589 |
0.00128 |
0.003380 |
0.00840 |
| -0.5500 |
0.2820 |
0.00590 |
0.00128 |
0.003380 |
0.00841 |
| -0.4500 |
0.3540 |
0.00596 |
0.00130 |
0.003410 |
0.00851 |
| -0.3500 |
0.4460 |
0.00601 |
0.00132 |
0.003430 |
0.00859 |
| -0.2500 |
0.5620 |
0.00602 |
0.00131 |
0.003440 |
0.00859 |
| -0.1500 |
0.7070 |
0.00604 |
0.00132 |
0.003450 |
0.00862 |
| -0.0504 |
0.8900 |
0.00607 |
0.00133 |
0.003470 |
0.00867 |
| 0.0496 |
1.1200 |
0.00611 |
0.00137 |
0.003420 |
0.00880 |
| 0.1500 |
1.4100 |
0.00613 |
0.00138 |
0.003430 |
0.00884 |
| 0.2500 |
1.7800 |
0.00618 |
0.00139 |
0.003450 |
0.00892 |
| 0.3500 |
2.2400 |
0.00632 |
0.00143 |
0.003520 |
0.00912 |
| 0.4500 |
2.8200 |
0.00589 |
0.00139 |
0.003170 |
0.00862 |
| 0.5500 |
3.5400 |
0.00606 |
0.00144 |
0.003240 |
0.00887 |
| 0.6500 |
4.4600 |
0.00627 |
0.00151 |
0.003310 |
0.00923 |
| 0.7500 |
5.6200 |
0.00639 |
0.00153 |
0.003400 |
0.00938 |
| 0.8500 |
7.0700 |
0.00631 |
0.00154 |
0.003290 |
0.00933 |
| 0.9500 |
8.9000 |
0.00618 |
0.00155 |
0.003150 |
0.00921 |
| 1.0500 |
11.2000 |
0.00575 |
0.00153 |
0.002760 |
0.00875 |
| 1.1500 |
14.1000 |
0.00523 |
0.00148 |
0.002330 |
0.00812 |
| 1.2500 |
17.8000 |
0.00505 |
0.00146 |
0.002190 |
0.00791 |
| 1.3500 |
22.4000 |
0.00440 |
0.00137 |
0.001720 |
0.00708 |
| 1.4500 |
28.2000 |
0.00458 |
0.00143 |
0.001780 |
0.00739 |
| 1.5500 |
35.4000 |
0.00493 |
0.00156 |
0.001860 |
0.00799 |
| 1.6500 |
44.6000 |
0.00433 |
0.00151 |
0.001380 |
0.00728 |
| 1.7500 |
56.2000 |
0.00453 |
0.00160 |
0.001410 |
0.00766 |
| 1.8500 |
70.7000 |
0.00553 |
0.00198 |
0.001640 |
0.00942 |
| 1.9500 |
89.0000 |
0.00631 |
0.00220 |
0.002010 |
0.01060 |
| 2.0500 |
112.0000 |
0.00737 |
0.00258 |
0.002310 |
0.01240 |
| 2.1500 |
141.0000 |
0.00558 |
0.00239 |
0.000907 |
0.01030 |
| 2.2500 |
178.0000 |
0.00521 |
0.00240 |
0.000507 |
0.00992 |
| 2.3500 |
224.0000 |
0.00520 |
0.00271 |
-0.000110 |
0.01050 |
Unscaled (monotone)

| -1.2500 |
0.0562 |
0.00000 |
0.00600 |
0.00105 |
3.95e-03 |
0.00805 |
| -1.1500 |
0.0707 |
0.00601 |
0.00600 |
0.00127 |
3.52e-03 |
0.00848 |
| -1.0500 |
0.0890 |
0.00601 |
0.00600 |
0.00127 |
3.52e-03 |
0.00848 |
| -0.9500 |
0.1120 |
0.00601 |
0.00600 |
0.00127 |
3.52e-03 |
0.00848 |
| -0.8500 |
0.1410 |
0.01120 |
0.00600 |
0.00127 |
3.50e-03 |
0.00850 |
| -0.7500 |
0.1780 |
0.01810 |
0.00600 |
0.00128 |
3.49e-03 |
0.00851 |
| -0.6500 |
0.2240 |
0.01810 |
0.00600 |
0.00128 |
3.49e-03 |
0.00851 |
| -0.5500 |
0.2820 |
0.02110 |
0.00600 |
0.00128 |
3.49e-03 |
0.00852 |
| -0.4500 |
0.3540 |
0.02540 |
0.00600 |
0.00130 |
3.45e-03 |
0.00855 |
| -0.3500 |
0.4460 |
0.03170 |
0.00600 |
0.00132 |
3.42e-03 |
0.00858 |
| -0.2500 |
0.5620 |
0.03470 |
0.00600 |
0.00131 |
3.43e-03 |
0.00858 |
| -0.1500 |
0.7070 |
0.04140 |
0.00600 |
0.00132 |
3.42e-03 |
0.00858 |
| -0.0504 |
0.8900 |
0.05020 |
0.00600 |
0.00133 |
3.40e-03 |
0.00860 |
| 0.0496 |
1.1200 |
0.07930 |
0.00600 |
0.00137 |
3.31e-03 |
0.00869 |
| 0.1500 |
1.4100 |
0.08310 |
0.00600 |
0.00138 |
3.30e-03 |
0.00871 |
| 0.2500 |
1.7800 |
0.08980 |
0.00600 |
0.00139 |
3.27e-03 |
0.00873 |
| 0.3500 |
2.2400 |
0.11400 |
0.00600 |
0.00143 |
3.20e-03 |
0.00880 |
| 0.4500 |
2.8200 |
0.13900 |
0.00600 |
0.00139 |
3.28e-03 |
0.00873 |
| 0.5500 |
3.5400 |
0.16200 |
0.00600 |
0.00144 |
3.19e-03 |
0.00882 |
| 0.6500 |
4.4600 |
0.18600 |
0.00600 |
0.00151 |
3.05e-03 |
0.00896 |
| 0.7500 |
5.6200 |
0.21600 |
0.00600 |
0.00153 |
3.01e-03 |
0.00899 |
| 0.8500 |
7.0700 |
0.22800 |
0.00600 |
0.00154 |
2.98e-03 |
0.00902 |
| 0.9500 |
8.9000 |
0.24500 |
0.00600 |
0.00155 |
2.97e-03 |
0.00904 |
| 1.0500 |
11.2000 |
0.27800 |
0.00575 |
0.00153 |
2.76e-03 |
0.00875 |
| 1.1500 |
14.1000 |
0.30400 |
0.00523 |
0.00148 |
2.33e-03 |
0.00812 |
| 1.2500 |
17.8000 |
0.35500 |
0.00505 |
0.00146 |
2.19e-03 |
0.00791 |
| 1.3500 |
22.4000 |
0.36900 |
0.00463 |
0.00137 |
1.95e-03 |
0.00731 |
| 1.4500 |
28.2000 |
0.39800 |
0.00463 |
0.00143 |
1.83e-03 |
0.00744 |
| 1.5500 |
35.4000 |
0.45000 |
0.00463 |
0.00156 |
1.57e-03 |
0.00770 |
| 1.6500 |
44.6000 |
0.46700 |
0.00463 |
0.00151 |
1.68e-03 |
0.00759 |
| 1.7500 |
56.2000 |
0.49300 |
0.00463 |
0.00160 |
1.51e-03 |
0.00776 |
| 1.8500 |
70.7000 |
0.54800 |
0.00463 |
0.00198 |
7.45e-04 |
0.00852 |
| 1.9500 |
89.0000 |
0.60200 |
0.00463 |
0.00220 |
3.28e-04 |
0.00894 |
| 2.0500 |
112.0000 |
0.63400 |
0.00463 |
0.00258 |
-4.28e-04 |
0.00970 |
| 2.1500 |
141.0000 |
0.66900 |
0.00463 |
0.00239 |
-4.12e-05 |
0.00931 |
| 2.2500 |
178.0000 |
0.72800 |
0.00463 |
0.00240 |
-7.25e-05 |
0.00934 |
| 2.3500 |
224.0000 |
0.78200 |
0.00463 |
0.00271 |
-6.74e-04 |
0.00994 |
VE scale (1 minus risk / placebo risk) (monotone)

| -1.2500 |
0.0562 |
0.335 |
0.139 |
6.14e-02 |
0.608 |
| -1.1500 |
0.0707 |
0.335 |
0.169 |
3.94e-03 |
0.665 |
| -1.0500 |
0.0890 |
0.335 |
0.169 |
3.94e-03 |
0.665 |
| -0.9500 |
0.1120 |
0.335 |
0.169 |
3.94e-03 |
0.665 |
| -0.8500 |
0.1410 |
0.335 |
0.170 |
1.67e-03 |
0.667 |
| -0.7500 |
0.1780 |
0.335 |
0.171 |
-3.64e-05 |
0.669 |
| -0.6500 |
0.2240 |
0.335 |
0.171 |
-3.64e-05 |
0.669 |
| -0.5500 |
0.2820 |
0.335 |
0.171 |
-4.76e-04 |
0.669 |
| -0.4500 |
0.3540 |
0.335 |
0.173 |
-5.10e-03 |
0.674 |
| -0.3500 |
0.4460 |
0.335 |
0.175 |
-8.91e-03 |
0.678 |
| -0.2500 |
0.5620 |
0.335 |
0.175 |
-8.50e-03 |
0.678 |
| -0.1500 |
0.7070 |
0.335 |
0.176 |
-9.56e-03 |
0.679 |
| -0.0504 |
0.8900 |
0.335 |
0.177 |
-1.21e-02 |
0.681 |
| 0.0496 |
1.1200 |
0.335 |
0.183 |
-2.40e-02 |
0.693 |
| 0.1500 |
1.4100 |
0.335 |
0.184 |
-2.57e-02 |
0.695 |
| 0.2500 |
1.7800 |
0.335 |
0.186 |
-2.95e-02 |
0.699 |
| 0.3500 |
2.2400 |
0.335 |
0.190 |
-3.82e-02 |
0.707 |
| 0.4500 |
2.8200 |
0.335 |
0.185 |
-2.84e-02 |
0.697 |
| 0.5500 |
3.5400 |
0.335 |
0.191 |
-4.04e-02 |
0.709 |
| 0.6500 |
4.4600 |
0.335 |
0.201 |
-5.92e-02 |
0.728 |
| 0.7500 |
5.6200 |
0.335 |
0.203 |
-6.41e-02 |
0.733 |
| 0.8500 |
7.0700 |
0.335 |
0.205 |
-6.78e-02 |
0.737 |
| 0.9500 |
8.9000 |
0.335 |
0.206 |
-6.97e-02 |
0.739 |
| 1.0500 |
11.2000 |
0.362 |
0.201 |
-3.16e-02 |
0.755 |
| 1.1500 |
14.1000 |
0.421 |
0.189 |
4.92e-02 |
0.792 |
| 1.2500 |
17.8000 |
0.440 |
0.186 |
7.61e-02 |
0.804 |
| 1.3500 |
22.4000 |
0.486 |
0.170 |
1.52e-01 |
0.820 |
| 1.4500 |
28.2000 |
0.486 |
0.179 |
1.36e-01 |
0.836 |
| 1.5500 |
35.4000 |
0.486 |
0.195 |
1.04e-01 |
0.868 |
| 1.6500 |
44.6000 |
0.486 |
0.188 |
1.18e-01 |
0.854 |
| 1.7500 |
56.2000 |
0.486 |
0.199 |
9.62e-02 |
0.876 |
| 1.8500 |
70.7000 |
0.486 |
0.247 |
1.09e-03 |
0.971 |
| 1.9500 |
89.0000 |
0.486 |
0.274 |
-5.10e-02 |
1.020 |
| 2.0500 |
112.0000 |
0.486 |
0.322 |
-1.45e-01 |
1.120 |
| 2.1500 |
141.0000 |
0.486 |
0.297 |
-9.70e-02 |
1.070 |
| 2.2500 |
178.0000 |
0.486 |
0.299 |
-1.01e-01 |
1.070 |
| 2.3500 |
224.0000 |
0.486 |
0.338 |
-1.76e-01 |
1.150 |
nAb ID50 BA.1
Vaccine
Unscaled (not monotone)

| 1.3 |
20.0 |
0.00522 |
0.00105 |
3.17e-03 |
0.00727 |
| 1.4 |
25.2 |
0.00594 |
0.00135 |
3.29e-03 |
0.00860 |
| 1.5 |
31.7 |
0.00594 |
0.00135 |
3.29e-03 |
0.00860 |
| 1.6 |
39.9 |
0.00594 |
0.00135 |
3.29e-03 |
0.00860 |
| 1.7 |
50.2 |
0.00594 |
0.00135 |
3.29e-03 |
0.00860 |
| 1.8 |
63.2 |
0.00596 |
0.00136 |
3.29e-03 |
0.00863 |
| 1.9 |
79.6 |
0.00596 |
0.00136 |
3.30e-03 |
0.00863 |
| 2.0 |
100.0 |
0.00572 |
0.00132 |
3.12e-03 |
0.00831 |
| 2.1 |
126.0 |
0.00579 |
0.00134 |
3.15e-03 |
0.00842 |
| 2.2 |
159.0 |
0.00587 |
0.00136 |
3.21e-03 |
0.00854 |
| 2.3 |
200.0 |
0.00614 |
0.00144 |
3.31e-03 |
0.00896 |
| 2.4 |
252.0 |
0.00618 |
0.00143 |
3.37e-03 |
0.00898 |
| 2.5 |
317.0 |
0.00633 |
0.00148 |
3.43e-03 |
0.00922 |
| 2.6 |
399.0 |
0.00648 |
0.00152 |
3.50e-03 |
0.00947 |
| 2.7 |
502.0 |
0.00665 |
0.00157 |
3.57e-03 |
0.00973 |
| 2.8 |
632.0 |
0.00653 |
0.00157 |
3.44e-03 |
0.00962 |
| 2.9 |
796.0 |
0.00711 |
0.00173 |
3.72e-03 |
0.01050 |
| 3.0 |
1000.0 |
0.00668 |
0.00170 |
3.34e-03 |
0.01000 |
| 3.1 |
1260.0 |
0.00699 |
0.00187 |
3.33e-03 |
0.01060 |
| 3.2 |
1590.0 |
0.00643 |
0.00181 |
2.89e-03 |
0.00998 |
| 3.3 |
2000.0 |
0.00515 |
0.00172 |
1.78e-03 |
0.00853 |
| 3.4 |
2520.0 |
0.00271 |
0.00137 |
2.84e-05 |
0.00540 |
| 3.5 |
3170.0 |
0.00202 |
0.00127 |
-4.64e-04 |
0.00451 |
Unscaled (monotone)

| 1.3 |
20.0 |
0.0000 |
0.00616 |
0.00105 |
4.11e-03 |
0.00820 |
| 1.4 |
25.2 |
0.0410 |
0.00616 |
0.00135 |
3.50e-03 |
0.00881 |
| 1.5 |
31.7 |
0.0410 |
0.00616 |
0.00135 |
3.50e-03 |
0.00881 |
| 1.6 |
39.9 |
0.0410 |
0.00616 |
0.00135 |
3.50e-03 |
0.00881 |
| 1.7 |
50.2 |
0.0410 |
0.00616 |
0.00135 |
3.50e-03 |
0.00881 |
| 1.8 |
63.2 |
0.0421 |
0.00616 |
0.00136 |
3.49e-03 |
0.00882 |
| 1.9 |
79.6 |
0.0423 |
0.00616 |
0.00136 |
3.49e-03 |
0.00882 |
| 2.0 |
100.0 |
0.0458 |
0.00616 |
0.00132 |
3.56e-03 |
0.00875 |
| 2.1 |
126.0 |
0.0547 |
0.00616 |
0.00134 |
3.52e-03 |
0.00879 |
| 2.2 |
159.0 |
0.0745 |
0.00616 |
0.00136 |
3.49e-03 |
0.00882 |
| 2.3 |
200.0 |
0.0919 |
0.00616 |
0.00144 |
3.33e-03 |
0.00898 |
| 2.4 |
252.0 |
0.1070 |
0.00616 |
0.00143 |
3.35e-03 |
0.00896 |
| 2.5 |
317.0 |
0.1280 |
0.00616 |
0.00148 |
3.26e-03 |
0.00905 |
| 2.6 |
399.0 |
0.1550 |
0.00616 |
0.00152 |
3.17e-03 |
0.00914 |
| 2.7 |
502.0 |
0.1770 |
0.00616 |
0.00157 |
3.07e-03 |
0.00924 |
| 2.8 |
632.0 |
0.1990 |
0.00616 |
0.00157 |
3.07e-03 |
0.00924 |
| 2.9 |
796.0 |
0.2680 |
0.00616 |
0.00173 |
2.77e-03 |
0.00954 |
| 3.0 |
1000.0 |
0.2990 |
0.00616 |
0.00170 |
2.82e-03 |
0.00949 |
| 3.1 |
1260.0 |
0.3780 |
0.00616 |
0.00187 |
2.49e-03 |
0.00982 |
| 3.2 |
1590.0 |
0.4070 |
0.00616 |
0.00181 |
2.61e-03 |
0.00970 |
| 3.3 |
2000.0 |
0.5210 |
0.00515 |
0.00172 |
1.78e-03 |
0.00853 |
| 3.4 |
2520.0 |
0.5930 |
0.00271 |
0.00137 |
2.84e-05 |
0.00540 |
| 3.5 |
3170.0 |
0.6630 |
0.00202 |
0.00127 |
-4.64e-04 |
0.00451 |
VE scale (1 minus risk / placebo risk) (monotone)

| 1.3 |
20.0 |
0.317 |
0.140 |
0.0422 |
0.593 |
| 1.4 |
25.2 |
0.317 |
0.182 |
-0.0389 |
0.674 |
| 1.5 |
31.7 |
0.317 |
0.182 |
-0.0389 |
0.674 |
| 1.6 |
39.9 |
0.317 |
0.182 |
-0.0389 |
0.674 |
| 1.7 |
50.2 |
0.317 |
0.182 |
-0.0389 |
0.674 |
| 1.8 |
63.2 |
0.317 |
0.183 |
-0.0411 |
0.676 |
| 1.9 |
79.6 |
0.317 |
0.183 |
-0.0408 |
0.676 |
| 2.0 |
100.0 |
0.317 |
0.178 |
-0.0310 |
0.666 |
| 2.1 |
126.0 |
0.317 |
0.181 |
-0.0364 |
0.671 |
| 2.2 |
159.0 |
0.317 |
0.183 |
-0.0406 |
0.675 |
| 2.3 |
200.0 |
0.317 |
0.194 |
-0.0619 |
0.697 |
| 2.4 |
252.0 |
0.317 |
0.192 |
-0.0595 |
0.694 |
| 2.5 |
317.0 |
0.317 |
0.198 |
-0.0715 |
0.706 |
| 2.6 |
399.0 |
0.317 |
0.204 |
-0.0833 |
0.718 |
| 2.7 |
502.0 |
0.317 |
0.211 |
-0.0966 |
0.731 |
| 2.8 |
632.0 |
0.317 |
0.211 |
-0.0970 |
0.732 |
| 2.9 |
796.0 |
0.317 |
0.232 |
-0.1370 |
0.772 |
| 3.0 |
1000.0 |
0.317 |
0.228 |
-0.1300 |
0.765 |
| 3.1 |
1260.0 |
0.317 |
0.251 |
-0.1740 |
0.809 |
| 3.2 |
1590.0 |
0.317 |
0.243 |
-0.1580 |
0.793 |
| 3.3 |
2000.0 |
0.429 |
0.220 |
-0.0022 |
0.859 |
| 3.4 |
2520.0 |
0.699 |
0.159 |
0.3880 |
1.010 |
| 3.5 |
3170.0 |
0.776 |
0.144 |
0.4940 |
1.060 |
Placebo
Not monotone

| 1.3 |
20.0 |
0.00902 |
0.00139 |
0.006290 |
0.01170 |
| 1.4 |
25.2 |
0.00598 |
0.00174 |
0.002570 |
0.00939 |
| 1.5 |
31.7 |
0.00598 |
0.00174 |
0.002570 |
0.00939 |
| 1.6 |
39.9 |
0.00598 |
0.00174 |
0.002570 |
0.00939 |
| 1.7 |
50.2 |
0.00605 |
0.00175 |
0.002620 |
0.00949 |
| 1.8 |
63.2 |
0.00622 |
0.00184 |
0.002620 |
0.00983 |
| 1.9 |
79.6 |
0.00501 |
0.00163 |
0.001820 |
0.00820 |
| 2.0 |
100.0 |
0.00474 |
0.00166 |
0.001490 |
0.00798 |
| 2.1 |
126.0 |
0.00356 |
0.00159 |
0.000438 |
0.00669 |
| 2.2 |
159.0 |
0.00311 |
0.00154 |
0.000102 |
0.00612 |
| 2.3 |
200.0 |
0.00277 |
0.00156 |
-0.000294 |
0.00583 |
| 2.4 |
252.0 |
0.00228 |
0.00147 |
-0.000604 |
0.00516 |
Monotone

| 1.3 |
20.0 |
0.000 |
0.00902 |
0.00139 |
0.006290 |
0.01170 |
| 1.4 |
25.2 |
0.263 |
0.00604 |
0.00174 |
0.002630 |
0.00946 |
| 1.5 |
31.7 |
0.263 |
0.00604 |
0.00174 |
0.002630 |
0.00946 |
| 1.6 |
39.9 |
0.263 |
0.00604 |
0.00174 |
0.002630 |
0.00946 |
| 1.7 |
50.2 |
0.269 |
0.00604 |
0.00175 |
0.002610 |
0.00948 |
| 1.8 |
63.2 |
0.295 |
0.00604 |
0.00184 |
0.002440 |
0.00965 |
| 1.9 |
79.6 |
0.299 |
0.00501 |
0.00163 |
0.001820 |
0.00820 |
| 2.0 |
100.0 |
0.325 |
0.00474 |
0.00166 |
0.001490 |
0.00798 |
| 2.1 |
126.0 |
0.358 |
0.00356 |
0.00159 |
0.000438 |
0.00669 |
| 2.2 |
159.0 |
0.382 |
0.00311 |
0.00154 |
0.000102 |
0.00612 |
| 2.3 |
200.0 |
0.436 |
0.00277 |
0.00156 |
-0.000294 |
0.00583 |
| 2.4 |
252.0 |
0.452 |
0.00228 |
0.00147 |
-0.000604 |
0.00516 |
Vaccine (change)
Unscaled (not monotone)

| -0.959 |
0.110 |
0.00522 |
0.00105 |
3.17e-03 |
0.00727 |
| -0.859 |
0.138 |
0.00559 |
0.00124 |
3.16e-03 |
0.00802 |
| -0.759 |
0.174 |
0.00560 |
0.00125 |
3.16e-03 |
0.00805 |
| -0.659 |
0.219 |
0.00563 |
0.00125 |
3.18e-03 |
0.00808 |
| -0.559 |
0.276 |
0.00563 |
0.00125 |
3.18e-03 |
0.00808 |
| -0.459 |
0.348 |
0.00563 |
0.00125 |
3.18e-03 |
0.00808 |
| -0.359 |
0.437 |
0.00565 |
0.00125 |
3.19e-03 |
0.00811 |
| -0.259 |
0.551 |
0.00566 |
0.00126 |
3.20e-03 |
0.00812 |
| -0.159 |
0.693 |
0.00567 |
0.00126 |
3.20e-03 |
0.00813 |
| -0.059 |
0.873 |
0.00545 |
0.00123 |
3.03e-03 |
0.00787 |
| 0.041 |
1.100 |
0.00573 |
0.00136 |
3.06e-03 |
0.00839 |
| 0.141 |
1.380 |
0.00590 |
0.00141 |
3.14e-03 |
0.00866 |
| 0.241 |
1.740 |
0.00591 |
0.00140 |
3.16e-03 |
0.00866 |
| 0.341 |
2.190 |
0.00615 |
0.00147 |
3.26e-03 |
0.00903 |
| 0.441 |
2.760 |
0.00590 |
0.00144 |
3.07e-03 |
0.00872 |
| 0.541 |
3.480 |
0.00596 |
0.00145 |
3.13e-03 |
0.00880 |
| 0.641 |
4.370 |
0.00607 |
0.00148 |
3.16e-03 |
0.00897 |
| 0.741 |
5.510 |
0.00582 |
0.00146 |
2.97e-03 |
0.00868 |
| 0.841 |
6.930 |
0.00538 |
0.00143 |
2.58e-03 |
0.00818 |
| 0.941 |
8.730 |
0.00563 |
0.00155 |
2.59e-03 |
0.00867 |
| 1.040 |
11.000 |
0.00587 |
0.00161 |
2.71e-03 |
0.00903 |
| 1.140 |
13.800 |
0.00536 |
0.00155 |
2.32e-03 |
0.00839 |
| 1.240 |
17.400 |
0.00575 |
0.00166 |
2.51e-03 |
0.00900 |
| 1.340 |
21.900 |
0.00532 |
0.00168 |
2.03e-03 |
0.00860 |
| 1.440 |
27.600 |
0.00561 |
0.00180 |
2.09e-03 |
0.00913 |
| 1.540 |
34.800 |
0.00526 |
0.00172 |
1.89e-03 |
0.00863 |
| 1.640 |
43.700 |
0.00654 |
0.00210 |
2.43e-03 |
0.01070 |
| 1.740 |
55.100 |
0.00661 |
0.00227 |
2.16e-03 |
0.01110 |
| 1.840 |
69.300 |
0.00752 |
0.00275 |
2.12e-03 |
0.01290 |
| 1.940 |
87.300 |
0.00740 |
0.00280 |
1.92e-03 |
0.01290 |
| 2.040 |
110.000 |
0.00574 |
0.00291 |
5.07e-05 |
0.01140 |
Unscaled (monotone)

| -0.959 |
0.110 |
0.00000 |
0.00572 |
0.00105 |
3.67e-03 |
0.00777 |
| -0.859 |
0.138 |
0.00625 |
0.00572 |
0.00124 |
3.29e-03 |
0.00816 |
| -0.759 |
0.174 |
0.00734 |
0.00572 |
0.00125 |
3.28e-03 |
0.00817 |
| -0.659 |
0.219 |
0.01140 |
0.00572 |
0.00125 |
3.27e-03 |
0.00818 |
| -0.559 |
0.276 |
0.01140 |
0.00572 |
0.00125 |
3.27e-03 |
0.00818 |
| -0.459 |
0.348 |
0.01140 |
0.00572 |
0.00125 |
3.27e-03 |
0.00818 |
| -0.359 |
0.437 |
0.01860 |
0.00572 |
0.00125 |
3.27e-03 |
0.00818 |
| -0.259 |
0.551 |
0.02180 |
0.00572 |
0.00126 |
3.26e-03 |
0.00819 |
| -0.159 |
0.693 |
0.02480 |
0.00572 |
0.00126 |
3.26e-03 |
0.00819 |
| -0.059 |
0.873 |
0.03490 |
0.00572 |
0.00123 |
3.31e-03 |
0.00814 |
| 0.041 |
1.100 |
0.09180 |
0.00572 |
0.00136 |
3.06e-03 |
0.00839 |
| 0.141 |
1.380 |
0.12000 |
0.00572 |
0.00141 |
2.96e-03 |
0.00849 |
| 0.241 |
1.740 |
0.12700 |
0.00572 |
0.00140 |
2.97e-03 |
0.00848 |
| 0.341 |
2.190 |
0.17400 |
0.00572 |
0.00147 |
2.84e-03 |
0.00861 |
| 0.441 |
2.760 |
0.18200 |
0.00572 |
0.00144 |
2.90e-03 |
0.00855 |
| 0.541 |
3.480 |
0.20800 |
0.00572 |
0.00145 |
2.89e-03 |
0.00856 |
| 0.641 |
4.370 |
0.21900 |
0.00572 |
0.00148 |
2.82e-03 |
0.00863 |
| 0.741 |
5.510 |
0.23100 |
0.00572 |
0.00146 |
2.87e-03 |
0.00858 |
| 0.841 |
6.930 |
0.25000 |
0.00570 |
0.00143 |
2.90e-03 |
0.00850 |
| 0.941 |
8.730 |
0.27400 |
0.00570 |
0.00155 |
2.66e-03 |
0.00874 |
| 1.040 |
11.000 |
0.30700 |
0.00570 |
0.00161 |
2.54e-03 |
0.00886 |
| 1.140 |
13.800 |
0.35700 |
0.00570 |
0.00155 |
2.66e-03 |
0.00873 |
| 1.240 |
17.400 |
0.39900 |
0.00570 |
0.00166 |
2.45e-03 |
0.00894 |
| 1.340 |
21.900 |
0.43100 |
0.00570 |
0.00168 |
2.41e-03 |
0.00898 |
| 1.440 |
27.600 |
0.45700 |
0.00570 |
0.00180 |
2.18e-03 |
0.00922 |
| 1.540 |
34.800 |
0.51200 |
0.00570 |
0.00172 |
2.33e-03 |
0.00907 |
| 1.640 |
43.700 |
0.57000 |
0.00570 |
0.00210 |
1.59e-03 |
0.00981 |
| 1.740 |
55.100 |
0.60600 |
0.00570 |
0.00227 |
1.25e-03 |
0.01020 |
| 1.840 |
69.300 |
0.66500 |
0.00570 |
0.00275 |
3.00e-04 |
0.01110 |
| 1.940 |
87.300 |
0.73500 |
0.00570 |
0.00280 |
2.19e-04 |
0.01120 |
| 2.040 |
110.000 |
0.77600 |
0.00570 |
0.00291 |
4.30e-06 |
0.01140 |
VE scale (1 minus risk / placebo risk) (monotone)

| -0.959 |
0.110 |
0.365 |
0.137 |
0.09590 |
0.634 |
| -0.859 |
0.138 |
0.365 |
0.163 |
0.04580 |
0.685 |
| -0.759 |
0.174 |
0.365 |
0.164 |
0.04430 |
0.686 |
| -0.659 |
0.219 |
0.365 |
0.164 |
0.04310 |
0.687 |
| -0.559 |
0.276 |
0.365 |
0.164 |
0.04310 |
0.687 |
| -0.459 |
0.348 |
0.365 |
0.164 |
0.04310 |
0.687 |
| -0.359 |
0.437 |
0.365 |
0.165 |
0.04230 |
0.688 |
| -0.259 |
0.551 |
0.365 |
0.165 |
0.04180 |
0.688 |
| -0.159 |
0.693 |
0.365 |
0.165 |
0.04140 |
0.689 |
| -0.059 |
0.873 |
0.365 |
0.162 |
0.04750 |
0.683 |
| 0.041 |
1.100 |
0.365 |
0.178 |
0.01560 |
0.715 |
| 0.141 |
1.380 |
0.365 |
0.185 |
0.00242 |
0.728 |
| 0.241 |
1.740 |
0.365 |
0.184 |
0.00386 |
0.726 |
| 0.341 |
2.190 |
0.365 |
0.193 |
-0.01370 |
0.744 |
| 0.441 |
2.760 |
0.365 |
0.190 |
-0.00638 |
0.737 |
| 0.541 |
3.480 |
0.365 |
0.190 |
-0.00748 |
0.738 |
| 0.641 |
4.370 |
0.365 |
0.195 |
-0.01620 |
0.746 |
| 0.741 |
5.510 |
0.365 |
0.191 |
-0.01010 |
0.740 |
| 0.841 |
6.930 |
0.368 |
0.188 |
0.00042 |
0.736 |
| 0.941 |
8.730 |
0.368 |
0.204 |
-0.03090 |
0.767 |
| 1.040 |
11.000 |
0.368 |
0.211 |
-0.04630 |
0.782 |
| 1.140 |
13.800 |
0.368 |
0.203 |
-0.03000 |
0.766 |
| 1.240 |
17.400 |
0.368 |
0.217 |
-0.05780 |
0.794 |
| 1.340 |
21.900 |
0.368 |
0.220 |
-0.06290 |
0.799 |
| 1.440 |
27.600 |
0.368 |
0.236 |
-0.09390 |
0.830 |
| 1.540 |
34.800 |
0.368 |
0.225 |
-0.07360 |
0.810 |
| 1.640 |
43.700 |
0.368 |
0.275 |
-0.17100 |
0.908 |
| 1.740 |
55.100 |
0.368 |
0.298 |
-0.21600 |
0.952 |
| 1.840 |
69.300 |
0.368 |
0.361 |
-0.34000 |
1.080 |
| 1.940 |
87.300 |
0.368 |
0.367 |
-0.35100 |
1.090 |
| 2.040 |
110.000 |
0.368 |
0.381 |
-0.37900 |
1.120 |
nAb ID50 BA.2
Vaccine
Unscaled (not monotone)

| 1.3 |
20.0 |
0.00522 |
0.00105 |
3.17e-03 |
0.00727 |
| 1.4 |
25.2 |
0.00594 |
0.00136 |
3.29e-03 |
0.00860 |
| 1.5 |
31.7 |
0.00594 |
0.00136 |
3.29e-03 |
0.00860 |
| 1.6 |
39.9 |
0.00594 |
0.00136 |
3.29e-03 |
0.00860 |
| 1.7 |
50.2 |
0.00596 |
0.00136 |
3.29e-03 |
0.00864 |
| 1.8 |
63.2 |
0.00572 |
0.00133 |
3.11e-03 |
0.00833 |
| 1.9 |
79.6 |
0.00572 |
0.00133 |
3.11e-03 |
0.00833 |
| 2.0 |
100.0 |
0.00572 |
0.00132 |
3.12e-03 |
0.00831 |
| 2.1 |
126.0 |
0.00575 |
0.00133 |
3.14e-03 |
0.00835 |
| 2.2 |
159.0 |
0.00574 |
0.00132 |
3.15e-03 |
0.00833 |
| 2.3 |
200.0 |
0.00582 |
0.00135 |
3.19e-03 |
0.00846 |
| 2.4 |
252.0 |
0.00591 |
0.00138 |
3.21e-03 |
0.00861 |
| 2.5 |
317.0 |
0.00600 |
0.00140 |
3.25e-03 |
0.00874 |
| 2.6 |
399.0 |
0.00603 |
0.00140 |
3.28e-03 |
0.00877 |
| 2.7 |
502.0 |
0.00634 |
0.00150 |
3.40e-03 |
0.00928 |
| 2.8 |
632.0 |
0.00609 |
0.00148 |
3.20e-03 |
0.00899 |
| 2.9 |
796.0 |
0.00586 |
0.00149 |
2.94e-03 |
0.00879 |
| 3.0 |
1000.0 |
0.00573 |
0.00147 |
2.85e-03 |
0.00862 |
| 3.1 |
1260.0 |
0.00567 |
0.00149 |
2.76e-03 |
0.00858 |
| 3.2 |
1590.0 |
0.00504 |
0.00145 |
2.18e-03 |
0.00789 |
| 3.3 |
2000.0 |
0.00466 |
0.00146 |
1.80e-03 |
0.00752 |
| 3.4 |
2520.0 |
0.00334 |
0.00130 |
8.05e-04 |
0.00588 |
| 3.5 |
3170.0 |
0.00399 |
0.00157 |
9.18e-04 |
0.00707 |
| 3.6 |
3990.0 |
0.00286 |
0.00143 |
4.31e-05 |
0.00567 |
| 3.7 |
5020.0 |
0.00338 |
0.00191 |
-3.73e-04 |
0.00712 |
Unscaled (monotone)

| 1.3 |
20.0 |
0.0000 |
0.00586 |
0.00105 |
0.003810 |
0.00791 |
| 1.4 |
25.2 |
0.0405 |
0.00586 |
0.00136 |
0.003200 |
0.00852 |
| 1.5 |
31.7 |
0.0405 |
0.00586 |
0.00136 |
0.003200 |
0.00852 |
| 1.6 |
39.9 |
0.0405 |
0.00586 |
0.00136 |
0.003200 |
0.00852 |
| 1.7 |
50.2 |
0.0415 |
0.00586 |
0.00136 |
0.003190 |
0.00853 |
| 1.8 |
63.2 |
0.0423 |
0.00586 |
0.00133 |
0.003250 |
0.00847 |
| 1.9 |
79.6 |
0.0423 |
0.00586 |
0.00133 |
0.003250 |
0.00847 |
| 2.0 |
100.0 |
0.0453 |
0.00586 |
0.00132 |
0.003260 |
0.00846 |
| 2.1 |
126.0 |
0.0504 |
0.00586 |
0.00133 |
0.003260 |
0.00846 |
| 2.2 |
159.0 |
0.0537 |
0.00586 |
0.00132 |
0.003270 |
0.00845 |
| 2.3 |
200.0 |
0.0670 |
0.00586 |
0.00135 |
0.003220 |
0.00850 |
| 2.4 |
252.0 |
0.0759 |
0.00586 |
0.00138 |
0.003160 |
0.00856 |
| 2.5 |
317.0 |
0.0956 |
0.00586 |
0.00140 |
0.003120 |
0.00861 |
| 2.6 |
399.0 |
0.1050 |
0.00586 |
0.00140 |
0.003120 |
0.00861 |
| 2.7 |
502.0 |
0.1240 |
0.00586 |
0.00150 |
0.002920 |
0.00880 |
| 2.8 |
632.0 |
0.1280 |
0.00586 |
0.00148 |
0.002970 |
0.00876 |
| 2.9 |
796.0 |
0.1650 |
0.00586 |
0.00149 |
0.002930 |
0.00879 |
| 3.0 |
1000.0 |
0.2120 |
0.00573 |
0.00147 |
0.002850 |
0.00862 |
| 3.1 |
1260.0 |
0.2650 |
0.00567 |
0.00149 |
0.002760 |
0.00858 |
| 3.2 |
1590.0 |
0.3330 |
0.00504 |
0.00145 |
0.002180 |
0.00789 |
| 3.3 |
2000.0 |
0.3890 |
0.00466 |
0.00146 |
0.001800 |
0.00752 |
| 3.4 |
2520.0 |
0.4460 |
0.00367 |
0.00130 |
0.001130 |
0.00621 |
| 3.5 |
3170.0 |
0.5660 |
0.00367 |
0.00157 |
0.000594 |
0.00674 |
| 3.6 |
3990.0 |
0.6330 |
0.00312 |
0.00143 |
0.000303 |
0.00593 |
| 3.7 |
5020.0 |
0.7300 |
0.00312 |
0.00191 |
-0.000633 |
0.00686 |
VE scale (1 minus risk / placebo risk) (monotone)

| 1.3 |
20.0 |
0.350 |
0.138 |
0.07890 |
0.621 |
| 1.4 |
25.2 |
0.350 |
0.179 |
-0.00144 |
0.702 |
| 1.5 |
31.7 |
0.350 |
0.179 |
-0.00144 |
0.702 |
| 1.6 |
39.9 |
0.350 |
0.179 |
-0.00144 |
0.702 |
| 1.7 |
50.2 |
0.350 |
0.180 |
-0.00364 |
0.704 |
| 1.8 |
63.2 |
0.350 |
0.176 |
0.00506 |
0.695 |
| 1.9 |
79.6 |
0.350 |
0.176 |
0.00506 |
0.695 |
| 2.0 |
100.0 |
0.350 |
0.175 |
0.00667 |
0.693 |
| 2.1 |
126.0 |
0.350 |
0.176 |
0.00572 |
0.694 |
| 2.2 |
159.0 |
0.350 |
0.175 |
0.00739 |
0.693 |
| 2.3 |
200.0 |
0.350 |
0.178 |
0.00118 |
0.699 |
| 2.4 |
252.0 |
0.350 |
0.182 |
-0.00703 |
0.707 |
| 2.5 |
317.0 |
0.350 |
0.185 |
-0.01290 |
0.713 |
| 2.6 |
399.0 |
0.350 |
0.185 |
-0.01300 |
0.713 |
| 2.7 |
502.0 |
0.350 |
0.199 |
-0.03930 |
0.739 |
| 2.8 |
632.0 |
0.350 |
0.195 |
-0.03270 |
0.733 |
| 2.9 |
796.0 |
0.350 |
0.197 |
-0.03710 |
0.737 |
| 3.0 |
1000.0 |
0.364 |
0.193 |
-0.01450 |
0.743 |
| 3.1 |
1260.0 |
0.371 |
0.195 |
-0.01030 |
0.752 |
| 3.2 |
1590.0 |
0.441 |
0.185 |
0.07930 |
0.804 |
| 3.3 |
2000.0 |
0.483 |
0.182 |
0.12600 |
0.841 |
| 3.4 |
2520.0 |
0.593 |
0.155 |
0.28900 |
0.897 |
| 3.5 |
3170.0 |
0.593 |
0.188 |
0.22500 |
0.961 |
| 3.6 |
3990.0 |
0.654 |
0.168 |
0.32400 |
0.984 |
| 3.7 |
5020.0 |
0.654 |
0.224 |
0.21500 |
1.090 |
Placebo
Not monotone

| 1.3 |
20.0 |
0.00902 |
0.00139 |
6.29e-03 |
0.01170 |
| 1.4 |
25.2 |
0.00577 |
0.00162 |
2.59e-03 |
0.00896 |
| 1.5 |
31.7 |
0.00577 |
0.00162 |
2.59e-03 |
0.00896 |
| 1.6 |
39.9 |
0.00577 |
0.00162 |
2.59e-03 |
0.00896 |
| 1.7 |
50.2 |
0.00589 |
0.00168 |
2.60e-03 |
0.00917 |
| 1.8 |
63.2 |
0.00554 |
0.00163 |
2.35e-03 |
0.00874 |
| 1.9 |
79.6 |
0.00487 |
0.00154 |
1.86e-03 |
0.00788 |
| 2.0 |
100.0 |
0.00414 |
0.00142 |
1.36e-03 |
0.00692 |
| 2.1 |
126.0 |
0.00325 |
0.00141 |
4.97e-04 |
0.00601 |
| 2.2 |
159.0 |
0.00244 |
0.00122 |
4.41e-05 |
0.00483 |
| 2.3 |
200.0 |
0.00207 |
0.00109 |
-6.31e-05 |
0.00421 |
| 2.4 |
252.0 |
0.00205 |
0.00102 |
4.42e-05 |
0.00405 |
Monotone

| 1.3 |
20.0 |
0.000 |
0.00902 |
0.00139 |
6.29e-03 |
0.01170 |
| 1.4 |
25.2 |
0.259 |
0.00580 |
0.00162 |
2.62e-03 |
0.00899 |
| 1.5 |
31.7 |
0.259 |
0.00580 |
0.00162 |
2.62e-03 |
0.00899 |
| 1.6 |
39.9 |
0.259 |
0.00580 |
0.00162 |
2.62e-03 |
0.00899 |
| 1.7 |
50.2 |
0.267 |
0.00580 |
0.00168 |
2.52e-03 |
0.00908 |
| 1.8 |
63.2 |
0.272 |
0.00554 |
0.00163 |
2.35e-03 |
0.00874 |
| 1.9 |
79.6 |
0.288 |
0.00487 |
0.00154 |
1.86e-03 |
0.00788 |
| 2.0 |
100.0 |
0.295 |
0.00414 |
0.00142 |
1.36e-03 |
0.00692 |
| 2.1 |
126.0 |
0.347 |
0.00325 |
0.00141 |
4.97e-04 |
0.00601 |
| 2.2 |
159.0 |
0.354 |
0.00244 |
0.00122 |
4.40e-05 |
0.00483 |
| 2.3 |
200.0 |
0.415 |
0.00207 |
0.00109 |
-6.32e-05 |
0.00421 |
| 2.4 |
252.0 |
0.468 |
0.00205 |
0.00102 |
4.42e-05 |
0.00405 |
Vaccine (change)
Unscaled (not monotone)

| -1.5400 |
0.0290 |
0.00522 |
0.00105 |
0.003170 |
0.00727 |
| -1.4400 |
0.0365 |
0.00580 |
0.00126 |
0.003320 |
0.00827 |
| -1.3400 |
0.0459 |
0.00580 |
0.00126 |
0.003320 |
0.00827 |
| -1.2400 |
0.0578 |
0.00582 |
0.00127 |
0.003340 |
0.00831 |
| -1.1400 |
0.0728 |
0.00586 |
0.00128 |
0.003350 |
0.00836 |
| -1.0400 |
0.0917 |
0.00586 |
0.00128 |
0.003350 |
0.00836 |
| -0.9380 |
0.1150 |
0.00564 |
0.00126 |
0.003170 |
0.00811 |
| -0.8380 |
0.1450 |
0.00564 |
0.00126 |
0.003170 |
0.00811 |
| -0.7380 |
0.1830 |
0.00566 |
0.00126 |
0.003180 |
0.00814 |
| -0.6380 |
0.2300 |
0.00568 |
0.00126 |
0.003200 |
0.00816 |
| -0.5380 |
0.2900 |
0.00569 |
0.00126 |
0.003210 |
0.00817 |
| -0.4380 |
0.3650 |
0.00571 |
0.00127 |
0.003220 |
0.00819 |
| -0.3380 |
0.4590 |
0.00571 |
0.00127 |
0.003220 |
0.00820 |
| -0.2380 |
0.5780 |
0.00571 |
0.00127 |
0.003220 |
0.00820 |
| -0.1380 |
0.7280 |
0.00573 |
0.00127 |
0.003230 |
0.00822 |
| -0.0378 |
0.9170 |
0.00549 |
0.00125 |
0.003050 |
0.00794 |
| 0.0622 |
1.1500 |
0.00598 |
0.00139 |
0.003260 |
0.00871 |
| 0.1620 |
1.4500 |
0.00603 |
0.00140 |
0.003280 |
0.00878 |
| 0.2620 |
1.8300 |
0.00627 |
0.00147 |
0.003400 |
0.00915 |
| 0.3620 |
2.3000 |
0.00636 |
0.00149 |
0.003440 |
0.00927 |
| 0.4620 |
2.9000 |
0.00626 |
0.00152 |
0.003280 |
0.00924 |
| 0.5620 |
3.6500 |
0.00604 |
0.00150 |
0.003110 |
0.00897 |
| 0.6620 |
4.5900 |
0.00610 |
0.00149 |
0.003170 |
0.00903 |
| 0.7620 |
5.7800 |
0.00588 |
0.00148 |
0.002980 |
0.00878 |
| 0.8620 |
7.2800 |
0.00604 |
0.00152 |
0.003060 |
0.00903 |
| 0.9620 |
9.1700 |
0.00614 |
0.00155 |
0.003110 |
0.00917 |
| 1.0600 |
11.5000 |
0.00637 |
0.00167 |
0.003100 |
0.00964 |
| 1.1600 |
14.5000 |
0.00659 |
0.00172 |
0.003220 |
0.00995 |
| 1.2600 |
18.3000 |
0.00643 |
0.00178 |
0.002940 |
0.00991 |
| 1.3600 |
23.0000 |
0.00667 |
0.00191 |
0.002930 |
0.01040 |
| 1.4600 |
29.0000 |
0.00552 |
0.00176 |
0.002080 |
0.00897 |
| 1.5600 |
36.5000 |
0.00616 |
0.00201 |
0.002210 |
0.01010 |
| 1.6600 |
45.9000 |
0.00621 |
0.00216 |
0.001980 |
0.01040 |
| 1.7600 |
57.8000 |
0.00745 |
0.00262 |
0.002310 |
0.01260 |
| 1.8600 |
72.8000 |
0.00712 |
0.00253 |
0.002170 |
0.01210 |
| 1.9600 |
91.7000 |
0.00684 |
0.00261 |
0.001720 |
0.01200 |
| 2.0600 |
115.0000 |
0.00490 |
0.00231 |
0.000368 |
0.00943 |
| 2.1600 |
145.0000 |
0.00548 |
0.00254 |
0.000500 |
0.01050 |
| 2.2600 |
183.0000 |
0.00662 |
0.00390 |
-0.001030 |
0.01430 |
Unscaled (monotone)

| -1.5400 |
0.0290 |
0.00000 |
0.00596 |
0.00105 |
0.003910 |
0.00801 |
| -1.4400 |
0.0365 |
0.00300 |
0.00596 |
0.00126 |
0.003490 |
0.00843 |
| -1.3400 |
0.0459 |
0.00300 |
0.00596 |
0.00126 |
0.003490 |
0.00843 |
| -1.2400 |
0.0578 |
0.00601 |
0.00596 |
0.00127 |
0.003470 |
0.00844 |
| -1.1400 |
0.0728 |
0.00901 |
0.00596 |
0.00128 |
0.003450 |
0.00847 |
| -1.0400 |
0.0917 |
0.00901 |
0.00596 |
0.00128 |
0.003450 |
0.00847 |
| -0.9380 |
0.1150 |
0.01030 |
0.00596 |
0.00126 |
0.003490 |
0.00842 |
| -0.8380 |
0.1450 |
0.01030 |
0.00596 |
0.00126 |
0.003490 |
0.00842 |
| -0.7380 |
0.1830 |
0.01330 |
0.00596 |
0.00126 |
0.003480 |
0.00844 |
| -0.6380 |
0.2300 |
0.02130 |
0.00596 |
0.00126 |
0.003480 |
0.00844 |
| -0.5380 |
0.2900 |
0.02730 |
0.00596 |
0.00126 |
0.003480 |
0.00844 |
| -0.4380 |
0.3650 |
0.03330 |
0.00596 |
0.00127 |
0.003470 |
0.00844 |
| -0.3380 |
0.4590 |
0.03410 |
0.00596 |
0.00127 |
0.003470 |
0.00845 |
| -0.2380 |
0.5780 |
0.03410 |
0.00596 |
0.00127 |
0.003470 |
0.00845 |
| -0.1380 |
0.7280 |
0.03790 |
0.00596 |
0.00127 |
0.003460 |
0.00845 |
| -0.0378 |
0.9170 |
0.04260 |
0.00596 |
0.00125 |
0.003520 |
0.00840 |
| 0.0622 |
1.1500 |
0.09540 |
0.00596 |
0.00139 |
0.003230 |
0.00869 |
| 0.1620 |
1.4500 |
0.10200 |
0.00596 |
0.00140 |
0.003210 |
0.00871 |
| 0.2620 |
1.8300 |
0.14700 |
0.00596 |
0.00147 |
0.003080 |
0.00884 |
| 0.3620 |
2.3000 |
0.16500 |
0.00596 |
0.00149 |
0.003040 |
0.00887 |
| 0.4620 |
2.9000 |
0.18400 |
0.00596 |
0.00152 |
0.002980 |
0.00893 |
| 0.5620 |
3.6500 |
0.19700 |
0.00596 |
0.00150 |
0.003030 |
0.00889 |
| 0.6620 |
4.5900 |
0.21900 |
0.00596 |
0.00149 |
0.003030 |
0.00889 |
| 0.7620 |
5.7800 |
0.22800 |
0.00596 |
0.00148 |
0.003060 |
0.00886 |
| 0.8620 |
7.2800 |
0.25900 |
0.00596 |
0.00152 |
0.002980 |
0.00894 |
| 0.9620 |
9.1700 |
0.27800 |
0.00596 |
0.00155 |
0.002930 |
0.00899 |
| 1.0600 |
11.5000 |
0.32800 |
0.00596 |
0.00167 |
0.002690 |
0.00922 |
| 1.1600 |
14.5000 |
0.35700 |
0.00596 |
0.00172 |
0.002590 |
0.00932 |
| 1.2600 |
18.3000 |
0.41800 |
0.00596 |
0.00178 |
0.002470 |
0.00944 |
| 1.3600 |
23.0000 |
0.45300 |
0.00596 |
0.00191 |
0.002210 |
0.00970 |
| 1.4600 |
29.0000 |
0.46000 |
0.00596 |
0.00176 |
0.002510 |
0.00941 |
| 1.5600 |
36.5000 |
0.49300 |
0.00596 |
0.00201 |
0.002010 |
0.00991 |
| 1.6600 |
45.9000 |
0.52500 |
0.00596 |
0.00216 |
0.001730 |
0.01020 |
| 1.7600 |
57.8000 |
0.59400 |
0.00596 |
0.00262 |
0.000814 |
0.01110 |
| 1.8600 |
72.8000 |
0.64800 |
0.00596 |
0.00253 |
0.001010 |
0.01090 |
| 1.9600 |
91.7000 |
0.68100 |
0.00596 |
0.00261 |
0.000844 |
0.01110 |
| 2.0600 |
115.0000 |
0.74000 |
0.00567 |
0.00231 |
0.001140 |
0.01020 |
| 2.1600 |
145.0000 |
0.77600 |
0.00567 |
0.00254 |
0.000682 |
0.01060 |
| 2.2600 |
183.0000 |
0.85300 |
0.00567 |
0.00390 |
-0.001980 |
0.01330 |
VE scale (1 minus risk / placebo risk) (monotone)

| -1.5400 |
0.0290 |
0.339 |
0.139 |
0.06680 |
0.612 |
| -1.4400 |
0.0365 |
0.339 |
0.168 |
0.01080 |
0.668 |
| -1.3400 |
0.0459 |
0.339 |
0.168 |
0.01080 |
0.668 |
| -1.2400 |
0.0578 |
0.339 |
0.169 |
0.00873 |
0.670 |
| -1.1400 |
0.0728 |
0.339 |
0.170 |
0.00594 |
0.673 |
| -1.0400 |
0.0917 |
0.339 |
0.170 |
0.00594 |
0.673 |
| -0.9380 |
0.1150 |
0.339 |
0.167 |
0.01160 |
0.667 |
| -0.8380 |
0.1450 |
0.339 |
0.167 |
0.01160 |
0.667 |
| -0.7380 |
0.1830 |
0.339 |
0.168 |
0.01000 |
0.668 |
| -0.6380 |
0.2300 |
0.339 |
0.168 |
0.00986 |
0.669 |
| -0.5380 |
0.2900 |
0.339 |
0.168 |
0.00981 |
0.669 |
| -0.4380 |
0.3650 |
0.339 |
0.169 |
0.00899 |
0.670 |
| -0.3380 |
0.4590 |
0.339 |
0.169 |
0.00869 |
0.670 |
| -0.2380 |
0.5780 |
0.339 |
0.169 |
0.00869 |
0.670 |
| -0.1380 |
0.7280 |
0.339 |
0.169 |
0.00754 |
0.671 |
| -0.0378 |
0.9170 |
0.339 |
0.166 |
0.01470 |
0.664 |
| 0.0622 |
1.1500 |
0.339 |
0.185 |
-0.02330 |
0.702 |
| 0.1620 |
1.4500 |
0.339 |
0.187 |
-0.02660 |
0.705 |
| 0.2620 |
1.8300 |
0.339 |
0.195 |
-0.04330 |
0.722 |
| 0.3620 |
2.3000 |
0.339 |
0.198 |
-0.04830 |
0.727 |
| 0.4620 |
2.9000 |
0.339 |
0.202 |
-0.05630 |
0.735 |
| 0.5620 |
3.6500 |
0.339 |
0.199 |
-0.05050 |
0.729 |
| 0.6620 |
4.5900 |
0.339 |
0.199 |
-0.04990 |
0.728 |
| 0.7620 |
5.7800 |
0.339 |
0.197 |
-0.04640 |
0.725 |
| 0.8620 |
7.2800 |
0.339 |
0.202 |
-0.05730 |
0.736 |
| 0.9620 |
9.1700 |
0.339 |
0.206 |
-0.06380 |
0.742 |
| 1.0600 |
11.5000 |
0.339 |
0.221 |
-0.09480 |
0.773 |
| 1.1600 |
14.5000 |
0.339 |
0.228 |
-0.10800 |
0.787 |
| 1.2600 |
18.3000 |
0.339 |
0.236 |
-0.12400 |
0.802 |
| 1.3600 |
23.0000 |
0.339 |
0.254 |
-0.15900 |
0.837 |
| 1.4600 |
29.0000 |
0.339 |
0.234 |
-0.11900 |
0.797 |
| 1.5600 |
36.5000 |
0.339 |
0.268 |
-0.18600 |
0.864 |
| 1.6600 |
45.9000 |
0.339 |
0.286 |
-0.22200 |
0.901 |
| 1.7600 |
57.8000 |
0.339 |
0.349 |
-0.34500 |
1.020 |
| 1.8600 |
72.8000 |
0.339 |
0.336 |
-0.31900 |
0.997 |
| 1.9600 |
91.7000 |
0.339 |
0.347 |
-0.34100 |
1.020 |
| 2.0600 |
115.0000 |
0.372 |
0.303 |
-0.22200 |
0.965 |
| 2.1600 |
145.0000 |
0.372 |
0.333 |
-0.28100 |
1.020 |
| 2.2600 |
183.0000 |
0.372 |
0.511 |
-0.62900 |
1.370 |
nAb ID50 BA.4/5
Vaccine
Unscaled (not monotone)

| 1.3 |
20.0 |
0.00522 |
0.00105 |
0.003170 |
0.00727 |
| 1.4 |
25.2 |
0.00579 |
0.00135 |
0.003140 |
0.00844 |
| 1.5 |
31.7 |
0.00579 |
0.00135 |
0.003140 |
0.00844 |
| 1.6 |
39.9 |
0.00579 |
0.00135 |
0.003140 |
0.00844 |
| 1.7 |
50.2 |
0.00582 |
0.00136 |
0.003150 |
0.00850 |
| 1.8 |
63.2 |
0.00582 |
0.00136 |
0.003150 |
0.00850 |
| 1.9 |
79.6 |
0.00583 |
0.00136 |
0.003170 |
0.00849 |
| 2.0 |
100.0 |
0.00531 |
0.00129 |
0.002790 |
0.00784 |
| 2.1 |
126.0 |
0.00531 |
0.00129 |
0.002790 |
0.00784 |
| 2.2 |
159.0 |
0.00542 |
0.00132 |
0.002830 |
0.00800 |
| 2.3 |
200.0 |
0.00577 |
0.00146 |
0.002910 |
0.00863 |
| 2.4 |
252.0 |
0.00582 |
0.00147 |
0.002930 |
0.00870 |
| 2.5 |
317.0 |
0.00588 |
0.00147 |
0.003000 |
0.00876 |
| 2.6 |
399.0 |
0.00542 |
0.00142 |
0.002650 |
0.00820 |
| 2.7 |
502.0 |
0.00515 |
0.00135 |
0.002500 |
0.00781 |
| 2.8 |
632.0 |
0.00525 |
0.00137 |
0.002560 |
0.00795 |
| 2.9 |
796.0 |
0.00491 |
0.00137 |
0.002220 |
0.00759 |
| 3.0 |
1000.0 |
0.00486 |
0.00141 |
0.002090 |
0.00763 |
| 3.1 |
1260.0 |
0.00480 |
0.00146 |
0.001940 |
0.00766 |
| 3.2 |
1590.0 |
0.00440 |
0.00142 |
0.001620 |
0.00719 |
| 3.3 |
2000.0 |
0.00382 |
0.00136 |
0.001160 |
0.00648 |
| 3.4 |
2520.0 |
0.00359 |
0.00150 |
0.000653 |
0.00652 |
| 3.5 |
3170.0 |
0.00380 |
0.00172 |
0.000436 |
0.00716 |
| 3.6 |
3990.0 |
0.00406 |
0.00219 |
-0.000235 |
0.00836 |
Unscaled (monotone)

| 1.3 |
20.0 |
0.0000 |
0.00572 |
0.00105 |
0.003670 |
0.00777 |
| 1.4 |
25.2 |
0.0579 |
0.00572 |
0.00135 |
0.003070 |
0.00837 |
| 1.5 |
31.7 |
0.0579 |
0.00572 |
0.00135 |
0.003070 |
0.00837 |
| 1.6 |
39.9 |
0.0579 |
0.00572 |
0.00135 |
0.003070 |
0.00837 |
| 1.7 |
50.2 |
0.0609 |
0.00572 |
0.00136 |
0.003050 |
0.00840 |
| 1.8 |
63.2 |
0.0612 |
0.00572 |
0.00136 |
0.003050 |
0.00840 |
| 1.9 |
79.6 |
0.0672 |
0.00572 |
0.00136 |
0.003060 |
0.00838 |
| 2.0 |
100.0 |
0.0712 |
0.00558 |
0.00129 |
0.003060 |
0.00810 |
| 2.1 |
126.0 |
0.0712 |
0.00558 |
0.00129 |
0.003060 |
0.00810 |
| 2.2 |
159.0 |
0.0866 |
0.00558 |
0.00132 |
0.002990 |
0.00817 |
| 2.3 |
200.0 |
0.1070 |
0.00558 |
0.00146 |
0.002720 |
0.00844 |
| 2.4 |
252.0 |
0.1150 |
0.00558 |
0.00147 |
0.002690 |
0.00847 |
| 2.5 |
317.0 |
0.1370 |
0.00558 |
0.00147 |
0.002700 |
0.00846 |
| 2.6 |
399.0 |
0.1550 |
0.00542 |
0.00142 |
0.002650 |
0.00820 |
| 2.7 |
502.0 |
0.1860 |
0.00520 |
0.00135 |
0.002550 |
0.00786 |
| 2.8 |
632.0 |
0.2150 |
0.00520 |
0.00137 |
0.002510 |
0.00790 |
| 2.9 |
796.0 |
0.2490 |
0.00491 |
0.00137 |
0.002220 |
0.00759 |
| 3.0 |
1000.0 |
0.2970 |
0.00486 |
0.00141 |
0.002090 |
0.00763 |
| 3.1 |
1260.0 |
0.3600 |
0.00480 |
0.00146 |
0.001940 |
0.00766 |
| 3.2 |
1590.0 |
0.4260 |
0.00440 |
0.00142 |
0.001620 |
0.00719 |
| 3.3 |
2000.0 |
0.4670 |
0.00382 |
0.00136 |
0.001160 |
0.00648 |
| 3.4 |
2520.0 |
0.5750 |
0.00382 |
0.00150 |
0.000883 |
0.00675 |
| 3.5 |
3170.0 |
0.6670 |
0.00382 |
0.00172 |
0.000454 |
0.00718 |
| 3.6 |
3990.0 |
0.7640 |
0.00382 |
0.00219 |
-0.000483 |
0.00812 |
VE scale (1 minus risk / placebo risk) (monotone)

| 1.3 |
20.0 |
0.365 |
0.137 |
0.09620 |
0.635 |
| 1.4 |
25.2 |
0.365 |
0.178 |
0.01750 |
0.713 |
| 1.5 |
31.7 |
0.365 |
0.178 |
0.01750 |
0.713 |
| 1.6 |
39.9 |
0.365 |
0.178 |
0.01750 |
0.713 |
| 1.7 |
50.2 |
0.365 |
0.179 |
0.01410 |
0.717 |
| 1.8 |
63.2 |
0.365 |
0.179 |
0.01410 |
0.717 |
| 1.9 |
79.6 |
0.365 |
0.178 |
0.01620 |
0.715 |
| 2.0 |
100.0 |
0.381 |
0.168 |
0.05200 |
0.710 |
| 2.1 |
126.0 |
0.381 |
0.168 |
0.05200 |
0.710 |
| 2.2 |
159.0 |
0.381 |
0.172 |
0.04400 |
0.718 |
| 2.3 |
200.0 |
0.381 |
0.190 |
0.00806 |
0.754 |
| 2.4 |
252.0 |
0.381 |
0.192 |
0.00491 |
0.757 |
| 2.5 |
317.0 |
0.381 |
0.192 |
0.00556 |
0.757 |
| 2.6 |
399.0 |
0.398 |
0.184 |
0.03880 |
0.758 |
| 2.7 |
502.0 |
0.423 |
0.173 |
0.08310 |
0.763 |
| 2.8 |
632.0 |
0.423 |
0.176 |
0.07810 |
0.768 |
| 2.9 |
796.0 |
0.456 |
0.173 |
0.11700 |
0.795 |
| 3.0 |
1000.0 |
0.461 |
0.178 |
0.11200 |
0.810 |
| 3.1 |
1260.0 |
0.467 |
0.183 |
0.10800 |
0.827 |
| 3.2 |
1590.0 |
0.512 |
0.175 |
0.16800 |
0.855 |
| 3.3 |
2000.0 |
0.577 |
0.164 |
0.25600 |
0.897 |
| 3.4 |
2520.0 |
0.577 |
0.180 |
0.22300 |
0.930 |
| 3.5 |
3170.0 |
0.577 |
0.207 |
0.17200 |
0.982 |
| 3.6 |
3990.0 |
0.577 |
0.264 |
0.05890 |
1.090 |
Placebo
Not monotone

| 1.3 |
20.0 |
0.00902 |
0.001390 |
0.006290 |
0.01170 |
| 1.4 |
25.2 |
0.00425 |
0.001370 |
0.001550 |
0.00694 |
| 1.5 |
31.7 |
0.00425 |
0.001370 |
0.001550 |
0.00694 |
| 1.6 |
39.9 |
0.00425 |
0.001370 |
0.001550 |
0.00694 |
| 1.7 |
50.2 |
0.00453 |
0.001490 |
0.001620 |
0.00744 |
| 1.8 |
63.2 |
0.00451 |
0.001420 |
0.001720 |
0.00729 |
| 1.9 |
79.6 |
0.00475 |
0.001520 |
0.001780 |
0.00773 |
| 2.0 |
100.0 |
0.00361 |
0.001350 |
0.000958 |
0.00625 |
| 2.1 |
126.0 |
0.00233 |
0.001070 |
0.000225 |
0.00443 |
| 2.2 |
159.0 |
0.00195 |
0.000963 |
0.000058 |
0.00383 |
| 2.3 |
200.0 |
0.00152 |
0.000867 |
-0.000183 |
0.00322 |
Monotone

| 1.3 |
20.0 |
0.000 |
0.00902 |
0.001390 |
6.29e-03 |
0.01170 |
| 1.4 |
25.2 |
0.278 |
0.00442 |
0.001370 |
1.72e-03 |
0.00711 |
| 1.5 |
31.7 |
0.278 |
0.00442 |
0.001370 |
1.72e-03 |
0.00711 |
| 1.6 |
39.9 |
0.278 |
0.00442 |
0.001370 |
1.72e-03 |
0.00711 |
| 1.7 |
50.2 |
0.307 |
0.00442 |
0.001490 |
1.50e-03 |
0.00733 |
| 1.8 |
63.2 |
0.335 |
0.00442 |
0.001420 |
1.63e-03 |
0.00720 |
| 1.9 |
79.6 |
0.360 |
0.00442 |
0.001520 |
1.44e-03 |
0.00739 |
| 2.0 |
100.0 |
0.385 |
0.00361 |
0.001350 |
9.58e-04 |
0.00625 |
| 2.1 |
126.0 |
0.404 |
0.00233 |
0.001070 |
2.25e-04 |
0.00443 |
| 2.2 |
159.0 |
0.444 |
0.00195 |
0.000963 |
5.79e-05 |
0.00383 |
| 2.3 |
200.0 |
0.462 |
0.00152 |
0.000867 |
-1.84e-04 |
0.00322 |
Vaccine (change)
Unscaled (not monotone)

| -1.3500 |
0.0443 |
0.00522 |
0.00105 |
0.003170 |
0.00727 |
| -1.2500 |
0.0558 |
0.00580 |
0.00126 |
0.003320 |
0.00827 |
| -1.1500 |
0.0703 |
0.00583 |
0.00127 |
0.003340 |
0.00832 |
| -1.0500 |
0.0885 |
0.00586 |
0.00128 |
0.003360 |
0.00836 |
| -0.9530 |
0.1110 |
0.00588 |
0.00128 |
0.003360 |
0.00839 |
| -0.8530 |
0.1400 |
0.00588 |
0.00128 |
0.003360 |
0.00839 |
| -0.7530 |
0.1770 |
0.00590 |
0.00129 |
0.003370 |
0.00842 |
| -0.6530 |
0.2220 |
0.00592 |
0.00129 |
0.003380 |
0.00846 |
| -0.5530 |
0.2800 |
0.00593 |
0.00129 |
0.003400 |
0.00846 |
| -0.4530 |
0.3520 |
0.00600 |
0.00131 |
0.003430 |
0.00857 |
| -0.3530 |
0.4430 |
0.00600 |
0.00131 |
0.003430 |
0.00857 |
| -0.2530 |
0.5580 |
0.00577 |
0.00128 |
0.003250 |
0.00829 |
| -0.1530 |
0.7030 |
0.00580 |
0.00129 |
0.003270 |
0.00833 |
| -0.0531 |
0.8850 |
0.00580 |
0.00129 |
0.003270 |
0.00833 |
| 0.0469 |
1.1100 |
0.00600 |
0.00139 |
0.003280 |
0.00872 |
| 0.1470 |
1.4000 |
0.00605 |
0.00140 |
0.003310 |
0.00879 |
| 0.2470 |
1.7700 |
0.00612 |
0.00141 |
0.003350 |
0.00889 |
| 0.3470 |
2.2200 |
0.00602 |
0.00143 |
0.003210 |
0.00883 |
| 0.4470 |
2.8000 |
0.00595 |
0.00147 |
0.003060 |
0.00884 |
| 0.5470 |
3.5200 |
0.00609 |
0.00152 |
0.003120 |
0.00907 |
| 0.6470 |
4.4300 |
0.00587 |
0.00149 |
0.002950 |
0.00879 |
| 0.7470 |
5.5800 |
0.00531 |
0.00141 |
0.002560 |
0.00807 |
| 0.8470 |
7.0300 |
0.00472 |
0.00131 |
0.002150 |
0.00730 |
| 0.9470 |
8.8500 |
0.00485 |
0.00135 |
0.002200 |
0.00750 |
| 1.0500 |
11.1000 |
0.00516 |
0.00155 |
0.002120 |
0.00821 |
| 1.1500 |
14.0000 |
0.00575 |
0.00172 |
0.002370 |
0.00913 |
| 1.2500 |
17.7000 |
0.00544 |
0.00168 |
0.002150 |
0.00872 |
| 1.3500 |
22.2000 |
0.00534 |
0.00176 |
0.001890 |
0.00878 |
| 1.4500 |
28.0000 |
0.00526 |
0.00174 |
0.001860 |
0.00866 |
| 1.5500 |
35.2000 |
0.00575 |
0.00192 |
0.001990 |
0.00950 |
| 1.6500 |
44.3000 |
0.00604 |
0.00215 |
0.001830 |
0.01020 |
| 1.7500 |
55.8000 |
0.00728 |
0.00255 |
0.002280 |
0.01230 |
| 1.8500 |
70.3000 |
0.00779 |
0.00291 |
0.002080 |
0.01350 |
| 1.9500 |
88.5000 |
0.00593 |
0.00253 |
0.000958 |
0.01090 |
| 2.0500 |
111.0000 |
0.00676 |
0.00295 |
0.000979 |
0.01250 |
| 2.1500 |
140.0000 |
0.00707 |
0.00340 |
0.000417 |
0.01370 |
Unscaled (monotone)

| -1.3500 |
0.0443 |
0.00000 |
0.00589 |
0.00105 |
0.003840 |
0.00794 |
| -1.2500 |
0.0558 |
0.00300 |
0.00589 |
0.00126 |
0.003420 |
0.00836 |
| -1.1500 |
0.0703 |
0.00601 |
0.00589 |
0.00127 |
0.003400 |
0.00838 |
| -1.0500 |
0.0885 |
0.01200 |
0.00589 |
0.00128 |
0.003390 |
0.00839 |
| -0.9530 |
0.1110 |
0.01310 |
0.00589 |
0.00128 |
0.003370 |
0.00840 |
| -0.8530 |
0.1400 |
0.01310 |
0.00589 |
0.00128 |
0.003370 |
0.00840 |
| -0.7530 |
0.1770 |
0.01610 |
0.00589 |
0.00129 |
0.003360 |
0.00841 |
| -0.6530 |
0.2220 |
0.01720 |
0.00589 |
0.00129 |
0.003350 |
0.00843 |
| -0.5530 |
0.2800 |
0.02410 |
0.00589 |
0.00129 |
0.003350 |
0.00842 |
| -0.4530 |
0.3520 |
0.03190 |
0.00589 |
0.00131 |
0.003320 |
0.00846 |
| -0.3530 |
0.4430 |
0.03190 |
0.00589 |
0.00131 |
0.003320 |
0.00846 |
| -0.2530 |
0.5580 |
0.03870 |
0.00589 |
0.00128 |
0.003370 |
0.00841 |
| -0.1530 |
0.7030 |
0.04860 |
0.00589 |
0.00129 |
0.003360 |
0.00842 |
| -0.0531 |
0.8850 |
0.04860 |
0.00589 |
0.00129 |
0.003360 |
0.00842 |
| 0.0469 |
1.1100 |
0.10700 |
0.00589 |
0.00139 |
0.003160 |
0.00861 |
| 0.1470 |
1.4000 |
0.11800 |
0.00589 |
0.00140 |
0.003150 |
0.00863 |
| 0.2470 |
1.7700 |
0.13500 |
0.00589 |
0.00141 |
0.003120 |
0.00865 |
| 0.3470 |
2.2200 |
0.16400 |
0.00589 |
0.00143 |
0.003080 |
0.00869 |
| 0.4470 |
2.8000 |
0.18900 |
0.00589 |
0.00147 |
0.003000 |
0.00878 |
| 0.5470 |
3.5200 |
0.20900 |
0.00589 |
0.00152 |
0.002910 |
0.00887 |
| 0.6470 |
4.4300 |
0.23700 |
0.00587 |
0.00149 |
0.002950 |
0.00879 |
| 0.7470 |
5.5800 |
0.26000 |
0.00548 |
0.00141 |
0.002720 |
0.00824 |
| 0.8470 |
7.0300 |
0.27700 |
0.00548 |
0.00131 |
0.002910 |
0.00805 |
| 0.9470 |
8.8500 |
0.29200 |
0.00548 |
0.00135 |
0.002830 |
0.00813 |
| 1.0500 |
11.1000 |
0.34900 |
0.00548 |
0.00155 |
0.002430 |
0.00853 |
| 1.1500 |
14.0000 |
0.38000 |
0.00548 |
0.00172 |
0.002100 |
0.00886 |
| 1.2500 |
17.7000 |
0.39400 |
0.00548 |
0.00168 |
0.002190 |
0.00877 |
| 1.3500 |
22.2000 |
0.43600 |
0.00548 |
0.00176 |
0.002040 |
0.00892 |
| 1.4500 |
28.0000 |
0.50400 |
0.00548 |
0.00174 |
0.002080 |
0.00888 |
| 1.5500 |
35.2000 |
0.55400 |
0.00548 |
0.00192 |
0.001730 |
0.00923 |
| 1.6500 |
44.3000 |
0.60100 |
0.00548 |
0.00215 |
0.001270 |
0.00969 |
| 1.7500 |
55.8000 |
0.63500 |
0.00548 |
0.00255 |
0.000483 |
0.01050 |
| 1.8500 |
70.3000 |
0.68000 |
0.00548 |
0.00291 |
-0.000233 |
0.01120 |
| 1.9500 |
88.5000 |
0.73800 |
0.00548 |
0.00253 |
0.000512 |
0.01040 |
| 2.0500 |
111.0000 |
0.78100 |
0.00548 |
0.00295 |
-0.000301 |
0.01130 |
| 2.1500 |
140.0000 |
0.83100 |
0.00548 |
0.00340 |
-0.001180 |
0.01210 |
VE scale (1 minus risk / placebo risk) (monotone)

| -1.3500 |
0.0443 |
0.347 |
0.139 |
0.0757 |
0.619 |
| -1.2500 |
0.0558 |
0.347 |
0.167 |
0.0198 |
0.674 |
| -1.1500 |
0.0703 |
0.347 |
0.168 |
0.0172 |
0.677 |
| -1.0500 |
0.0885 |
0.347 |
0.169 |
0.0158 |
0.678 |
| -0.9530 |
0.1110 |
0.347 |
0.170 |
0.0144 |
0.680 |
| -0.8530 |
0.1400 |
0.347 |
0.170 |
0.0144 |
0.680 |
| -0.7530 |
0.1770 |
0.347 |
0.171 |
0.0127 |
0.682 |
| -0.6530 |
0.2220 |
0.347 |
0.171 |
0.0110 |
0.683 |
| -0.5530 |
0.2800 |
0.347 |
0.171 |
0.0117 |
0.683 |
| -0.4530 |
0.3520 |
0.347 |
0.174 |
0.0066 |
0.688 |
| -0.3530 |
0.4430 |
0.347 |
0.174 |
0.0066 |
0.688 |
| -0.2530 |
0.5580 |
0.347 |
0.170 |
0.0136 |
0.681 |
| -0.1530 |
0.7030 |
0.347 |
0.171 |
0.0120 |
0.682 |
| -0.0531 |
0.8850 |
0.347 |
0.171 |
0.0120 |
0.682 |
| 0.0469 |
1.1100 |
0.347 |
0.184 |
-0.0135 |
0.708 |
| 0.1470 |
1.4000 |
0.347 |
0.185 |
-0.0156 |
0.710 |
| 0.2470 |
1.7700 |
0.347 |
0.187 |
-0.0192 |
0.713 |
| 0.3470 |
2.2200 |
0.347 |
0.190 |
-0.0246 |
0.719 |
| 0.4470 |
2.8000 |
0.347 |
0.195 |
-0.0356 |
0.730 |
| 0.5470 |
3.5200 |
0.347 |
0.201 |
-0.0473 |
0.742 |
| 0.6470 |
4.4300 |
0.349 |
0.197 |
-0.0368 |
0.736 |
| 0.7470 |
5.5800 |
0.392 |
0.182 |
0.0346 |
0.750 |
| 0.8470 |
7.0300 |
0.392 |
0.170 |
0.0584 |
0.726 |
| 0.9470 |
8.8500 |
0.392 |
0.176 |
0.0482 |
0.736 |
| 1.0500 |
11.1000 |
0.392 |
0.202 |
-0.0030 |
0.788 |
| 1.1500 |
14.0000 |
0.392 |
0.224 |
-0.0462 |
0.831 |
| 1.2500 |
17.7000 |
0.392 |
0.218 |
-0.0342 |
0.819 |
| 1.3500 |
22.2000 |
0.392 |
0.228 |
-0.0544 |
0.839 |
| 1.4500 |
28.0000 |
0.392 |
0.225 |
-0.0490 |
0.834 |
| 1.5500 |
35.2000 |
0.392 |
0.249 |
-0.0948 |
0.879 |
| 1.6500 |
44.3000 |
0.392 |
0.279 |
-0.1540 |
0.939 |
| 1.7500 |
55.8000 |
0.392 |
0.331 |
-0.2560 |
1.040 |
| 1.8500 |
70.3000 |
0.392 |
0.378 |
-0.3490 |
1.130 |
| 1.9500 |
88.5000 |
0.392 |
0.329 |
-0.2520 |
1.040 |
| 2.0500 |
111.0000 |
0.392 |
0.383 |
-0.3580 |
1.140 |
| 2.1500 |
140.0000 |
0.392 |
0.441 |
-0.4720 |
1.260 |
nAb ID50 Breadth Score
Vaccine
Unscaled (not monotone)

| 1.3 |
20.0 |
0.00522 |
0.00105 |
0.003170 |
0.00727 |
| 1.4 |
25.2 |
0.00596 |
0.00132 |
0.003370 |
0.00854 |
| 1.5 |
31.7 |
0.00596 |
0.00132 |
0.003370 |
0.00855 |
| 1.6 |
39.9 |
0.00597 |
0.00131 |
0.003400 |
0.00853 |
| 1.7 |
50.2 |
0.00606 |
0.00134 |
0.003430 |
0.00870 |
| 1.8 |
63.2 |
0.00617 |
0.00139 |
0.003450 |
0.00890 |
| 1.9 |
79.6 |
0.00593 |
0.00136 |
0.003270 |
0.00860 |
| 2.0 |
100.0 |
0.00595 |
0.00137 |
0.003280 |
0.00863 |
| 2.1 |
126.0 |
0.00571 |
0.00134 |
0.003100 |
0.00833 |
| 2.2 |
159.0 |
0.00571 |
0.00132 |
0.003120 |
0.00831 |
| 2.3 |
200.0 |
0.00572 |
0.00132 |
0.003130 |
0.00831 |
| 2.4 |
252.0 |
0.00580 |
0.00135 |
0.003160 |
0.00844 |
| 2.5 |
317.0 |
0.00587 |
0.00135 |
0.003220 |
0.00852 |
| 2.6 |
399.0 |
0.00590 |
0.00136 |
0.003230 |
0.00858 |
| 2.7 |
502.0 |
0.00601 |
0.00140 |
0.003270 |
0.00875 |
| 2.8 |
632.0 |
0.00609 |
0.00142 |
0.003300 |
0.00888 |
| 2.9 |
796.0 |
0.00590 |
0.00146 |
0.003050 |
0.00876 |
| 3.0 |
1000.0 |
0.00593 |
0.00146 |
0.003070 |
0.00879 |
| 3.1 |
1260.0 |
0.00569 |
0.00143 |
0.002900 |
0.00849 |
| 3.2 |
1590.0 |
0.00559 |
0.00144 |
0.002770 |
0.00842 |
| 3.3 |
2000.0 |
0.00561 |
0.00148 |
0.002720 |
0.00851 |
| 3.4 |
2520.0 |
0.00463 |
0.00140 |
0.001900 |
0.00737 |
| 3.5 |
3170.0 |
0.00421 |
0.00137 |
0.001530 |
0.00689 |
| 3.6 |
3990.0 |
0.00418 |
0.00141 |
0.001410 |
0.00694 |
| 3.7 |
5020.0 |
0.00355 |
0.00146 |
0.000700 |
0.00641 |
| 3.8 |
6320.0 |
0.00266 |
0.00144 |
-0.000171 |
0.00549 |
Unscaled (monotone)

| 1.3 |
20.0 |
0.0000 |
0.00590 |
0.00105 |
0.003850 |
0.00795 |
| 1.4 |
25.2 |
0.0122 |
0.00590 |
0.00132 |
0.003320 |
0.00848 |
| 1.5 |
31.7 |
0.0127 |
0.00590 |
0.00132 |
0.003320 |
0.00849 |
| 1.6 |
39.9 |
0.0157 |
0.00590 |
0.00131 |
0.003340 |
0.00846 |
| 1.7 |
50.2 |
0.0250 |
0.00590 |
0.00134 |
0.003270 |
0.00854 |
| 1.8 |
63.2 |
0.0358 |
0.00590 |
0.00139 |
0.003180 |
0.00863 |
| 1.9 |
79.6 |
0.0366 |
0.00590 |
0.00136 |
0.003240 |
0.00857 |
| 2.0 |
100.0 |
0.0381 |
0.00590 |
0.00137 |
0.003220 |
0.00858 |
| 2.1 |
126.0 |
0.0384 |
0.00586 |
0.00134 |
0.003250 |
0.00848 |
| 2.2 |
159.0 |
0.0444 |
0.00586 |
0.00132 |
0.003270 |
0.00846 |
| 2.3 |
200.0 |
0.0485 |
0.00586 |
0.00132 |
0.003270 |
0.00845 |
| 2.4 |
252.0 |
0.0591 |
0.00586 |
0.00135 |
0.003220 |
0.00851 |
| 2.5 |
317.0 |
0.0796 |
0.00586 |
0.00135 |
0.003210 |
0.00852 |
| 2.6 |
399.0 |
0.0836 |
0.00586 |
0.00136 |
0.003190 |
0.00854 |
| 2.7 |
502.0 |
0.1010 |
0.00586 |
0.00140 |
0.003120 |
0.00860 |
| 2.8 |
632.0 |
0.1150 |
0.00586 |
0.00142 |
0.003080 |
0.00865 |
| 2.9 |
796.0 |
0.1480 |
0.00586 |
0.00146 |
0.003010 |
0.00872 |
| 3.0 |
1000.0 |
0.1530 |
0.00586 |
0.00146 |
0.003000 |
0.00872 |
| 3.1 |
1260.0 |
0.1600 |
0.00569 |
0.00143 |
0.002900 |
0.00849 |
| 3.2 |
1590.0 |
0.1920 |
0.00560 |
0.00144 |
0.002780 |
0.00843 |
| 3.3 |
2000.0 |
0.2470 |
0.00560 |
0.00148 |
0.002710 |
0.00849 |
| 3.4 |
2520.0 |
0.3050 |
0.00463 |
0.00140 |
0.001900 |
0.00737 |
| 3.5 |
3170.0 |
0.3660 |
0.00421 |
0.00137 |
0.001530 |
0.00689 |
| 3.6 |
3990.0 |
0.4640 |
0.00418 |
0.00141 |
0.001410 |
0.00694 |
| 3.7 |
5020.0 |
0.5600 |
0.00355 |
0.00146 |
0.000700 |
0.00641 |
| 3.8 |
6320.0 |
0.6650 |
0.00266 |
0.00144 |
-0.000171 |
0.00549 |
VE scale (1 minus risk / placebo risk) (monotone)

| 1.3 |
20.0 |
0.346 |
0.139 |
0.073800 |
0.617 |
| 1.4 |
25.2 |
0.346 |
0.175 |
0.003240 |
0.688 |
| 1.5 |
31.7 |
0.346 |
0.175 |
0.002810 |
0.688 |
| 1.6 |
39.9 |
0.346 |
0.173 |
0.006070 |
0.685 |
| 1.7 |
50.2 |
0.346 |
0.178 |
-0.003640 |
0.695 |
| 1.8 |
63.2 |
0.346 |
0.184 |
-0.015900 |
0.707 |
| 1.9 |
79.6 |
0.346 |
0.180 |
-0.007740 |
0.699 |
| 2.0 |
100.0 |
0.346 |
0.181 |
-0.009530 |
0.701 |
| 2.1 |
126.0 |
0.350 |
0.177 |
0.003560 |
0.696 |
| 2.2 |
159.0 |
0.350 |
0.175 |
0.006870 |
0.693 |
| 2.3 |
200.0 |
0.350 |
0.175 |
0.007390 |
0.692 |
| 2.4 |
252.0 |
0.350 |
0.178 |
0.000296 |
0.699 |
| 2.5 |
317.0 |
0.350 |
0.179 |
-0.001140 |
0.701 |
| 2.6 |
399.0 |
0.350 |
0.180 |
-0.003910 |
0.703 |
| 2.7 |
502.0 |
0.350 |
0.185 |
-0.012800 |
0.712 |
| 2.8 |
632.0 |
0.350 |
0.188 |
-0.018600 |
0.718 |
| 2.9 |
796.0 |
0.350 |
0.193 |
-0.028200 |
0.728 |
| 3.0 |
1000.0 |
0.350 |
0.193 |
-0.028600 |
0.728 |
| 3.1 |
1260.0 |
0.369 |
0.187 |
0.001840 |
0.735 |
| 3.2 |
1590.0 |
0.379 |
0.188 |
0.009830 |
0.748 |
| 3.3 |
2000.0 |
0.379 |
0.193 |
0.001140 |
0.756 |
| 3.4 |
2520.0 |
0.486 |
0.174 |
0.145000 |
0.827 |
| 3.5 |
3170.0 |
0.533 |
0.167 |
0.205000 |
0.861 |
| 3.6 |
3990.0 |
0.537 |
0.172 |
0.199000 |
0.875 |
| 3.7 |
5020.0 |
0.606 |
0.174 |
0.266000 |
0.946 |
| 3.8 |
6320.0 |
0.705 |
0.167 |
0.378000 |
1.030 |
Placebo
Not monotone

| 1.3 |
20.0 |
0.00902 |
0.001390 |
0.006290 |
0.01170 |
| 1.4 |
25.2 |
0.00858 |
0.001820 |
0.005010 |
0.01210 |
| 1.5 |
31.7 |
0.00848 |
0.001850 |
0.004840 |
0.01210 |
| 1.6 |
39.9 |
0.00683 |
0.001680 |
0.003530 |
0.01010 |
| 1.7 |
50.2 |
0.00521 |
0.001500 |
0.002260 |
0.00815 |
| 1.8 |
63.2 |
0.00470 |
0.001470 |
0.001830 |
0.00758 |
| 1.9 |
79.6 |
0.00445 |
0.001390 |
0.001720 |
0.00718 |
| 2.0 |
100.0 |
0.00405 |
0.001330 |
0.001450 |
0.00666 |
| 2.1 |
126.0 |
0.00425 |
0.001420 |
0.001470 |
0.00703 |
| 2.2 |
159.0 |
0.00395 |
0.001390 |
0.001220 |
0.00668 |
| 2.3 |
200.0 |
0.00355 |
0.001320 |
0.000956 |
0.00614 |
| 2.4 |
252.0 |
0.00307 |
0.001350 |
0.000429 |
0.00571 |
| 2.5 |
317.0 |
0.00262 |
0.001260 |
0.000159 |
0.00508 |
| 2.6 |
399.0 |
0.00156 |
0.000900 |
-0.000208 |
0.00332 |
| 2.7 |
502.0 |
0.00163 |
0.000944 |
-0.000217 |
0.00348 |
Monotone

| 1.3 |
20.0 |
0.000 |
0.00902 |
0.001390 |
0.006290 |
0.01170 |
| 1.4 |
25.2 |
0.105 |
0.00858 |
0.001820 |
0.005010 |
0.01210 |
| 1.5 |
31.7 |
0.157 |
0.00848 |
0.001850 |
0.004840 |
0.01210 |
| 1.6 |
39.9 |
0.184 |
0.00683 |
0.001680 |
0.003530 |
0.01010 |
| 1.7 |
50.2 |
0.254 |
0.00521 |
0.001500 |
0.002260 |
0.00815 |
| 1.8 |
63.2 |
0.269 |
0.00470 |
0.001470 |
0.001830 |
0.00758 |
| 1.9 |
79.6 |
0.311 |
0.00445 |
0.001390 |
0.001720 |
0.00718 |
| 2.0 |
100.0 |
0.327 |
0.00415 |
0.001330 |
0.001550 |
0.00676 |
| 2.1 |
126.0 |
0.371 |
0.00415 |
0.001420 |
0.001370 |
0.00693 |
| 2.2 |
159.0 |
0.383 |
0.00395 |
0.001390 |
0.001220 |
0.00668 |
| 2.3 |
200.0 |
0.386 |
0.00355 |
0.001320 |
0.000956 |
0.00614 |
| 2.4 |
252.0 |
0.424 |
0.00307 |
0.001350 |
0.000429 |
0.00571 |
| 2.5 |
317.0 |
0.439 |
0.00262 |
0.001260 |
0.000159 |
0.00508 |
| 2.6 |
399.0 |
0.476 |
0.00159 |
0.000900 |
-0.000169 |
0.00336 |
| 2.7 |
502.0 |
0.507 |
0.00159 |
0.000944 |
-0.000256 |
0.00344 |
Vaccine (change)
Unscaled (not monotone)

| -1.0200 |
0.0955 |
0.00522 |
0.00105 |
0.00317 |
0.00727 |
| -0.9200 |
0.1200 |
0.00582 |
0.00127 |
0.00334 |
0.00830 |
| -0.8200 |
0.1510 |
0.00586 |
0.00128 |
0.00335 |
0.00837 |
| -0.7200 |
0.1900 |
0.00589 |
0.00128 |
0.00337 |
0.00840 |
| -0.6200 |
0.2400 |
0.00592 |
0.00129 |
0.00338 |
0.00846 |
| -0.5200 |
0.3020 |
0.00593 |
0.00129 |
0.00340 |
0.00846 |
| -0.4200 |
0.3800 |
0.00594 |
0.00129 |
0.00340 |
0.00847 |
| -0.3200 |
0.4780 |
0.00594 |
0.00129 |
0.00340 |
0.00848 |
| -0.2200 |
0.6020 |
0.00595 |
0.00130 |
0.00341 |
0.00849 |
| -0.1200 |
0.7580 |
0.00596 |
0.00130 |
0.00341 |
0.00850 |
| -0.0202 |
0.9550 |
0.00602 |
0.00132 |
0.00345 |
0.00860 |
| 0.0798 |
1.2000 |
0.00608 |
0.00137 |
0.00340 |
0.00876 |
| 0.1800 |
1.5100 |
0.00589 |
0.00135 |
0.00325 |
0.00853 |
| 0.2800 |
1.9000 |
0.00600 |
0.00138 |
0.00330 |
0.00870 |
| 0.3800 |
2.4000 |
0.00630 |
0.00147 |
0.00343 |
0.00918 |
| 0.4800 |
3.0200 |
0.00623 |
0.00151 |
0.00327 |
0.00918 |
| 0.5800 |
3.8000 |
0.00602 |
0.00148 |
0.00311 |
0.00893 |
| 0.6800 |
4.7800 |
0.00580 |
0.00145 |
0.00295 |
0.00865 |
| 0.7800 |
6.0200 |
0.00555 |
0.00142 |
0.00276 |
0.00834 |
| 0.8800 |
7.5800 |
0.00563 |
0.00145 |
0.00280 |
0.00846 |
| 0.9800 |
9.5500 |
0.00603 |
0.00157 |
0.00296 |
0.00910 |
| 1.0800 |
12.0000 |
0.00558 |
0.00153 |
0.00259 |
0.00857 |
| 1.1800 |
15.1000 |
0.00594 |
0.00162 |
0.00276 |
0.00913 |
| 1.2800 |
19.0000 |
0.00526 |
0.00158 |
0.00217 |
0.00836 |
| 1.3800 |
24.0000 |
0.00543 |
0.00165 |
0.00221 |
0.00866 |
| 1.4800 |
30.2000 |
0.00560 |
0.00178 |
0.00211 |
0.00909 |
| 1.5800 |
38.0000 |
0.00585 |
0.00189 |
0.00215 |
0.00956 |
| 1.6800 |
47.8000 |
0.00601 |
0.00205 |
0.00200 |
0.01000 |
| 1.7800 |
60.2000 |
0.00713 |
0.00239 |
0.00245 |
0.01180 |
| 1.8800 |
75.8000 |
0.00745 |
0.00253 |
0.00248 |
0.01240 |
| 1.9800 |
95.5000 |
0.00673 |
0.00254 |
0.00175 |
0.01170 |
| 2.0800 |
120.0000 |
0.00575 |
0.00249 |
0.00087 |
0.01060 |
| 2.1800 |
151.0000 |
0.00342 |
0.00240 |
-0.00127 |
0.00812 |
Unscaled (monotone)

| -1.0200 |
0.0955 |
0.00000 |
0.00593 |
0.00105 |
0.003890 |
0.00798 |
| -0.9200 |
0.1200 |
0.00601 |
0.00593 |
0.00127 |
0.003450 |
0.00842 |
| -0.8200 |
0.1510 |
0.01010 |
0.00593 |
0.00128 |
0.003430 |
0.00844 |
| -0.7200 |
0.1900 |
0.01420 |
0.00593 |
0.00128 |
0.003420 |
0.00845 |
| -0.6200 |
0.2400 |
0.01720 |
0.00593 |
0.00129 |
0.003400 |
0.00847 |
| -0.5200 |
0.3020 |
0.02410 |
0.00593 |
0.00129 |
0.003400 |
0.00847 |
| -0.4200 |
0.3800 |
0.02710 |
0.00593 |
0.00129 |
0.003400 |
0.00847 |
| -0.3200 |
0.4780 |
0.02740 |
0.00593 |
0.00129 |
0.003400 |
0.00847 |
| -0.2200 |
0.6020 |
0.03040 |
0.00593 |
0.00130 |
0.003390 |
0.00848 |
| -0.1200 |
0.7580 |
0.03360 |
0.00593 |
0.00130 |
0.003390 |
0.00848 |
| -0.0202 |
0.9550 |
0.04650 |
0.00593 |
0.00132 |
0.003360 |
0.00851 |
| 0.0798 |
1.2000 |
0.07080 |
0.00593 |
0.00137 |
0.003250 |
0.00862 |
| 0.1800 |
1.5100 |
0.08850 |
0.00593 |
0.00135 |
0.003300 |
0.00857 |
| 0.2800 |
1.9000 |
0.11300 |
0.00593 |
0.00138 |
0.003240 |
0.00863 |
| 0.3800 |
2.4000 |
0.15700 |
0.00593 |
0.00147 |
0.003060 |
0.00881 |
| 0.4800 |
3.0200 |
0.17600 |
0.00593 |
0.00151 |
0.002980 |
0.00889 |
| 0.5800 |
3.8000 |
0.19100 |
0.00593 |
0.00148 |
0.003030 |
0.00884 |
| 0.6800 |
4.7800 |
0.21700 |
0.00590 |
0.00145 |
0.003050 |
0.00875 |
| 0.7800 |
6.0200 |
0.23400 |
0.00590 |
0.00142 |
0.003110 |
0.00868 |
| 0.8800 |
7.5800 |
0.24900 |
0.00590 |
0.00145 |
0.003060 |
0.00873 |
| 0.9800 |
9.5500 |
0.27600 |
0.00590 |
0.00157 |
0.002830 |
0.00897 |
| 1.0800 |
12.0000 |
0.31500 |
0.00590 |
0.00153 |
0.002900 |
0.00889 |
| 1.1800 |
15.1000 |
0.34800 |
0.00590 |
0.00162 |
0.002710 |
0.00908 |
| 1.2800 |
19.0000 |
0.38100 |
0.00590 |
0.00158 |
0.002800 |
0.00899 |
| 1.3800 |
24.0000 |
0.40500 |
0.00590 |
0.00165 |
0.002670 |
0.00912 |
| 1.4800 |
30.2000 |
0.46200 |
0.00590 |
0.00178 |
0.002410 |
0.00938 |
| 1.5800 |
38.0000 |
0.49600 |
0.00590 |
0.00189 |
0.002190 |
0.00960 |
| 1.6800 |
47.8000 |
0.55300 |
0.00590 |
0.00205 |
0.001890 |
0.00991 |
| 1.7800 |
60.2000 |
0.61100 |
0.00590 |
0.00239 |
0.001220 |
0.01060 |
| 1.8800 |
75.8000 |
0.63500 |
0.00590 |
0.00253 |
0.000934 |
0.01090 |
| 1.9800 |
95.5000 |
0.66500 |
0.00590 |
0.00254 |
0.000920 |
0.01090 |
| 2.0800 |
120.0000 |
0.69400 |
0.00575 |
0.00249 |
0.000870 |
0.01060 |
| 2.1800 |
151.0000 |
0.80000 |
0.00342 |
0.00240 |
-0.001270 |
0.00812 |
VE scale (1 minus risk / placebo risk) (monotone)

| -1.0200 |
0.0955 |
0.342 |
0.139 |
0.069700 |
0.614 |
| -0.9200 |
0.1200 |
0.342 |
0.168 |
0.012400 |
0.671 |
| -0.8200 |
0.1510 |
0.342 |
0.170 |
0.008730 |
0.675 |
| -0.7200 |
0.1900 |
0.342 |
0.170 |
0.007810 |
0.676 |
| -0.6200 |
0.2400 |
0.342 |
0.172 |
0.004890 |
0.679 |
| -0.5200 |
0.3020 |
0.342 |
0.172 |
0.005410 |
0.678 |
| -0.4200 |
0.3800 |
0.342 |
0.172 |
0.004990 |
0.679 |
| -0.3200 |
0.4780 |
0.342 |
0.172 |
0.004890 |
0.679 |
| -0.2200 |
0.6020 |
0.342 |
0.172 |
0.004510 |
0.679 |
| -0.1200 |
0.7580 |
0.342 |
0.172 |
0.004000 |
0.680 |
| -0.0202 |
0.9550 |
0.342 |
0.175 |
-0.000417 |
0.684 |
| 0.0798 |
1.2000 |
0.342 |
0.182 |
-0.014100 |
0.698 |
| 0.1800 |
1.5100 |
0.342 |
0.179 |
-0.008640 |
0.692 |
| 0.2800 |
1.9000 |
0.342 |
0.183 |
-0.016200 |
0.700 |
| 0.3800 |
2.4000 |
0.342 |
0.195 |
-0.040000 |
0.724 |
| 0.4800 |
3.0200 |
0.342 |
0.200 |
-0.050200 |
0.734 |
| 0.5800 |
3.8000 |
0.342 |
0.197 |
-0.044400 |
0.728 |
| 0.6800 |
4.7800 |
0.346 |
0.193 |
-0.031600 |
0.724 |
| 0.7800 |
6.0200 |
0.346 |
0.188 |
-0.023300 |
0.715 |
| 0.8800 |
7.5800 |
0.346 |
0.192 |
-0.029300 |
0.721 |
| 0.9800 |
9.5500 |
0.346 |
0.207 |
-0.060600 |
0.753 |
| 1.0800 |
12.0000 |
0.346 |
0.202 |
-0.050700 |
0.743 |
| 1.1800 |
15.1000 |
0.346 |
0.215 |
-0.075600 |
0.768 |
| 1.2800 |
19.0000 |
0.346 |
0.209 |
-0.064500 |
0.757 |
| 1.3800 |
24.0000 |
0.346 |
0.218 |
-0.081300 |
0.773 |
| 1.4800 |
30.2000 |
0.346 |
0.236 |
-0.116000 |
0.808 |
| 1.5800 |
38.0000 |
0.346 |
0.251 |
-0.145000 |
0.837 |
| 1.6800 |
47.8000 |
0.346 |
0.271 |
-0.185000 |
0.877 |
| 1.7800 |
60.2000 |
0.346 |
0.316 |
-0.274000 |
0.966 |
| 1.8800 |
75.8000 |
0.346 |
0.336 |
-0.312000 |
1.000 |
| 1.9800 |
95.5000 |
0.346 |
0.336 |
-0.313000 |
1.010 |
| 2.0800 |
120.0000 |
0.362 |
0.327 |
-0.279000 |
1.000 |
| 2.1800 |
151.0000 |
0.620 |
0.284 |
0.063300 |
1.180 |